OBSCN missense variants in ExAC

OBSCN gene summary
OBSCN variants in

The table below lists the OBSCN missense variants found in the ExAC population database. Click on each variant for more details, including presence in the 1000 Genomes and Exome Sequencing Project databases, a breakdown by ethnic class and the variant's role in inherited cardiac disease. Use the form below to customise the variant selection. The table can be sorted by variant location, variant type or ExAC frequency.




No. Genomic coord.✝ Variant (CDS)▼ Variant (Protein) Variant Type▼ ExAC frequency▼Populations*
1. 228399499 c.15G>C p.Q5H missense 0.00001227●●●●●●
2. 228399500 c.16T>A p.F6I missense 0.00001226●●●●●●
3. 228399519 c.35T>A p.F12Y missense 0.00492109●●●●●●
4. 228399551 c.67G>A p.V23M missense 0.00029544●●●●●●
5. 228399552 c.68T>G p.V23G missense 0.00001228●●●●●●
6. 228399562 c.78C>A p.D26E missense 0.00001204●●●●●●
7. 228399563 c.79G>A p.A27T missense 0.00001203●●●●●●
8. 228399572 c.88A>G p.S30G missense 0.00001170●●●●●●
9. 228399575 c.91T>G p.C31G missense 0.00004670●●●●●●
10. 228399576 c.92G>A p.C31Y missense 0.00002335●●●●●●
11. 228399584 c.100G>A p.V34M missense 0.00001160●●●●●●
12. 228399602 c.118C>A p.Q40K missense 0.00002324●●●●●●
13. 228399603 c.119A>G p.Q40R missense 0.00001163●●●●●●
14. 228399614 c.130G>A p.E44K missense 0.00001181●●●●●●
15. 228399619 c.135G>C p.K45N missense 0.00027750●●●●●●
16. 228399632 c.148G>A p.V50M missense 0.00001330●●●●●●
17. 228399633 c.149T>G p.V50G missense 0.00001331●●●●●●
18. 228399641 c.157G>A p.G53S missense 0.00001422●●●●●●
19. 228399644 c.160G>A p.A54T missense 0.00001464●●●●●●
20. 228399653 c.169C>T p.R57C missense 0.00001534●●●●●●
21. 228399654 c.170G>A p.R57H missense 0.00001551●●●●●●
22. 228399657 c.173T>G p.L58R missense 0.00006308●●●●●●
23. 228399660 c.176C>T p.A59V missense 0.00001655●●●●●●
24. 228399669 c.185G>A p.G62D missense 0.00003556●●●●●●
25. 228399671 c.187G>A p.D63N missense 0.01725738●●●●●●
26. 228399680 c.196C>A p.R66S missense 0.00004069●●●●●●
27. 228399680 c.196C>T p.R66C missense 0.00002034●●●●●●
28. 228399695 c.211G>T p.D71Y missense 0.00002377●●●●●●
29. 228399722 c.238T>C p.Y80H missense 0.00003299●●●●●●
30. 228399735 c.251C>A p.A84E missense 0.00004224●●●●●●
31. 228399752 c.268G>A p.E90K missense 0.00010139●●●●●●
32. 228399756 c.272C>A p.A91D missense 0.00005297●●●●●●
33. 228399786 c.302C>T p.A101V missense 0.00007678●●●●●●
34. 228399806 c.322C>G p.Q108E missense 0.00008440●●●●●●
35. 228399812 c.328C>G p.P110A missense 0.00008557●●●●●●
36. 228399851 c.367G>A p.E123K missense 0.00065641●●●●●●
37. 228399870 c.386T>A p.F129Y missense 0.00188929●●●●●●
38. 228399871 c.387C>A p.F129L missense 0.00189107●●●●●●
39. 228399873 c.389G>A p.R130H missense 0.00009455●●●●●●
40. 228399960 c.476G>A p.R159H missense 0.00019654●●●●●●
41. 228399977 c.493G>A p.E165K missense 0.00010075●●●●●●
42. 228399980 c.496G>A p.A166T missense 0.00020350●●●●●●
43. 228400179 c.695C>T p.A232V missense 0.00008868●●●●●●
44. 228400187 c.703G>A p.A235T missense 0.00001541●●●●●●
45. 228400190 c.706C>T p.P236S missense 0.00002780●●●●●●
46. 228400190 c.706C>G p.P236A missense 0.00006950●●●●●●
47. 228400193 c.709G>A p.A237T missense 0.00002568●●●●●●
48. 228400194 c.710C>G p.A237G missense 0.00001242●●●●●●
49. 228400211 c.727G>C p.G243R missense 0.00105639●●●●●●
50. 228400215 c.731C>T p.T244M missense 0.00007748●●●●●●
51. 228400250 c.766C>T p.R256C missense 0.00000890●●●●●●
52. 228400280 c.796A>G p.K266E missense 0.00004352●●●●●●
53. 228400286 c.802G>A p.E268K missense 0.00000868●●●●●●
54. 228400297 c.813G>T p.W271C missense 0.00000863●●●●●●
55. 228400313 c.829C>G p.L277V missense 0.00000859●●●●●●
56. 228400319 c.835A>G p.T279A missense 0.00000859●●●●●●
57. 228400326 c.842G>A p.G281D missense 0.00000858●●●●●●
58. 228400331 c.847C>A p.R283S missense 0.00001716●●●●●●
59. 228400337 c.853G>A p.V285M missense 0.00000857●●●●●●
60. 228400344 c.860A>G p.Y287C missense 0.00001714●●●●●●
61. 228400346 c.862G>A p.E288K missense 0.00000857●●●●●●
62. 228400359 c.875A>G p.E292G missense 0.00000856●●●●●●
63. 228400375 c.891G>C p.K297N missense 0.00000857●●●●●●
64. 228400378 c.894C>G p.I298M missense 0.00000858●●●●●●
65. 228400379 c.895C>G p.L299V missense 0.00000858●●●●●●
66. 228400384 c.900C>G p.F300L missense 0.00000859●●●●●●
67. 228400394 c.910T>G p.S304A missense 0.00000867●●●●●●
68. 228400397 c.913G>C p.D305H missense 0.00000869●●●●●●
69. 228400399 c.915C>G p.D305E missense 0.00000871●●●●●●
70. 228400400 c.916C>T p.R306C missense 0.00001745●●●●●●
71. 228400415 c.931T>A p.C311S missense 0.00000902●●●●●●
72. 228400433 c.949G>A p.V317M missense 0.00002888●●●●●●
73. 228400443 c.959C>T p.T320I missense 0.00003023●●●●●●
74. 228400443 c.959C>G p.T320S missense 0.00001008●●●●●●
75. 228400446 c.962A>G p.Y321C missense 0.00009226●●●●●●
76. 228400449 c.965G>T p.S322I missense 0.00002100●●●●●●
77. 228400463 c.979G>T p.V327L missense 0.00006076●●●●●●
78. 228400472 c.988G>C p.E330Q missense 0.00001317●●●●●●
79. 228400472 c.988G>A p.E330K missense 0.00001317●●●●●●
80. 228401156 c.1003T>C p.F335L missense 0.00004032●●●●●●
81. 228401165 c.1012C>T p.R338W missense 0.00003828●●●●●●
82. 228401177 c.1024C>A p.L342M missense 0.00003492●●●●●●
83. 228401178 c.1025T>G p.L342R missense 0.00003462●●●●●●
84. 228401183 c.1030G>C p.V344L missense 0.00150845●●●●●●
85. 228401186 c.1033C>G p.R345G missense 0.00003301●●●●●●
86. 228401205 c.1052C>T p.T351M missense 0.00002880●●●●●●
87. 228401211 c.1058T>C p.L353P missense 0.00002779●●●●●●
88. 228401211 c.1058T>A p.L353Q missense 0.00002779●●●●●●
89. 228401226 c.1073A>T p.Q358L missense 0.00010190●●●●●●
90. 228401229 c.1076C>G p.P359R missense 0.00002499●●●●●●
91. 228401243 c.1090G>T p.A364S missense 0.00004551●●●●●●
92. 228401247 c.1094G>C p.W365S missense 0.00002200●●●●●●
93. 228401262 c.1109C>A p.T370K missense 0.00002050●●●●●●
94. 228401265 c.1112G>T p.R371L missense 0.00014204●●●●●●
95. 228401265 c.1112G>C p.R371P missense 0.00002029●●●●●●
96. 228401279 c.1126G>A p.A376T missense 0.00001961●●●●●●
97. 228401301 c.1148A>G p.E383G missense 0.00004165●●●●●●
98. 228401312 c.1159C>A p.R387S missense 0.00004521●●●●●●
99. 228401313 c.1160G>A p.R387H missense 0.00006788●●●●●●
100. 228401328 c.1175G>A p.R392H missense 0.00023603●●●●●●
101. 228401328 c.1175G>C p.R392P missense 0.00002623●●●●●●
102. 228401331 c.1178A>C p.N393T missense 0.00002682●●●●●●
103. 228401352 c.1199C>T p.A400V missense 0.00004266●●●●●●
104. 228401372 c.1219C>G p.P407A missense 0.00005942●●●●●●
105. 228401388 c.1235C>A p.T412K missense 0.00007241●●●●●●
106. 228401880 c.1264C>T p.L422F missense 0.00001729●●●●●●
107. 228401880 c.1264C>G p.L422V missense 0.00001729●●●●●●
108. 228401896 c.1280C>T p.P427L missense 0.00000861●●●●●●
109. 228401899 c.1283G>A p.R428Q missense 0.00000860●●●●●●
110. 228401905 c.1289C>T p.T430M missense 0.00000858●●●●●●
111. 228401940 c.1324G>C p.V442L missense 0.00085127●●●●●●
112. 228401967 c.1351G>A p.V451I missense 0.00012779●●●●●●
113. 228401971 c.1355A>G p.H452R missense 0.00000852●●●●●●
114. 228401980 c.1364G>A p.R455Q missense 0.00009374●●●●●●
115. 228402001 c.1385C>T p.A462V missense 0.00000858●●●●●●
116. 228402019 c.1403T>C p.I468T missense 0.00000848●●●●●●
117. 228402024 c.1408G>T p.A470S missense 0.00000847●●●●●●
118. 228402025 c.1409C>T p.A470V missense 0.00001693●●●●●●
119. 228402028 c.1412A>G p.E471G missense 0.00000845●●●●●●
120. 228402048 c.1432A>G p.T478A missense 0.00001671●●●●●●
121. 228402049 c.1433C>T p.T478I missense 0.00000836●●●●●●
122. 228402063 c.1447T>C p.C483R missense 0.00003341●●●●●●
123. 228402065 c.1449C>G p.C483W missense 0.00000835●●●●●●
124. 228402073 c.1457A>T p.D486V missense 0.00000835●●●●●●
125. 228402084 c.1468G>T p.V490L missense 0.00000835●●●●●●
126. 228402084 c.1468G>A p.V490M missense 0.00000835●●●●●●
127. 228402090 c.1474T>G p.F492V missense 0.00000836●●●●●●
128. 228402121 c.1505A>G p.Q502R missense 0.65386413●●●●●●
129. 228402121 c.1505A>C p.Q502P missense 0.00000835●●●●●●
130. 228402123 c.1507T>G p.F503V missense 0.00000836●●●●●●
131. 228402126 c.1510T>G p.C504G missense 0.00001672●●●●●●
132. 228402129 c.1513G>A p.V505M missense 0.00021747●●●●●●
133. 228402132 c.1516T>G p.S506A missense 0.00000836●●●●●●
134. 228402133 c.1517C>T p.S506L missense 0.00020912●●●●●●
135. 228402494 c.1523C>G p.P508R missense 0.00007448●●●●●●
136. 228402506 c.1535C>T p.P512L missense 0.00000986●●●●●●
137. 228402515 c.1544C>A p.P515H missense 0.00000885●●●●●●
138. 228402525 c.1554T>G p.D518E missense 0.00000877●●●●●●
139. 228402529 c.1558G>C p.V520L missense 0.00000875●●●●●●
140. 228402529 c.1558G>A p.V520M missense 0.00000875●●●●●●
141. 228402541 c.1570A>G p.R524G missense 0.00000868●●●●●●
142. 228402554 c.1583C>A p.S528Y missense 0.00000865●●●●●●
143. 228402556 c.1585G>A p.V529M missense 0.00001728●●●●●●
144. 228402572 c.1601C>T p.S534F missense 0.00000860●●●●●●
145. 228402584 c.1613A>C p.H538P missense 0.00005995●●●●●●
146. 228402592 c.1621C>T p.R541C missense 0.00006843●●●●●●
147. 228402593 c.1622G>A p.R541H missense 0.00001711●●●●●●
148. 228402604 c.1633A>G p.I545V missense 0.00001706●●●●●●
149. 228402610 c.1639G>A p.G547S missense 0.00001705●●●●●●
150. 228402614 c.1643A>G p.Y548C missense 0.00000851●●●●●●
151. 228402631 c.1660A>C p.K554Q missense 0.00001700●●●●●●
152. 228402632 c.1661A>G p.K554R missense 0.00000850●●●●●●
153. 228402634 c.1663C>T p.L555F missense 0.00001701●●●●●●
154. 228402637 c.1666G>T p.G556C missense 0.00000850●●●●●●
155. 228402647 c.1676C>T p.T559I missense 0.00000849●●●●●●
156. 228402664 c.1693G>A p.E565K missense 0.00002546●●●●●●
157. 228402668 c.1697C>T p.A566V missense 0.00000848●●●●●●
158. 228402676 c.1705G>A p.V569M missense 0.00000848●●●●●●
159. 228402680 c.1709C>T p.A570V missense 0.00000849●●●●●●
160. 228402685 c.1714C>T p.P572S missense 0.00012729●●●●●●
161. 228402690 c.1719G>T p.E573D missense 0.00000850●●●●●●
162. 228402691 c.1720C>G p.L574V missense 0.00001700●●●●●●
163. 228402691 c.1720C>A p.L574M missense 0.00000850●●●●●●
164. 228402706 c.1735G>A p.V579M missense 0.00000851●●●●●●
165. 228402710 c.1739C>T p.A580V missense 0.00003408●●●●●●
166. 228402724 c.1753T>G p.F585V missense 0.00000851●●●●●●
167. 228402728 c.1757A>G p.Q586R missense 0.00000851●●●●●●
168. 228402737 c.1766T>G p.V589G missense 0.00000851●●●●●●
169. 228402740 c.1769C>T p.S590F missense 0.00012765●●●●●●
170. 228402745 c.1774C>T p.L592F missense 0.00041687●●●●●●
171. 228402755 c.1784T>A p.F595Y missense 0.00002554●●●●●●
172. 228402782 c.1811C>T p.P604L missense 0.00000871●●●●●●
173. 228402787 c.1816A>T p.T606S missense 0.00000875●●●●●●
174. 228402799 c.1828G>T p.A610S missense 0.00000894●●●●●●
175. 228403278 c.1843G>A p.V615M missense 0.00006337●●●●●●
176. 228403284 c.1849A>C p.T617P missense 0.00003044●●●●●●
177. 228403296 c.1861G>A p.A621T missense 0.00002885●●●●●●
178. 228403297 c.1862C>T p.A621V missense 0.00002870●●●●●●
179. 228403305 c.1870G>A p.A624T missense 0.00002708●●●●●●
180. 228403305 c.1870G>T p.A624S missense 0.00002708●●●●●●
181. 228403320 c.1885G>A p.E629K missense 0.00002443●●●●●●
182. 228403326 c.1891A>G p.T631A missense 0.00013753●●●●●●
183. 228403345 c.1910C>T p.T637M missense 0.00001960●●●●●●
184. 228403357 c.1922C>T p.A641V missense 0.00007032●●●●●●
185. 228403360 c.1925G>T p.G642V missense 0.00160160●●●●●●
186. 228403382 c.1947G>C p.Q649H missense 0.00001448●●●●●●
187. 228403398 c.1963A>G p.S655G missense 0.00002714●●●●●●
188. 228403399 c.1964G>A p.S655N missense 0.00001353●●●●●●
189. 228403405 c.1970A>G p.Y657C missense 0.00003994●●●●●●
190. 228403405 c.1970A>T p.Y657F missense 0.00001331●●●●●●
191. 228403422 c.1987C>T p.R663C missense 0.00003901●●●●●●
192. 228403423 c.1988G>A p.R663H missense 0.00001300●●●●●●
193. 228403426 c.1991C>T p.T664I missense 0.00001280●●●●●●
194. 228403428 c.1993C>T p.R665W missense 0.00007689●●●●●●
195. 228403429 c.1994G>A p.R665Q missense 0.00016555●●●●●●
196. 228403435 c.2000C>T p.T667M missense 0.00006299●●●●●●
197. 228403437 c.2002C>A p.L668I missense 0.00002497●●●●●●
198. 228403446 c.2011C>T p.R671W missense 0.00019643●●●●●●
199. 228403447 c.2012G>A p.R671Q missense 0.00021860●●●●●●
200. 228403455 c.2020C>A p.P674T missense 0.00001187●●●●●●
201. 228403458 c.2023G>A p.A675T missense 0.00001186●●●●●●
202. 228403468 c.2033A>G p.H678R missense 0.00001118●●●●●●
203. 228403470 c.2035G>A p.G679R missense 0.00001114●●●●●●
204. 228403473 c.2038G>A p.A680T missense 0.00001101●●●●●●
205. 228403474 c.2039C>T p.A680V missense 0.00002200●●●●●●
206. 228403476 c.2041C>G p.Q681E missense 0.00009790●●●●●●
207. 228403485 c.2050T>C p.F684L missense 0.00033130●●●●●●
208. 228403488 c.2053G>C p.V685L missense 0.00001067●●●●●●
209. 228403492 c.2057C>G p.A686G missense 0.00001063●●●●●●
210. 228403494 c.2059A>G p.N687D missense 0.00001061●●●●●●
211. 228403498 c.2063G>T p.G688V missense 0.00001063●●●●●●
212. 228403503 c.2068G>A p.E690K missense 0.00001062●●●●●●
213. 228403507 c.2072G>A p.S691N missense 0.00001072●●●●●●
214. 228403515 c.2080C>T p.R694W missense 0.00002178●●●●●●
215. 228403516 c.2081G>A p.R694Q missense 0.00008721●●●●●●
216. 228403527 c.2092C>T p.R698W missense 0.00001136●●●●●●
217. 228403528 c.2093G>C p.R698P missense 0.00001145●●●●●●
218. 228403528 c.2093G>A p.R698Q missense 0.00002289●●●●●●
219. 228404122 c.2096C>T p.A699V missense 0.00008781●●●●●●
220. 228404139 c.2113G>A p.A705T missense 0.00007462●●●●●●
221. 228404157 c.2131G>A p.A711T missense 0.00007024●●●●●●
222. 228404169 c.2143G>A p.E715K missense 0.00100698●●●●●●
223. 228404172 c.2146G>A p.V716M missense 0.00006693●●●●●●
224. 228404178 c.2152G>A p.A718T missense 0.00013172●●●●●●
225. 228404190 c.2164G>A p.E722K missense 0.00018664●●●●●●
226. 228404200 c.2174A>G p.Q725R missense 0.00005662●●●●●●
227. 228404223 c.2197C>G p.Q733E missense 0.00004853●●●●●●
228. 228404227 c.2201C>G p.A734G missense 0.00004675●●●●●●
229. 228404239 c.2213C>T p.T738M missense 0.00004139●●●●●●
230. 228404266 c.2240C>T p.S747F missense 0.00003383●●●●●●
231. 228404269 c.2243C>T p.P748L missense 0.00003324●●●●●●
232. 228404271 c.2245G>T p.G749C missense 0.00016474●●●●●●
233. 228404278 c.2252A>G p.K751R missense 0.00003246●●●●●●
234. 228404291 c.2265G>C p.Q755H missense 0.00016292●●●●●●
235. 228404292 c.2266G>A p.A756T missense 0.00012993●●●●●●
236. 228404296 c.2270C>T p.S757L missense 0.00023301●●●●●●
237. 228404301 c.2275G>A p.G759R missense 0.00003225●●●●●●
238. 228404304 c.2278C>T p.R760W missense 0.00003278●●●●●●
239. 228404305 c.2279G>A p.R760Q missense 0.01216921●●●●●●
240. 228404307 c.2281C>T p.R761W missense 0.00026123●●●●●●
241. 228404308 c.2282G>A p.R761Q missense 0.00009723●●●●●●
242. 228404313 c.2287C>A p.L763I missense 0.00003270●●●●●●
243. 228404316 c.2290C>T p.L764F missense 0.00003279●●●●●●
244. 228404323 c.2297G>T p.R766L missense 0.00003304●●●●●●
245. 228404323 c.2297G>C p.R766P missense 0.00003304●●●●●●
246. 228404323 c.2297G>A p.R766Q missense 0.00003304●●●●●●
247. 228404335 c.2309G>A p.R770Q missense 0.00064661●●●●●●
248. 228404340 c.2314G>A p.D772N missense 0.00006906●●●●●●
249. 228404352 c.2326T>A p.Y776N missense 0.00003415●●●●●●
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332. 228412307 c.2801C>T p.S934L missense 0.00002485●●●●●●
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342. 228412395 c.2889G>T p.E963D missense 0.00000837●●●●●●
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347. 228412411 c.2905C>T p.L969F missense 0.00000852●●●●●●
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353. 228430902 c.2948C>T p.A983V missense 0.00000929●●●●●●
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355. 228430907 c.2953G>T p.D985Y missense 0.00000911●●●●●●
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360. 228430941 c.2987C>T p.A996V missense 0.00000921●●●●●●
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366. 228430967 c.3013G>A p.E1005K missense 0.00014050●●●●●●
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381. 228431063 c.3109C>T p.R1037W missense 0.00011626●●●●●●
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487. 228434274 c.3803T>A p.V1268E missense 0.00000828●●●●●●
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490. 228434277 c.3806G>A p.R1269Q missense 0.00042237●●●●●●
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492. 228434289 c.3818G>A p.G1273E missense 0.00000833●●●●●●
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502. 228434352 c.3881A>T p.D1294V missense 0.00000828●●●●●●
503. 228434367 c.3896G>C p.S1299T missense 0.00001656●●●●●●
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505. 228434370 c.3899C>T p.S1300F missense 0.00000828●●●●●●
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507. 228434384 c.3913C>T p.R1305C missense 0.00004968●●●●●●
508. 228434385 c.3914G>A p.R1305H missense 0.00004140●●●●●●
509. 228434394 c.3923C>T p.A1308V missense 0.00000828●●●●●●
510. 228434396 c.3925G>A p.A1309T missense 0.00000828●●●●●●
511. 228434397 c.3926C>T p.A1309V missense 0.00015759●●●●●●
512. 228434402 c.3931T>C p.C1311R missense 0.00000830●●●●●●
513. 228434405 c.3934A>G p.M1312V missense 0.00002489●●●●●●
514. 228434406 c.3935T>C p.M1312T missense 0.00000830●●●●●●
515. 228434408 c.3937C>T p.R1313W missense 0.00004143●●●●●●
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517. 228434420 c.3949G>T p.V1317L missense 0.00001657●●●●●●
518. 228434425 c.3954G>T p.Q1318H missense 0.00001660●●●●●●
519. 228434441 c.3970G>C p.D1324H missense 0.00001657●●●●●●
520. 228434453 c.3982T>A p.Y1328N missense 0.00001657●●●●●●
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524. 228434472 c.4001G>A p.G1334D missense 0.00008348●●●●●●
525. 228434477 c.4006C>T p.R1336W missense 0.00016741●●●●●●
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527. 228434481 c.4010T>C p.L1337P missense 0.00000839●●●●●●
528. 228434489 c.4018C>T p.H1340Y missense 0.00008431●●●●●●
529. 228434490 c.4019A>C p.H1340P missense 0.00005063●●●●●●
530. 228434498 c.4027G>A p.V1343I missense 0.00001698●●●●●●
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533. 228437674 c.4042G>A p.A1348T missense 0.00000830●●●●●●
534. 228437675 c.4043C>T p.A1348V missense 0.00014945●●●●●●
535. 228437699 c.4067C>A p.A1356E missense 0.00000830●●●●●●
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538. 228437705 c.4073G>A p.R1358K missense 0.00000830●●●●●●
539. 228437717 c.4085C>T p.A1362V missense 0.00036541●●●●●●
540. 228437719 c.4087G>A p.E1363K missense 0.00000834●●●●●●
541. 228437738 c.4106C>T p.T1369M missense 0.00004980●●●●●●
542. 228437740 c.4108C>A p.L1370M missense 0.00000830●●●●●●
543. 228437741 c.4109T>C p.L1370P missense 0.00000830●●●●●●
544. 228437747 c.4115G>A p.C1372Y missense 0.00001659●●●●●●
545. 228437749 c.4117G>A p.E1373K missense 0.00124461●●●●●●
546. 228437761 c.4129G>A p.A1377T missense 0.00000829●●●●●●
547. 228437773 c.4141G>A p.V1381M missense 0.00000829●●●●●●
548. 228437777 c.4145C>T p.T1382M missense 0.00009117●●●●●●
549. 228437787 c.4155G>C p.K1385N missense 0.00000829●●●●●●
550. 228437792 c.4160G>A p.G1387E missense 0.00000829●●●●●●
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552. 228437813 c.4181C>T p.S1394L missense 0.00004142●●●●●●
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554. 228437818 c.4186G>A p.V1396I missense 0.00001657●●●●●●
555. 228437822 c.4190G>A p.R1397Q missense 0.00001657●●●●●●
556. 228437845 c.4213C>T p.R1405W missense 0.00004973●●●●●●
557. 228437846 c.4214G>A p.R1405Q missense 0.00084539●●●●●●
558. 228437848 c.4216A>G p.R1406G missense 0.00003315●●●●●●
559. 228437851 c.4219C>G p.L1407V missense 0.00050557●●●●●●
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561. 228437866 c.4234G>A p.A1412T missense 0.00000829●●●●●●
562. 228437866 c.4234G>T p.A1412S missense 0.00000829●●●●●●
563. 228437875 c.4243G>A p.A1415T missense 0.00000829●●●●●●
564. 228437876 c.4244C>T p.A1415V missense 0.00013263●●●●●●
565. 228437884 c.4252G>A p.G1418R missense 0.00002487●●●●●●
566. 228437898 c.4266C>G p.C1422W missense 0.00000830●●●●●●
567. 228437899 c.4267G>A p.E1423K missense 0.00000830●●●●●●
568. 228437905 c.4273G>A p.G1425R missense 0.00001661●●●●●●
569. 228437914 c.4282C>T p.R1428W missense 0.00001663●●●●●●
570. 228437915 c.4283G>A p.R1428Q missense 0.00001663●●●●●●
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572. 228437927 c.4295G>T p.S1432I missense 0.00000834●●●●●●
573. 228437935 c.4303G>A p.V1435M missense 0.00000837●●●●●●
574. 228444360 c.4318G>A p.V1440M missense 0.00002487●●●●●●
575. 228444364 c.4322T>C p.V1441A missense 0.00000829●●●●●●
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578. 228444385 c.4343T>C p.V1448A missense 0.00528872●●●●●●
579. 228444407 c.4365G>T p.Q1455H missense 0.00000831●●●●●●
580. 228444426 c.4384C>T p.L1462F missense 0.00000830●●●●●●
581. 228444433 c.4391G>T p.C1464F missense 0.00000830●●●●●●
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583. 228444435 c.4393G>A p.E1465K missense 0.00001660●●●●●●
584. 228444453 c.4411A>C p.T1471P missense 0.00000829●●●●●●
585. 228444454 c.4412C>T p.T1471M missense 0.00009951●●●●●●
586. 228444477 c.4435G>A p.G1479R missense 0.00004144●●●●●●
587. 228444487 c.4445T>C p.L1482P missense 0.00001657●●●●●●
588. 228444495 c.4453A>G p.S1485G missense 0.00011602●●●●●●
589. 228444496 c.4454G>C p.S1485T missense 0.00005802●●●●●●
590. 228444498 c.4456T>C p.S1486P missense 0.00000829●●●●●●
591. 228444499 c.4457C>T p.S1486L missense 0.00003315●●●●●●
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593. 228444507 c.4465C>T p.R1489C missense 0.00000829●●●●●●
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597. 228444519 c.4477G>T p.V1493L missense 0.00014092●●●●●●
598. 228444531 c.4489C>T p.R1497W missense 0.00002487●●●●●●
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602. 228444562 c.4520C>T p.A1507V missense 0.00012451●●●●●●
603. 228444565 c.4523T>A p.V1508D missense 1.00000000●●●●●●
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607. 228444585 c.4543G>A p.E1515K missense 0.00004155●●●●●●
608. 228444589 c.4547C>T p.A1516V missense 0.00015797●●●●●●
609. 228444600 c.4558C>T p.R1520W missense 0.00016645●●●●●●
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611. 228444603 c.4561C>T p.L1521F missense 0.00000833●●●●●●
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615. 228444621 c.4579G>A p.V1527M missense 0.00001676●●●●●●
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621. 228451853 c.4622G>T p.S1541I missense 0.00000830●●●●●●
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626. 228451889 c.4658C>T p.T1553M missense 0.00001662●●●●●●
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629. 228451907 c.4676C>T p.A1559V missense 0.00004152●●●●●●
630. 228451928 c.4697C>T p.T1566M missense 0.00000830●●●●●●
631. 228451933 c.4702T>C p.Y1568H missense 0.00000829●●●●●●
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634. 228451964 c.4733C>T p.S1578L missense 0.00001659●●●●●●
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642. 228451994 c.4763C>T p.T1588I missense 0.00000831●●●●●●
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645. 228452016 c.4785G>C p.E1595D missense 0.01367652●●●●●●
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647. 228452027 c.4796C>T p.A1599V missense 0.00001665●●●●●●
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795. 228462357 c.5768C>T p.S1923F missense 0.00001967●●●●●●
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798. 228462386 c.5797C>T p.R1933W missense 0.00000973●●●●●●
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810. 228462495 c.5906C>T p.T1969I missense 0.00003167●●●●●●
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814. 228462512 c.5923G>A p.A1975T missense 0.00001107●●●●●●
815. 228462513 c.5924C>T p.A1975V missense 0.00002218●●●●●●
816. 228462515 c.5926T>C p.S1976P missense 0.00002236●●●●●●
817. 228462521 c.5932T>C p.S1978P missense 0.00002285●●●●●●
818. 228462524 c.5935G>A p.A1979T missense 0.00004619●●●●●●
819. 228462536 c.5947G>T p.V1983F missense 0.00001216●●●●●●
820. 228462540 c.5951G>A p.R1984Q missense 0.00004972●●●●●●
821. 228463487 c.5980C>G p.L1994V missense 0.00004542●●●●●●
822. 228463490 c.5983G>A p.E1995K missense 0.00008420●●●●●●
823. 228463493 c.5986C>T p.P1996S missense 0.00003984●●●●●●
824. 228463508 c.6001G>A p.E2001K missense 0.00002563●●●●●●
825. 228463518 c.6011C>T p.S2004L missense 0.00002037●●●●●●
826. 228463527 c.6020T>A p.L2007Q missense 0.00001676●●●●●●
827. 228463529 c.6022G>A p.E2008K missense 0.00004848●●●●●●
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829. 228463533 c.6026T>G p.V2009G missense 0.00003079●●●●●●
830. 228463535 c.6028G>A p.E2010K missense 0.00008945●●●●●●
831. 228463539 c.6032T>C p.L2011P missense 0.00001417●●●●●●
832. 228463542 c.6035C>T p.T2012M missense 0.00001361●●●●●●
833. 228463544 c.6037C>T p.R2013W missense 0.00001330●●●●●●
834. 228463548 c.6041C>A p.P2014Q missense 0.00067244●●●●●●
835. 228463578 c.6071C>T p.A2024V missense 0.00044684●●●●●●
836. 228463584 c.6077C>T p.A2026V missense 0.00002010●●●●●●
837. 228463590 c.6083C>T p.A2028V missense 0.00001975●●●●●●
838. 228463592 c.6085C>T p.P2029S missense 0.00001964●●●●●●
839. 228463593 c.6086C>T p.P2029L missense 0.00001965●●●●●●
840. 228463596 c.6089G>A p.G2030E missense 0.00001946●●●●●●
841. 228463598 c.6091A>C p.K2031Q missense 0.00000970●●●●●●
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848. 228463662 c.6155C>T p.A2052V missense 0.00005363●●●●●●
849. 228463664 c.6157G>A p.D2053N missense 0.00001355●●●●●●
850. 228463667 c.6160C>T p.R2054C missense 0.00011338●●●●●●
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852. 228463674 c.6167T>G p.F2056C missense 0.00001606●●●●●●
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855. 228463680 c.6173G>T p.G2058V missense 0.00061046●●●●●●
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940. 228464972 c.6712G>T p.D2238Y missense 0.00000904●●●●●●
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963. 228465542 c.6842C>T p.A2281V missense 0.00001680●●●●●●
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972. 228466411 c.6881G>A p.R2294H missense 0.00003361●●●●●●
973. 228466419 c.6889C>T p.R2297W missense 0.00002508●●●●●●
974. 228466420 c.6890G>A p.R2297Q missense 0.00002507●●●●●●
975. 228466428 c.6898A>T p.I2300F missense 0.00000834●●●●●●
976. 228466438 c.6908A>G p.E2303G missense 0.00001667●●●●●●
977. 228466446 c.6916C>A p.R2306S missense 0.00000833●●●●●●
978. 228466447 c.6917G>A p.R2306H missense 0.00000833●●●●●●
979. 228466449 c.6919G>A p.G2307S missense 0.00001667●●●●●●
980. 228466452 c.6922G>A p.V2308M missense 0.00000833●●●●●●
981. 228466473 c.6943C>T p.R2315W missense 0.00009173●●●●●●
982. 228466474 c.6944G>A p.R2315Q missense 0.00000834●●●●●●
983. 228466482 c.6952G>A p.A2318T missense 0.00000834●●●●●●
984. 228466483 c.6953C>T p.A2318V missense 0.00000834●●●●●●
985. 228466491 c.6961C>G p.R2321G missense 0.00000834●●●●●●
986. 228466491 c.6961C>T p.R2321W missense 0.00000834●●●●●●
987. 228466492 c.6962G>A p.R2321Q missense 0.00011674●●●●●●
988. 228466524 c.6994G>A p.G2332R missense 0.00020845●●●●●●
989. 228466527 c.6997C>T p.P2333S missense 0.00000833●●●●●●
990. 228466530 c.7000A>G p.K2334E missense 0.00001667●●●●●●
991. 228466542 c.7012G>A p.V2338I missense 0.00000833●●●●●●
992. 228466545 c.7015A>G p.S2339G missense 0.00000833●●●●●●
993. 228466546 c.7016G>T p.S2339I missense 0.00000833●●●●●●
994. 228466560 c.7030C>T p.R2344C missense 0.00000832●●●●●●
995. 228466561 c.7031G>A p.R2344H missense 0.00000833●●●●●●
996. 228466561 c.7031G>T p.R2344L missense 0.00000833●●●●●●
997. 228466576 c.7046G>A p.S2349N missense 0.00000831●●●●●●
998. 228466587 c.7057G>A p.A2353T missense 0.00000831●●●●●●
999. 228466593 c.7063G>A p.D2355N missense 0.00000831●●●●●●
1000. 228466596 c.7066G>A p.E2356K missense 0.00001662●●●●●●
1001. 228466600 c.7070A>G p.D2357G missense 0.00000831●●●●●●
1002. 228466603 c.7073C>T p.T2358I missense 0.00000831●●●●●●
1003. 228466612 c.7082G>A p.C2361Y missense 0.00005815●●●●●●
1004. 228466617 c.7087G>A p.A2363T missense 0.00000831●●●●●●
1005. 228466620 c.7090G>A p.G2364S missense 0.00004985●●●●●●
1006. 228466633 c.7103C>T p.T2368I missense 0.00000831●●●●●●
1007. 228466650 c.7120G>A p.V2374M missense 0.00007494●●●●●●
1008. 228466878 c.7129C>G p.Q2377E missense 0.00002562●●●●●●
1009. 228466888 c.7139C>G p.T2380S missense 0.00000849●●●●●●
1010. 228466897 c.7148G>A p.R2383Q missense 0.00003378●●●●●●
1011. 228466906 c.7157A>G p.Q2386R missense 0.00000841●●●●●●
1012. 228466926 c.7177C>T p.P2393S missense 0.00000837●●●●●●
1013. 228466927 c.7178C>G p.P2393R missense 0.00001674●●●●●●
1014. 228466929 c.7180G>A p.A2394T missense 0.00020909●●●●●●
1015. 228466932 c.7183C>T p.P2395S missense 0.00003343●●●●●●
1016. 228466947 c.7198T>G p.C2400G missense 0.00000834●●●●●●
1017. 228466950 c.7201G>A p.E2401K missense 0.00000834●●●●●●
1018. 228466971 c.7222C>T p.R2408W missense 0.00000834●●●●●●
1019. 228466972 c.7223G>A p.R2408Q missense 0.00000833●●●●●●
1020. 228466974 c.7225C>T p.P2409S missense 0.00000833●●●●●●
1021. 228466977 c.7228C>T p.P2410S missense 0.00004167●●●●●●
1022. 228466999 c.7250C>T p.T2417M missense 0.00010000●●●●●●
1023. 228467001 c.7252G>A p.V2418M missense 0.00000833●●●●●●
1024. 228467013 c.7264G>C p.G2422R missense 0.00000835●●●●●●
1025. 228467014 c.7265G>A p.G2422E missense 0.00003336●●●●●●
1026. 228467014 c.7265G>C p.G2422A missense 0.00005839●●●●●●
1027. 228467014 c.7265G>T p.G2422V missense 0.00003336●●●●●●
1028. 228467020 c.7271A>T p.N2424I missense 0.00000834●●●●●●
1029. 228467022 c.7273G>A p.V2425M missense 0.00001669●●●●●●
1030. 228467032 c.7283A>G p.E2428G missense 0.00000835●●●●●●
1031. 228467040 c.7291G>A p.G2431S missense 0.00000836●●●●●●
1032. 228467044 c.7295C>T p.T2432M missense 0.00000837●●●●●●
1033. 228467049 c.7300C>T p.H2434Y missense 0.00003348●●●●●●
1034. 228467052 c.7303C>T p.R2435W missense 0.00002512●●●●●●
1035. 228467053 c.7304G>A p.R2435Q missense 0.00002514●●●●●●
1036. 228467064 c.7315C>T p.R2439W missense 0.00018489●●●●●●
1037. 228467065 c.7316G>A p.R2439Q missense 0.00003362●●●●●●
1038. 228467067 c.7318C>T p.R2440W missense 0.00001681●●●●●●
1039. 228467068 c.7319G>A p.R2440Q missense 0.00003363●●●●●●
1040. 228467077 c.7328C>G p.S2443C missense 0.00000843●●●●●●
1041. 228467079 c.7330A>T p.T2444S missense 0.00099521●●●●●●
1042. 228467085 c.7336A>T p.T2446S missense 0.00000845●●●●●●
1043. 228467091 c.7342C>A p.P2448T missense 0.00000846●●●●●●
1044. 228467094 c.7345G>A p.V2449M missense 0.00000848●●●●●●
1045. 228467095 c.7346T>C p.V2449A missense 0.00518855●●●●●●
1046. 228467106 c.7357G>A p.V2453I missense 0.00017110●●●●●●
1047. 228467116 c.7367C>T p.S2456L missense 0.00000867●●●●●●
1048. 228467118 c.7369C>T p.R2457C missense 0.00000871●●●●●●
1049. 228467119 c.7370G>A p.R2457H missense 0.00013075●●●●●●
1050. 228467122 c.7373C>T p.S2458F missense 0.00000879●●●●●●
1051. 228467130 c.7381C>T p.R2461C missense 0.00077998●●●●●●
1052. 228467131 c.7382G>A p.R2461H missense 0.00002665●●●●●●
1053. 228467524 c.7399A>G p.I2467V missense 0.00003473●●●●●●
1054. 228467530 c.7405G>A p.V2469I missense 0.00003440●●●●●●
1055. 228467537 c.7412T>G p.L2471R missense 0.00001745●●●●●●
1056. 228467540 c.7415C>G p.T2472R missense 0.00003509●●●●●●
1057. 228467542 c.7417C>T p.R2473W missense 0.00007061●●●●●●
1058. 228467542 c.7417C>G p.R2473G missense 0.00001765●●●●●●
1059. 228467546 c.7421C>T p.P2474L missense 0.00008917●●●●●●
1060. 228467566 c.7441C>T p.R2481C missense 0.00005910●●●●●●
1061. 228467582 c.7457T>C p.V2486A missense 0.00004361●●●●●●
1062. 228467602 c.7477C>T p.R2493W missense 0.00012119●●●●●●
1063. 228467611 c.7486C>T p.P2496S missense 0.00007299●●●●●●
1064. 228467617 c.7492G>T p.A2498S missense 0.00004880●●●●●●
1065. 228467642 c.7517C>T p.T2506M missense 0.00016719●●●●●●
1066. 228467644 c.7519C>T p.P2507S missense 0.00002379●●●●●●
1067. 228467645 c.7520C>T p.P2507L missense 0.00004759●●●●●●
1068. 228467647 c.7522C>G p.L2508V missense 0.00002377●●●●●●
1069. 228467650 c.7525T>C p.S2509P missense 0.00002347●●●●●●
1070. 228467653 c.7528C>G p.P2510A missense 0.00002334●●●●●●
1071. 228467654 c.7529C>T p.P2510L missense 0.00004660●●●●●●
1072. 228467657 c.7532C>T p.S2511F missense 0.00002315●●●●●●
1073. 228467662 c.7537A>G p.K2513E missense 0.00002289●●●●●●
1074. 228467689 c.7564A>T p.M2522L missense 0.00002055●●●●●●
1075. 228467698 c.7573C>G p.L2525V missense 0.00001957●●●●●●
1076. 228467701 c.7576C>T p.R2526C missense 0.00003835●●●●●●
1077. 228467702 c.7577G>C p.R2526P missense 0.00026457●●●●●●
1078. 228467707 c.7582C>T p.L2528F missense 0.00001780●●●●●●
1079. 228467710 c.7585C>T p.R2529W missense 0.00003484●●●●●●
1080. 228467711 c.7586G>A p.R2529Q missense 0.07466675●●●●●●
1081. 228467722 c.7597G>A p.A2533T missense 0.00001418●●●●●●
1082. 228467732 c.7607G>T p.G2536V missense 0.00001299●●●●●●
1083. 228467734 c.7609G>T p.V2537F missense 0.00001278●●●●●●
1084. 228467740 c.7615C>T p.R2539W missense 0.00002428●●●●●●
1085. 228467741 c.7616G>A p.R2539Q missense 0.00003568●●●●●●
1086. 228467756 c.7631G>T p.S2544I missense 0.00001021●●●●●●
1087. 228467756 c.7631G>A p.S2544N missense 0.00001021●●●●●●
1088. 228467765 c.7640G>T p.S2547I missense 0.00002876●●●●●●
1089. 228467880 c.7664C>T p.A2555V missense 0.00002515●●●●●●
1090. 228467882 c.7666C>T p.R2556W missense 0.00007545●●●●●●
1091. 228467883 c.7667G>A p.R2556Q missense 0.00010053●●●●●●
1092. 228467883 c.7667G>T p.R2556L missense 0.00001676●●●●●●
1093. 228467900 c.7684G>C p.G2562R missense 0.00000837●●●●●●
1094. 228467904 c.7688C>T p.P2563L missense 0.00004187●●●●●●
1095. 228467912 c.7696G>T p.D2566Y missense 0.00002513●●●●●●
1096. 228467916 c.7700C>T p.A2567V missense 0.00000838●●●●●●
1097. 228467921 c.7705G>A p.A2569T missense 0.00002516●●●●●●
1098. 228467925 c.7709C>T p.T2570M missense 0.00002518●●●●●●
1099. 228467927 c.7711G>A p.E2571K missense 0.00000840●●●●●●
1100. 228467928 c.7712A>G p.E2571G missense 0.00000840●●●●●●
1101. 228467945 c.7729T>G p.F2577V missense 0.00001689●●●●●●
1102. 228467963 c.7747C>T p.H2583Y missense 0.00000867●●●●●●
1103. 228467966 c.7750G>A p.E2584K missense 0.00000881●●●●●●
1104. 228467969 c.7753G>C p.D2585H missense 0.00082799●●●●●●
1105. 228467969 c.7753G>A p.D2585N missense 0.00000881●●●●●●
1106. 228467978 c.7762G>A p.V2588I missense 0.00000942●●●●●●
1107. 228467981 c.7765G>A p.E2589K missense 0.00001897●●●●●●
1108. 228467994 c.7778A>G p.N2593S missense 0.00036576●●●●●●
1109. 228467996 c.7780G>A p.G2594R missense 0.00006356●●●●●●
1110. 228467999 c.7783A>T p.M2595L missense 0.00002173●●●●●●
1111. 228468001 c.7785G>A p.M2595I missense 0.00001095●●●●●●
1112. 228468014 c.7798G>A p.D2600N missense 0.00001235●●●●●●
1113. 228468030 c.7814T>G p.I2605S missense 0.00001366●●●●●●
1114. 228468037 c.7821C>A p.H2607Q missense 0.00001516●●●●●●
1115. 228468042 c.7826G>C p.G2609A missense 0.00001558●●●●●●
1116. 228468044 c.7828C>T p.R2610W missense 0.00001639●●●●●●
1117. 228468047 c.7831C>T p.R2611C missense 0.00003327●●●●●●
1118. 228468048 c.7832G>A p.R2611H missense 0.00006791●●●●●●
1119. 228468054 c.7838C>T p.T2613M missense 0.00001754●●●●●●
1120. 228468069 c.7853G>A p.S2618N missense 0.01319654●●●●●●
1121. 228468072 c.7856T>C p.I2619T missense 0.00003873●●●●●●
1122. 228468077 c.7861C>T p.R2621W missense 0.00006247●●●●●●
1123. 228468078 c.7862G>A p.R2621Q missense 0.00012428●●●●●●
1124. 228468078 c.7862G>T p.R2621L missense 0.00002071●●●●●●
1125. 228468087 c.7871C>A p.A2624E missense 0.00002108●●●●●●
1126. 228468093 c.7877T>A p.I2626K missense 0.00002116●●●●●●
1127. 228468098 c.7882C>T p.R2628C missense 0.00008553●●●●●●
1128. 228468099 c.7883G>A p.R2628H missense 0.00002128●●●●●●
1129. 228468102 c.7886C>T p.A2629V missense 0.00010574●●●●●●
1130. 228468104 c.7888T>G p.S2630A missense 0.00040019●●●●●●
1131. 228468114 c.7898A>G p.K2633R missense 0.00002062●●●●●●
1132. 228468132 c.7916G>A p.R2639H missense 0.00001914●●●●●●
1133. 228468144 c.7928G>A p.R2643Q missense 0.00042178●●●●●●
1134. 228468236 c.7936C>T p.P2646S missense 0.00000857●●●●●●
1135. 228468242 c.7942G>T p.V2648L missense 0.00003387●●●●●●
1136. 228468255 c.7955C>T p.A2652V missense 0.00000838●●●●●●
1137. 228468260 c.7960G>A p.D2654N missense 0.00000836●●●●●●
1138. 228468272 c.7972G>A p.A2658T missense 0.00000834●●●●●●
1139. 228468281 c.7981C>T p.R2661C missense 0.00002497●●●●●●
1140. 228468282 c.7982G>A p.R2661H missense 0.00005826●●●●●●
1141. 228468285 c.7985G>A p.G2662D missense 0.00001664●●●●●●
1142. 228468294 c.7994C>A p.A2665D missense 0.00000831●●●●●●
1143. 228468307 c.8007A>T p.E2669D missense 0.00005817●●●●●●
1144. 228468311 c.8011T>C p.S2671P missense 0.00003325●●●●●●
1145. 228468317 c.8017C>A p.P2673T missense 0.00000831●●●●●●
1146. 228468320 c.8020G>A p.E2674K missense 0.00001662●●●●●●
1147. 228468324 c.8024C>T p.A2675V missense 0.00000831●●●●●●
1148. 228468327 c.8027A>G p.H2676R missense 0.00000831●●●●●●
1149. 228468338 c.8038C>T p.R2680C missense 0.00003327●●●●●●
1150. 228468339 c.8039G>A p.R2680H missense 0.00003327●●●●●●
1151. 228468350 c.8050G>A p.V2684M missense 0.00000833●●●●●●
1152. 228468357 c.8057T>C p.L2686P missense 0.00000833●●●●●●
1153. 228468362 c.8062C>G p.P2688A missense 0.00000834●●●●●●
1154. 228468365 c.8065A>G p.S2689G missense 0.00001668●●●●●●
1155. 228468371 c.8071A>C p.K2691Q missense 0.00000834●●●●●●
1156. 228468378 c.8078A>T p.D2693V missense 0.00000836●●●●●●
1157. 228468381 c.8081T>A p.F2694Y missense 0.00000837●●●●●●
1158. 228468389 c.8089A>C p.T2697P missense 0.00000841●●●●●●
1159. 228468390 c.8090C>T p.T2697M missense 0.00013455●●●●●●
1160. 228468393 c.8093C>T p.A2698V missense 0.00002529●●●●●●
1161. 228468399 c.8099C>T p.T2700M missense 0.00004229●●●●●●
1162. 228468401 c.8101C>T p.R2701W missense 0.00001692●●●●●●
1163. 228468402 c.8102G>A p.R2701Q missense 0.00004233●●●●●●
1164. 228468405 c.8105G>A p.G2702E missense 0.00008471●●●●●●
1165. 228468410 c.8110G>A p.V2704M missense 0.00001698●●●●●●
1166. 228468420 c.8120A>C p.D2707A missense 0.00000852●●●●●●
1167. 228468422 c.8122G>A p.V2708M missense 0.00001705●●●●●●
1168. 228468426 c.8126G>A p.S2709N missense 0.00001708●●●●●●
1169. 228468432 c.8132A>C p.E2711A missense 0.00000860●●●●●●
1170. 228468437 c.8137G>A p.A2713T missense 0.00100537●●●●●●
1171. 228468440 c.8140G>A p.G2714S missense 0.00013002●●●●●●
1172. 228468440 c.8140G>C p.G2714R missense 0.00024270●●●●●●
1173. 228468440 c.8140G>T p.G2714C missense 0.00000867●●●●●●
1174. 228468455 c.8155C>T p.H2719Y missense 0.00000876●●●●●●
1175. 228468458 c.8158G>A p.V2720M missense 0.30041062●●●●●●
1176. 228468467 c.8167G>A p.E2723K missense 0.00001825●●●●●●
1177. 228468476 c.8176C>T p.R2726W missense 0.00000937●●●●●●
1178. 228468479 c.8179G>A p.A2727T missense 0.00000958●●●●●●
1179. 228468482 c.8182C>T p.R2728W missense 0.00000963●●●●●●
1180. 228468483 c.8183G>A p.R2728Q missense 0.00026175●●●●●●
1181. 228468488 c.8188C>T p.R2730C missense 0.00000981●●●●●●
1182. 228468489 c.8189G>A p.R2730H missense 0.00000984●●●●●●
1183. 228468491 c.8191G>A p.V2731M missense 0.00003967●●●●●●
1184. 228468497 c.8197G>A p.D2733N missense 0.00001003●●●●●●
1185. 228469642 c.8206G>A p.V2736M missense 0.00007700●●●●●●
1186. 228469645 c.8209G>A p.G2737S missense 0.00001702●●●●●●
1187. 228469646 c.8210G>A p.G2737D missense 0.00000850●●●●●●
1188. 228469648 c.8212A>G p.I2738V missense 0.00001694●●●●●●
1189. 228469652 c.8216C>G p.T2739S missense 0.00002529●●●●●●
1190. 228469654 c.8218A>C p.K2740Q missense 0.00000841●●●●●●
1191. 228469669 c.8233A>G p.M2745V missense 0.00001667●●●●●●
1192. 228469674 c.8238G>T p.E2746D missense 0.00001666●●●●●●
1193. 228469679 c.8243T>C p.L2748P missense 0.00000832●●●●●●
1194. 228469687 c.8251G>A p.E2751K missense 0.00000832●●●●●●
1195. 228469688 c.8252A>G p.E2751G missense 0.00000832●●●●●●
1196. 228469705 c.8269T>C p.C2757R missense 0.00001665●●●●●●
1197. 228469706 c.8270G>A p.C2757Y missense 0.00000832●●●●●●
1198. 228469708 c.8272G>A p.V2758I missense 0.00000833●●●●●●
1199. 228469720 c.8284G>A p.E2762K missense 0.00001669●●●●●●
1200. 228469723 c.8287A>C p.S2763R missense 0.00006679●●●●●●
1201. 228469731 c.8295C>G p.S2765R missense 0.00001672●●●●●●
1202. 228469731 c.8295C>A p.S2765R missense 0.00000836●●●●●●
1203. 228469732 c.8296G>A p.D2766N missense 0.00001672●●●●●●
1204. 228469742 c.8306T>C p.M2769T missense 0.00014234●●●●●●
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1206. 228469753 c.8317G>A p.G2773S missense 0.00001681●●●●●●
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1475. 228475981 c.10031G>T p.C3344F missense 0.00000833●●●●●●
1476. 228476008 c.10058C>T p.A3353V missense 0.00000840●●●●●●
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1480. 228476025 c.10075C>T p.P3359S missense 0.00004250●●●●●●
1481. 228476337 c.10087C>T p.H3363Y missense 0.00002486●●●●●●
1482. 228476353 c.10103T>G p.L3368R missense 0.00000828●●●●●●
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1486. 228476386 c.10136C>T p.A3379V missense 0.00000828●●●●●●
1487. 228476389 c.10139C>T p.T3380M missense 0.00011594●●●●●●
1488. 228476394 c.10144C>T p.R3382W missense 0.00007453●●●●●●
1489. 228476395 c.10145G>A p.R3382Q missense 0.00002484●●●●●●
1490. 228476413 c.10163C>T p.A3388V missense 0.00001656●●●●●●
1491. 228476416 c.10166C>T p.A3389V missense 0.00001656●●●●●●
1492. 228476421 c.10171G>A p.V3391M missense 0.00008281●●●●●●
1493. 228476437 c.10187G>T p.G3396V missense 0.00000828●●●●●●
1494. 228476439 c.10189C>T p.R3397C missense 0.00028984●●●●●●
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1497. 228476466 c.10216C>T p.H3406Y missense 0.00002484●●●●●●
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1504. 228476535 c.10285G>A p.E3429K missense 0.00000828●●●●●●
1505. 228476542 c.10292C>T p.S3431F missense 0.00000828●●●●●●
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1513. 228479607 c.10348G>C p.A3450P missense 0.00000857●●●●●●
1514. 228479623 c.10364G>T p.G3455V missense 0.00000838●●●●●●
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1516. 228479629 c.10370G>A p.R3457K missense 0.00000836●●●●●●
1517. 228479640 c.10381G>T p.A3461S missense 0.00000832●●●●●●
1518. 228479643 c.10384G>A p.V3462M missense 0.00001662●●●●●●
1519. 228479662 c.10403T>C p.M3468T missense 0.00000829●●●●●●
1520. 228479676 c.10417C>G p.L3473V missense 0.00003316●●●●●●
1521. 228479677 c.10418T>C p.L3473P missense 0.00000829●●●●●●
1522. 228479680 c.10421G>A p.S3474N missense 0.00003315●●●●●●
1523. 228479681 c.10422C>A p.S3474R missense 0.00001658●●●●●●
1524. 228479688 c.10429G>T p.A3477S missense 0.00000829●●●●●●
1525. 228479706 c.10447A>G p.K3483E missense 0.00002486●●●●●●
1526. 228479707 c.10448A>C p.K3483T missense 0.00000829●●●●●●
1527. 228479715 c.10456G>A p.E3486K missense 0.00002486●●●●●●
1528. 228479725 c.10466G>C p.R3489T missense 0.00003314●●●●●●
1529. 228479740 c.10481A>G p.Y3494C missense 0.00003313●●●●●●
1530. 228479749 c.10490G>A p.R3497K missense 0.00001656●●●●●●
1531. 228479764 c.10505G>A p.R3502K missense 0.00006625●●●●●●
1532. 228479797 c.10538C>T p.A3513V missense 0.00001656●●●●●●
1533. 228479802 c.10543G>A p.A3515T missense 0.00044710●●●●●●
1534. 228479805 c.10546G>A p.G3516R missense 0.00027322●●●●●●
1535. 228479808 c.10549G>A p.E3517K missense 0.00467800●●●●●●
1536. 228479818 c.10559G>A p.C3520Y missense 0.00000828●●●●●●
1537. 228479826 c.10567G>A p.G3523R missense 0.00001656●●●●●●
1538. 228479839 c.10580C>A p.T3527N missense 0.00000828●●●●●●
1539. 228479842 c.10583C>T p.S3528L missense 0.00000828●●●●●●
1540. 228479848 c.10589C>T p.T3530M missense 0.00017386●●●●●●
1541. 228479858 c.10599C>G p.I3533M missense 0.00001656●●●●●●
1542. 228480239 c.10619T>G p.F3540C missense 0.00001660●●●●●●
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1544. 228480245 c.10625A>C p.E3542A missense 0.00001659●●●●●●
1545. 228480250 c.10630G>T p.V3544L missense 0.00000829●●●●●●
1546. 228480256 c.10636A>C p.N3546H missense 0.00000829●●●●●●
1547. 228480281 c.10661C>T p.T3554I missense 0.00000828●●●●●●
1548. 228480283 c.10663G>A p.A3555T missense 0.00000828●●●●●●
1549. 228480286 c.10666G>T p.V3556L missense 0.00000828●●●●●●
1550. 228480286 c.10666G>C p.V3556L missense 0.00001656●●●●●●
1551. 228480307 c.10687A>C p.S3563R missense 0.00000828●●●●●●
1552. 228480317 c.10697C>T p.P3566L missense 0.00231018●●●●●●
1553. 228480319 c.10699G>C p.V3567L missense 0.00156496●●●●●●
1554. 228480322 c.10702G>A p.E3568K missense 0.00000828●●●●●●
1555. 228480325 c.10705T>C p.W3569R missense 0.00004968●●●●●●
1556. 228480332 c.10712A>G p.K3571R missense 0.00001656●●●●●●
1557. 228480333 c.10713G>C p.K3571N missense 0.00000828●●●●●●
1558. 228480335 c.10715G>T p.G3572V missense 0.00004140●●●●●●
1559. 228480350 c.10730G>A p.R3577K missense 0.00000828●●●●●●
1560. 228480374 c.10754G>A p.R3585K missense 0.00001656●●●●●●
1561. 228480382 c.10762G>A p.G3588R missense 0.00006624●●●●●●
1562. 228480392 c.10772G>A p.C3591Y missense 0.00000828●●●●●●
1563. 228480406 c.10786C>T p.R3596C missense 0.00000828●●●●●●
1564. 228480407 c.10787G>A p.R3596H missense 0.00000828●●●●●●
1565. 228480416 c.10796C>T p.A3599V missense 0.00000828●●●●●●
1566. 228480424 c.10804G>A p.D3602N missense 0.00000828●●●●●●
1567. 228480427 c.10807A>G p.T3603A missense 0.00000828●●●●●●
1568. 228480440 c.10820C>T p.S3607L missense 0.00004140●●●●●●
1569. 228480443 c.10823G>T p.C3608F missense 0.00000828●●●●●●
1570. 228480445 c.10825G>A p.V3609M missense 0.00004140●●●●●●
1571. 228480451 c.10831G>A p.G3611R missense 0.00000828●●●●●●
1572. 228480457 c.10837G>A p.E3613K missense 0.00000828●●●●●●
1573. 228480467 c.10847C>T p.S3616L missense 0.00006624●●●●●●
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1575. 228480472 c.10852A>G p.M3618V missense 0.00000828●●●●●●
1576. 228480473 c.10853T>C p.M3618T missense 0.00000828●●●●●●
1577. 228480481 c.10861G>A p.V3621I missense 0.00004140●●●●●●
1578. 228480481 c.10861G>C p.V3621L missense 0.00001656●●●●●●
1579. 228480482 c.10862T>G p.V3621G missense 0.00000828●●●●●●
1580. 228481060 c.10874C>G p.P3625R missense 0.00000839●●●●●●
1581. 228481062 c.10876A>G p.I3626V missense 0.00000838●●●●●●
1582. 228481067 c.10881G>C p.K3627N missense 0.00472266●●●●●●
1583. 228481078 c.10892G>T p.G3631V missense 0.00001666●●●●●●
1584. 228481084 c.10898G>A p.R3633K missense 0.00034110●●●●●●
1585. 228481089 c.10903G>A p.E3635K missense 0.00000831●●●●●●
1586. 228481095 c.10909G>A p.A3637T missense 0.00000830●●●●●●
1587. 228481105 c.10919G>A p.G3640E missense 0.00000829●●●●●●
1588. 228481111 c.10925C>T p.T3642I missense 0.00000829●●●●●●
1589. 228481116 c.10930G>A p.V3644M missense 0.00007461●●●●●●
1590. 228481123 c.10937G>A p.R3646Q missense 0.00005802●●●●●●
1591. 228481123 c.10937G>T p.R3646L missense 0.00000829●●●●●●
1592. 228481135 c.10949G>A p.S3650N missense 0.00000829●●●●●●
1593. 228481136 c.10950C>A p.S3650R missense 0.00008286●●●●●●
1594. 228481141 c.10955T>C p.M3652T missense 0.00000829●●●●●●
1595. 228481143 c.10957G>C p.A3653P missense 0.00001657●●●●●●
1596. 228481146 c.10960C>T p.P3654S missense 0.00002486●●●●●●
1597. 228481149 c.10963G>A p.V3655M missense 0.00004142●●●●●●
1598. 228481196 c.11010C>A p.H3670Q missense 0.00012423●●●●●●
1599. 228481201 c.11015T>A p.L3672Q missense 0.00000828●●●●●●
1600. 228481206 c.11020C>A p.Q3674K missense 0.00000828●●●●●●
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1602. 228481212 c.11026G>A p.G3676R missense 0.00004141●●●●●●
1603. 228481218 c.11032A>T p.R3678W missense 0.00000828●●●●●●
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1605. 228481236 c.11050C>T p.R3684C missense 0.00027331●●●●●●
1606. 228481236 c.11050C>A p.R3684S missense 0.00000828●●●●●●
1607. 228481237 c.11051G>A p.R3684H missense 0.00004141●●●●●●
1608. 228481242 c.11056C>T p.L3686F missense 0.00001656●●●●●●
1609. 228481245 c.11059G>A p.V3687M missense 0.00004970●●●●●●
1610. 228481248 c.11062G>A p.A3688T missense 0.00000828●●●●●●
1611. 228481257 c.11071G>A p.A3691T missense 0.00017400●●●●●●
1612. 228481258 c.11072C>T p.A3691V missense 0.00001657●●●●●●
1613. 228481275 c.11089A>G p.M3697V missense 0.00000830●●●●●●
1614. 228481281 c.11095G>A p.G3699R missense 0.00004160●●●●●●
1615. 228481293 c.11107A>G p.T3703A missense 0.00000836●●●●●●
1616. 228481299 c.11113G>T p.A3705S missense 0.00001679●●●●●●
1617. 228481303 c.11117T>C p.M3706T missense 0.00000842●●●●●●
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1621. 228481315 c.11129G>C p.R3710T missense 0.00003406●●●●●●
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1623. 228481858 c.11137C>T p.P3713S missense 0.00000828●●●●●●
1624. 228481870 c.11149A>G p.I3717V missense 0.00000828●●●●●●
1625. 228481888 c.11167G>A p.E3723K missense 0.00000828●●●●●●
1626. 228481897 c.11176A>C p.T3726P missense 0.01281733●●●●●●
1627. 228481912 c.11191G>A p.A3731T missense 0.00000828●●●●●●
1628. 228481915 c.11194A>G p.T3732A missense 0.00000828●●●●●●
1629. 228481916 c.11195C>T p.T3732M missense 0.00002484●●●●●●
1630. 228481916 c.11195C>A p.T3732K missense 0.00000828●●●●●●
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1632. 228481921 c.11200T>C p.W3734R missense 0.00000828●●●●●●
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1634. 228481929 c.11208G>T p.E3736D missense 0.00001656●●●●●●
1635. 228481940 c.11219C>T p.A3740V missense 0.00003312●●●●●●
1636. 228481946 c.11225C>T p.P3742L missense 0.00003312●●●●●●
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1641. 228481992 c.11271A>T p.R3757S missense 0.00000828●●●●●●
1642. 228481997 c.11276G>T p.S3759I missense 0.00000828●●●●●●
1643. 228482031 c.11310G>C p.Q3770H missense 0.00000828●●●●●●
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1646. 228482044 c.11323G>T p.A3775S missense 0.00002483●●●●●●
1647. 228482057 c.11336C>T p.A3779V missense 0.00000828●●●●●●
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1649. 228482066 c.11345A>C p.Y3782S missense 0.00000828●●●●●●
1650. 228482068 c.11347T>C p.S3783P missense 0.00099333●●●●●●
1651. 228482069 c.11348C>T p.S3783L missense 0.00000828●●●●●●
1652. 228482072 c.11351G>A p.C3784Y missense 0.00000828●●●●●●
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1657. 228482102 c.11381C>T p.T3794I missense 0.00000828●●●●●●
1658. 228482111 c.11390T>C p.V3797A missense 0.00000828●●●●●●
1659. 228482505 c.11420A>T p.D3807V missense 0.00000831●●●●●●
1660. 228482516 c.11431C>A p.Q3811K missense 0.00000830●●●●●●
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1662. 228482538 c.11453C>T p.T3818M missense 0.00009947●●●●●●
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1665. 228482557 c.11472G>C p.E3824D missense 0.00000828●●●●●●
1666. 228482568 c.11483C>T p.A3828V missense 0.00001656●●●●●●
1667. 228482576 c.11491G>A p.V3831M missense 0.00001656●●●●●●
1668. 228482581 c.11496G>C p.E3832D missense 0.00003312●●●●●●
1669. 228482592 c.11507G>T p.G3836V missense 0.00001656●●●●●●
1670. 228482604 c.11519T>A p.L3840H missense 0.00000828●●●●●●
1671. 228482632 c.11547G>T p.R3849S missense 0.00000828●●●●●●
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1673. 228482663 c.11578C>A p.H3860N missense 0.00000828●●●●●●
1674. 228482679 c.11594C>A p.A3865E missense 0.00000828●●●●●●
1675. 228482690 c.11605G>A p.E3869K missense 0.00000828●●●●●●
1676. 228482701 c.11616T>G p.C3872W missense 0.00002484●●●●●●
1677. 228482708 c.11623G>A p.G3875R missense 0.00003312●●●●●●
1678. 228482718 c.11633G>A p.R3878K missense 0.00000828●●●●●●
1679. 228482723 c.11638T>C p.S3880P missense 0.00000828●●●●●●
1680. 228482724 c.11639C>T p.S3880L missense 0.00001656●●●●●●
1681. 228482730 c.11645C>T p.T3882I missense 0.00001656●●●●●●
1682. 228482738 c.11653G>A p.V3885I missense 0.00007451●●●●●●
1683. 228482744 c.11659G>A p.A3887T missense 0.00000828●●●●●●
1684. 228494089 c.11676C>G p.F3892L missense 0.00002706●●●●●●
1685. 228494090 c.11677C>T p.R3893W missense 0.00008085●●●●●●
1686. 228494091 c.11678G>A p.R3893Q missense 0.00001326●●●●●●
1687. 228494097 c.11684C>T p.P3895L missense 0.00053350●●●●●●
1688. 228494097 c.11684C>G p.P3895R missense 0.00001270●●●●●●
1689. 228494115 c.11702C>T p.A3901V missense 0.00003412●●●●●●
1690. 228494118 c.11705A>C p.E3902A missense 0.00001097●●●●●●
1691. 228494124 c.11711G>C p.G3904A missense 0.00001067●●●●●●
1692. 228494130 c.11717C>T p.T3906M missense 0.00001030●●●●●●
1693. 228494132 c.11719G>A p.A3907T missense 0.00001008●●●●●●
1694. 228494133 c.11720C>A p.A3907D missense 0.00000999●●●●●●
1695. 228494143 c.11730G>C p.Q3910H missense 0.00000940●●●●●●
1696. 228494144 c.11731T>G p.C3911G missense 0.00045890●●●●●●
1697. 228494145 c.11732G>A p.C3911Y missense 0.00007471●●●●●●
1698. 228494159 c.11746C>T p.P3916S missense 0.00000907●●●●●●
1699. 228494163 c.11750C>T p.T3917I missense 0.00035054●●●●●●
1700. 228494163 c.11750C>A p.T3917N missense 0.00014381●●●●●●
1701. 228494181 c.11768G>C p.S3923T missense 0.00001768●●●●●●
1702. 228494189 c.11776G>A p.G3926S missense 0.00000880●●●●●●
1703. 228494198 c.11785C>A p.L3929M missense 0.00001750●●●●●●
1704. 228494205 c.11792C>T p.A3931V missense 0.00000873●●●●●●
1705. 228494208 c.11795A>G p.N3932S missense 0.00018296●●●●●●
1706. 228494213 c.11800C>T p.R3934C missense 0.00002610●●●●●●
1707. 228494214 c.11801G>T p.R3934L missense 0.00000869●●●●●●
1708. 228494214 c.11801G>A p.R3934H missense 0.00004343●●●●●●
1709. 228494216 c.11803C>T p.R3935W missense 0.00151063●●●●●●
1710. 228494222 c.11809C>G p.P3937A missense 0.00002584●●●●●●
1711. 228494225 c.11812C>T p.R3938W missense 0.00002581●●●●●●
1712. 228494237 c.11824T>G p.C3942G missense 0.00002569●●●●●●
1713. 228494243 c.11830G>A p.A3944T missense 0.00030771●●●●●●
1714. 228494243 c.11830G>T p.A3944S missense 0.00002564●●●●●●
1715. 228494244 c.11831C>T p.A3944V missense 0.00006836●●●●●●
1716. 228494252 c.11839G>C p.V3947L missense 0.00000851●●●●●●
1717. 228494264 c.11851C>G p.L3951V missense 0.00000851●●●●●●
1718. 228494270 c.11857C>T p.R3953C missense 0.00004261●●●●●●
1719. 228494271 c.11858G>A p.R3953H missense 0.00003409●●●●●●
1720. 228494271 c.11858G>C p.R3953P missense 0.00000852●●●●●●
1721. 228494278 c.11865C>G p.D3955E missense 0.00000855●●●●●●
1722. 228494279 c.11866A>C p.T3956P missense 0.00000857●●●●●●
1723. 228494285 c.11872G>A p.E3958K missense 0.00000862●●●●●●
1724. 228494288 c.11875T>C p.Y3959H missense 0.00000863●●●●●●
1725. 228494301 c.11888G>A p.C3963Y missense 0.00001761●●●●●●
1726. 228494304 c.11891G>T p.G3964V missense 0.00000882●●●●●●
1727. 228494319 c.11906G>A p.S3969N missense 0.00007181●●●●●●
1728. 228494321 c.11908G>A p.A3970T missense 0.00000901●●●●●●
1729. 228494327 c.11914C>T p.L3972F missense 0.00000908●●●●●●
1730. 228494327 c.11914C>G p.L3972V missense 0.00000908●●●●●●
1731. 228494331 c.11918C>G p.T3973S missense 0.00000912●●●●●●
1732. 228494605 c.11930C>T p.A3977V missense 0.00005496●●●●●●
1733. 228494607 c.11932C>A p.P3978T missense 0.00088940●●●●●●
1734. 228494611 c.11936T>C p.V3979A missense 0.00004955●●●●●●
1735. 228494613 c.11938C>T p.R3980W missense 0.00004912●●●●●●
1736. 228494623 c.11948G>A p.R3983Q missense 0.00008450●●●●●●
1737. 228494632 c.11957A>C p.Q3986P missense 0.00003805●●●●●●
1738. 228494670 c.11995T>C p.C3999R missense 0.00006656●●●●●●
1739. 228494676 c.12001G>A p.E4001K missense 0.00005983●●●●●●
1740. 228494676 c.12001G>C p.E4001Q missense 0.00003988●●●●●●
1741. 228494685 c.12010C>T p.R4004W missense 0.00010255●●●●●●
1742. 228494686 c.12011G>A p.R4004Q missense 0.00004958●●●●●●
1743. 228494689 c.12014C>T p.A4005V missense 0.00004757●●●●●●
1744. 228494691 c.12016G>T p.G4006C missense 0.00002996●●●●●●
1745. 228494698 c.12023G>A p.S4008N missense 0.00003240●●●●●●
1746. 228494700 c.12025G>A p.V4009M missense 0.00003180●●●●●●
1747. 228494709 c.12034C>T p.R4012C missense 0.00002010●●●●●●
1748. 228494710 c.12035G>A p.R4012H missense 0.00001995●●●●●●
1749. 228494710 c.12035G>T p.R4012L missense 0.00000997●●●●●●
1750. 228494743 c.12068A>T p.K4023M missense 0.00001746●●●●●●
1751. 228494744 c.12069G>T p.K4023N missense 0.00000872●●●●●●
1752. 228494752 c.12077T>G p.M4026R missense 0.00000863●●●●●●
1753. 228494785 c.12110T>C p.V4037A missense 0.00004193●●●●●●
1754. 228494787 c.12112C>T p.R4038C missense 0.00005026●●●●●●
1755. 228494790 c.12115G>A p.G4039R missense 0.40908409●●●●●●
1756. 228494793 c.12118G>A p.V4040M missense 0.00019948●●●●●●
1757. 228494806 c.12131A>G p.D4044G missense 0.00000831●●●●●●
1758. 228494808 c.12133G>A p.A4045T missense 0.00009965●●●●●●
1759. 228494809 c.12134C>T p.A4045V missense 0.00000831●●●●●●
1760. 228494812 c.12137G>T p.G4046V missense 0.00008303●●●●●●
1761. 228494824 c.12149G>T p.C4050F missense 0.00000830●●●●●●
1762. 228494830 c.12155C>T p.T4052M missense 0.00028220●●●●●●
1763. 228494833 c.12158G>A p.G4053D missense 0.00000830●●●●●●
1764. 228494839 c.12164C>T p.T4055M missense 0.00003320●●●●●●
1765. 228494856 c.12181C>T p.L4061F missense 0.00006638●●●●●●
1766. 228494859 c.12184T>C p.S4062P missense 0.00000830●●●●●●
1767. 228494862 c.12187G>A p.V4063I missense 0.00000830●●●●●●
1768. 228494866 c.12191G>T p.R4064L missense 0.00004152●●●●●●
1769. 228494866 c.12191G>A p.R4064H missense 0.00002491●●●●●●
1770. 228494963 c.12197C>T p.P4066L missense 0.00000856●●●●●●
1771. 228494965 c.12199A>G p.R4067G missense 0.00001711●●●●●●
1772. 228494969 c.12203C>T p.P4068L missense 0.00002566●●●●●●
1773. 228494976 c.12210C>G p.F4070L missense 0.00000855●●●●●●
1774. 228494977 c.12211A>G p.K4071E missense 0.00003416●●●●●●
1775. 228494983 c.12217C>T p.R4073W missense 0.00001706●●●●●●
1776. 228494983 c.12217C>G p.R4073G missense 0.00000853●●●●●●
1777. 228494984 c.12218G>A p.R4073Q missense 0.00005112●●●●●●
1778. 228494993 c.12227G>T p.S4076I missense 0.00001699●●●●●●
1779. 228494993 c.12227G>C p.S4076T missense 0.00000849●●●●●●
1780. 228494995 c.12229C>G p.L4077V missense 0.00000849●●●●●●
1781. 228495016 c.12250A>G p.I4084V missense 0.00007567●●●●●●
1782. 228495022 c.12256C>T p.R4086W missense 0.00010061●●●●●●
1783. 228495023 c.12257G>A p.R4086Q missense 0.00004185●●●●●●
1784. 228495053 c.12287C>T p.S4096L missense 0.00005846●●●●●●
1785. 228495056 c.12290G>A p.G4097E missense 0.00000836●●●●●●
1786. 228495061 c.12295G>A p.V4099M missense 0.00008374●●●●●●
1787. 228495064 c.12298G>A p.V4100M missense 0.00000838●●●●●●
1788. 228495077 c.12311A>G p.K4104R missense 0.00000853●●●●●●
1789. 228495082 c.12316G>T p.G4106C missense 0.00000863●●●●●●
1790. 228495098 c.12332C>G p.A4111G missense 0.00000929●●●●●●
1791. 228495098 c.12332C>T p.A4111V missense 0.00000929●●●●●●
1792. 228495107 c.12341A>G p.K4114R missense 0.00000986●●●●●●
1793. 228495107 c.12341A>C p.K4114T missense 0.00000986●●●●●●
1794. 228495112 c.12346G>A p.E4116K missense 0.00062555●●●●●●
1795. 228495118 c.12352C>T p.R4118W missense 0.00003294●●●●●●
1796. 228495119 c.12353G>A p.R4118Q missense 0.00018987●●●●●●
1797. 228495124 c.12358C>A p.Q4120K missense 0.00001164●●●●●●
1798. 228495125 c.12359A>C p.Q4120P missense 0.00002336●●●●●●
1799. 228495130 c.12364G>A p.A4122T missense 0.00005009●●●●●●
1800. 228495130 c.12364G>T p.A4122S missense 0.00001252●●●●●●
1801. 228495134 c.12368C>T p.T4123M missense 0.00001314●●●●●●
1802. 228495136 c.12370C>T p.R4124W missense 0.00001338●●●●●●
1803. 228495137 c.12371G>A p.R4124Q missense 0.00004106●●●●●●
1804. 228495156 c.12390A>T p.Q4130H missense 0.00023667●●●●●●
1805. 228495156 c.12390A>C p.Q4130H missense 0.00001578●●●●●●
1806. 228495157 c.12391C>G p.L4131V missense 0.00020604●●●●●●
1807. 228495169 c.12403G>A p.D4135N missense 0.00001817●●●●●●
1808. 228495173 c.12407C>T p.T4136M missense 0.00015129●●●●●●
1809. 228495178 c.12412G>A p.E4138K missense 0.00002022●●●●●●
1810. 228495199 c.12433G>A p.G4145S missense 0.00004990●●●●●●
1811. 228495211 c.12445G>A p.A4149T missense 0.00008489●●●●●●
1812. 228495225 c.12459G>C p.R4153S missense 0.00003145●●●●●●
1813. 228495226 c.12460G>T p.V4154F missense 0.00053574●●●●●●
1814. 228495821 c.12476T>G p.V4159G missense 0.00032322●●●●●●
1815. 228495832 c.12487C>T p.R4163W missense 0.00009946●●●●●●
1816. 228495833 c.12488G>A p.R4163Q missense 0.00003314●●●●●●
1817. 228495835 c.12490G>A p.G4164R missense 0.00000829●●●●●●
1818. 228495845 c.12500A>T p.D4167V missense 0.00000829●●●●●●
1819. 228495846 c.12501T>G p.D4167E missense 0.00019059●●●●●●
1820. 228495848 c.12503C>G p.A4168G missense 0.00001658●●●●●●
1821. 228495848 c.12503C>T p.A4168V missense 0.00004144●●●●●●
1822. 228495853 c.12508G>T p.V4170L missense 0.00004144●●●●●●
1823. 228495854 c.12509T>C p.V4170A missense 0.00000829●●●●●●
1824. 228495857 c.12512C>T p.T4171M missense 0.00005802●●●●●●
1825. 228495862 c.12517G>A p.D4173N missense 0.00003315●●●●●●
1826. 228495895 c.12550A>G p.R4184G missense 0.00000831●●●●●●
1827. 228495899 c.12554C>A p.A4185D missense 0.00000831●●●●●●
1828. 228495910 c.12565G>T p.G4189C missense 0.00000835●●●●●●
1829. 228495913 c.12568G>A p.V4190M missense 0.00024231●●●●●●
1830. 228495917 c.12572A>G p.Q4191R missense 0.00001675●●●●●●
1831. 228495920 c.12575G>T p.W4192L missense 0.00000839●●●●●●
1832. 228495929 c.12584A>G p.Q4195R missense 0.00001702●●●●●●
1833. 228495931 c.12586G>T p.G4196C missense 0.00000838●●●●●●
1834. 228495934 c.12589C>G p.L4197V missense 0.00000833●●●●●●
1835. 228495944 c.12599A>C p.Q4200P missense 0.00000833●●●●●●
1836. 228495949 c.12604A>G p.N4202D missense 0.00000834●●●●●●
1837. 228495950 c.12605A>G p.N4202S missense 0.00007506●●●●●●
1838. 228495973 c.12628C>T p.R4210W missense 0.00005889●●●●●●
1839. 228495973 c.12628C>G p.R4210G missense 0.00000841●●●●●●
1840. 228495974 c.12629G>A p.R4210Q missense 0.00004206●●●●●●
1841. 228495982 c.12637C>T p.R4213C missense 0.00001691●●●●●●
1842. 228495983 c.12638G>A p.R4213H missense 0.00134602●●●●●●
1843. 228495991 c.12646A>T p.T4216S missense 0.00000856●●●●●●
1844. 228495997 c.12652C>T p.R4218W missense 0.00005215●●●●●●
1845. 228496001 c.12656T>C p.L4219P missense 0.00000892●●●●●●
1846. 228496009 c.12664G>A p.V4222M missense 0.00001863●●●●●●
1847. 228496013 c.12668C>T p.T4223M missense 0.00056414●●●●●●
1848. 228496018 c.12673G>A p.E4225K missense 0.00014634●●●●●●
1849. 228496021 c.12676G>T p.D4226Y missense 0.00040039●●●●●●
1850. 228496024 c.12679G>A p.A4227T missense 0.00003564●●●●●●
1851. 228496024 c.12679G>T p.A4227S missense 0.00004752●●●●●●
1852. 228496052 c.12707A>G p.N4236S missense 0.00001601●●●●●●
1853. 228496055 c.12710A>G p.H4237R missense 0.00001657●●●●●●
1854. 228496066 c.12721G>T p.A4241S missense 0.04025258●●●●●●
1855. 228496075 c.12730A>C p.T4244P missense 0.00016344●●●●●●
1856. 228496078 c.12733G>A p.V4245I missense 0.00014822●●●●●●
1857. 228496800 c.12740C>T p.A4247V missense 0.00001890●●●●●●
1858. 228496815 c.12755T>C p.I4252T missense 0.00001533●●●●●●
1859. 228496831 c.12771G>T p.Q4257H missense 0.00002771●●●●●●
1860. 228496832 c.12772G>T p.D4258Y missense 0.00001383●●●●●●
1861. 228496835 c.12775G>A p.V4259M missense 0.00004225●●●●●●
1862. 228496850 c.12790G>C p.G4264R missense 0.00001460●●●●●●
1863. 228496874 c.12814C>T p.R4272W missense 0.00004823●●●●●●
1864. 228496881 c.12821C>T p.S4274F missense 0.00001663●●●●●●
1865. 228496896 c.12836A>G p.Q4279R missense 0.00003678●●●●●●
1866. 228496904 c.12844C>T p.R4282C missense 0.00001994●●●●●●
1867. 228496905 c.12845G>A p.R4282H missense 0.00105768●●●●●●
1868. 228496914 c.12854T>C p.L4285S missense 0.00002140●●●●●●
1869. 228496917 c.12857G>C p.G4286A missense 0.00002168●●●●●●
1870. 228496938 c.12878A>G p.N4293S missense 0.00002485●●●●●●
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1873. 228496976 c.12916C>T p.H4306Y missense 0.00002950●●●●●●
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1875. 228497189 c.12941C>T p.T4314I missense 0.00023214●●●●●●
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1880. 228497224 c.12976G>C p.G4326R missense 0.00001658●●●●●●
1881. 228497228 c.12980C>T p.T4327M missense 0.00000829●●●●●●
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1884. 228497243 c.12995C>T p.A4332V missense 0.00000829●●●●●●
1885. 228497255 c.13007T>C p.V4336A missense 0.00001660●●●●●●
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1888. 228503557 c.13022C>T p.T4341M missense 0.00009448●●●●●●
1889. 228503565 c.13030C>T p.R4344W missense 0.00024578●●●●●●
1890. 228503566 c.13031G>A p.R4344Q missense 0.01164866●●●●●●
1891. 228503587 c.13052C>T p.A4351V missense 0.00016390●●●●●●
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1895. 228503599 c.13064G>T p.G4355V missense 0.00001184●●●●●●
1896. 228503599 c.13064G>A p.G4355D missense 0.00001184●●●●●●
1897. 228503605 c.13070C>T p.A4357V missense 0.00013105●●●●●●
1898. 228503613 c.13078G>C p.E4360Q missense 0.00001203●●●●●●
1899. 228503613 c.13078G>A p.E4360K missense 0.00001203●●●●●●
1900. 228503643 c.13108G>A p.A4370T missense 0.00011207●●●●●●
1901. 228503664 c.13129G>A p.D4377N missense 0.00003690●●●●●●
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1903. 228503670 c.13135C>A p.P4379T missense 0.00003689●●●●●●
1904. 228503671 c.13136C>T p.P4379L missense 0.00001228●●●●●●
1905. 228503673 c.13138G>C p.V4380L missense 0.00001228●●●●●●
1906. 228503673 c.13138G>A p.V4380M missense 0.00004910●●●●●●
1907. 228503674 c.13139T>C p.V4380A missense 0.00001226●●●●●●
1908. 228503676 c.13141C>T p.H4381Y missense 0.00023338●●●●●●
1909. 228503677 c.13142A>G p.H4381R missense 0.70139015●●●●●●
1910. 228503679 c.13144A>G p.T4382A missense 0.00213348●●●●●●
1911. 228503683 c.13148C>T p.S4383L missense 0.00006170●●●●●●
1912. 228503686 c.13151A>G p.E4384G missense 0.00007767●●●●●●
1913. 228503694 c.13159G>A p.E4387K missense 0.00003216●●●●●●
1914. 228503701 c.13166T>C p.V4389A missense 0.00001674●●●●●●
1915. 228503709 c.13174G>A p.E4392K missense 0.00001774●●●●●●
1916. 228503711 c.13176G>C p.E4392D missense 0.00007181●●●●●●
1917. 228503716 c.13181G>T p.G4394V missense 0.00001906●●●●●●
1918. 228503721 c.13186C>T p.R4396C missense 0.00005974●●●●●●
1919. 228503748 c.13213C>T p.R4405W missense 0.00011750●●●●●●
1920. 228503748 c.13213C>G p.R4405G missense 0.00002350●●●●●●
1921. 228503766 c.13231C>T p.R4411W missense 0.00005206●●●●●●
1922. 228503767 c.13232G>A p.R4411Q missense 0.00010513●●●●●●
1923. 228503788 c.13253A>T p.D4418V missense 0.00002884●●●●●●
1924. 228503802 c.13267G>A p.A4423T missense 0.00034504●●●●●●
1925. 228503802 c.13267G>T p.A4423S missense 0.00006274●●●●●●
1926. 228503809 c.13274T>G p.L4425R missense 0.00003243●●●●●●
1927. 228503818 c.13283G>A p.R4428Q missense 0.00003432●●●●●●
1928. 228504415 c.13291C>T p.R4431C missense 0.00003138●●●●●●
1929. 228504416 c.13292G>A p.R4431H missense 0.00004136●●●●●●
1930. 228504446 c.13322C>T p.A4441V missense 0.00003836●●●●●●
1931. 228504454 c.13330C>T p.R4444W missense 0.00003770●●●●●●
1932. 228504455 c.13331G>A p.R4444Q missense 0.00001881●●●●●●
1933. 228504460 c.13336G>A p.G4446S missense 0.00021485●●●●●●
1934. 228504463 c.13339G>A p.A4447T missense 0.00001860●●●●●●
1935. 228504472 c.13348T>C p.C4450R missense 0.69486042●●●●●●
1936. 228504475 c.13351T>C p.F4451L missense 0.00000942●●●●●●
1937. 228504485 c.13361C>T p.T4454M missense 0.00001955●●●●●●
1938. 228504485 c.13361C>A p.T4454K missense 0.00005866●●●●●●
1939. 228504493 c.13369G>A p.E4457K missense 0.00006029●●●●●●
1940. 228504497 c.13373C>T p.A4458V missense 0.00002041●●●●●●
1941. 228504505 c.13381G>A p.V4461M missense 0.00005258●●●●●●
1942. 228504511 c.13387G>A p.E4463K missense 0.00001090●●●●●●
1943. 228504515 c.13391C>T p.A4464V missense 0.00008902●●●●●●
1944. 228504526 c.13402A>T p.I4468F missense 0.00001189●●●●●●
1945. 228504530 c.13406A>G p.N4469S missense 0.00025920●●●●●●
1946. 228504535 c.13411G>A p.A4471T missense 0.00016607●●●●●●
1947. 228504536 c.13412C>T p.A4471V missense 0.00006449●●●●●●
1948. 228504541 c.13417G>C p.V4473L missense 0.00001355●●●●●●
1949. 228504548 c.13424C>T p.P4475L missense 0.00005912●●●●●●
1950. 228504559 c.13435G>A p.D4479N missense 0.00004892●●●●●●
1951. 228504574 c.13450G>A p.A4484T missense 0.00263691●●●●●●
1952. 228504577 c.13453G>A p.D4485N missense 0.00025868●●●●●●
1953. 228504580 c.13456G>A p.G4486S missense 0.00011065●●●●●●
1954. 228504586 c.13462C>G p.H4488D missense 0.00815087●●●●●●
1955. 228504591 c.13467C>A p.H4489Q missense 0.24437234●●●●●●
1956. 228504592 c.13468G>A p.A4490T missense 0.00052831●●●●●●
1957. 228504599 c.13475T>G p.L4492R missense 0.00010581●●●●●●
1958. 228504604 c.13480C>T p.R4494C missense 0.00008005●●●●●●
1959. 228504614 c.13490A>T p.Q4497L missense 0.00181294●●●●●●
1960. 228504628 c.13504G>A p.G4502R missense 0.00028726●●●●●●
1961. 228504635 c.13511T>C p.V4504A missense 0.00006064●●●●●●
1962. 228504638 c.13514C>T p.T4505I missense 0.00006344●●●●●●
1963. 228504643 c.13519G>A p.A4507T missense 0.00013125●●●●●●
1964. 228504649 c.13525C>T p.R4509C missense 0.00021106●●●●●●
1965. 228504650 c.13526G>A p.R4509H missense 0.00722439●●●●●●
1966. 228504655 c.13531G>A p.A4511T missense 0.00081481●●●●●●
1967. 228504658 c.13534G>A p.V4512M missense 0.00007621●●●●●●
1968. 228504670 c.13546C>T p.R4516W missense 0.42304493●●●●●●
1969. 228505167 c.13564C>T p.L4522F missense 0.00000889●●●●●●
1970. 228505180 c.13577C>T p.P4526L missense 0.00000867●●●●●●
1971. 228505204 c.13601G>A p.R4534H missense 0.26191414●●●●●●
1972. 228505251 c.13648G>A p.G4550R missense 0.00000841●●●●●●
1973. 228505257 c.13654G>A p.G4552S missense 0.00066476●●●●●●
1974. 228505257 c.13654G>T p.G4552C missense 0.00000841●●●●●●
1975. 228505261 c.13658G>A p.G4553D missense 0.00000841●●●●●●
1976. 228505275 c.13672C>T p.R4558C missense 0.00327190●●●●●●
1977. 228505276 c.13673G>A p.R4558H missense 0.00026207●●●●●●
1978. 228505276 c.13673G>T p.R4558L missense 0.00013526●●●●●●
1979. 228505278 c.13675G>A p.V4559M missense 0.00002532●●●●●●
1980. 228505278 c.13675G>T p.V4559L missense 0.00000844●●●●●●
1981. 228505308 c.13705T>C p.W4569R missense 0.00000868●●●●●●
1982. 228505333 c.13730C>G p.P4577R missense 0.00003398●●●●●●
1983. 228505344 c.13741T>G p.C4581G missense 0.00000845●●●●●●
1984. 228505359 c.13756C>A p.L4586M missense 0.00000844●●●●●●
1985. 228505363 c.13760C>A p.A4587D missense 0.00000844●●●●●●
1986. 228505368 c.13765G>A p.G4589R missense 0.00016044●●●●●●
1987. 228505374 c.13771A>T p.T4591S missense 0.00000848●●●●●●
1988. 228505375 c.13772C>G p.T4591S missense 0.00000849●●●●●●
1989. 228505378 c.13775A>G p.Y4592C missense 0.00010185●●●●●●
1990. 228505380 c.13777C>T p.R4593C missense 0.00005094●●●●●●
1991. 228505381 c.13778G>A p.R4593H missense 0.00003399●●●●●●
1992. 228505386 c.13783C>T p.R4595C missense 0.00005956●●●●●●
1993. 228505387 c.13784G>T p.R4595L missense 0.00000851●●●●●●
1994. 228505387 c.13784G>A p.R4595H missense 0.00002552●●●●●●
1995. 228505389 c.13786G>A p.V4596M missense 0.00000852●●●●●●
1996. 228505392 c.13789G>A p.A4597T missense 0.00000852●●●●●●
1997. 228505402 c.13799G>A p.G4600D missense 0.00000854●●●●●●
1998. 228505423 c.13820C>T p.P4607L missense 0.00013698●●●●●●
1999. 228505446 c.13843C>T p.R4615W missense 0.00002581●●●●●●
2000. 228505447 c.13844G>A p.R4615Q missense 0.00003441●●●●●●
2001. 228505601 c.13858C>G p.P4620A missense 0.00000872●●●●●●
2002. 228505602 c.13859C>T p.P4620L missense 0.00000873●●●●●●
2003. 228505611 c.13868T>C p.V4623A missense 0.00003472●●●●●●
2004. 228505629 c.13886C>G p.A4629G missense 0.00002553●●●●●●
2005. 228505631 c.13888C>T p.P4630S missense 0.00000847●●●●●●
2006. 228505634 c.13891G>C p.E4631Q missense 0.00001687●●●●●●
2007. 228505635 c.13892A>C p.E4631A missense 0.00000843●●●●●●
2008. 228505640 c.13897C>T p.R4633W missense 0.00022671●●●●●●
2009. 228505641 c.13898G>A p.R4633Q missense 0.00001676●●●●●●
2010. 228505668 c.13925C>G p.S4642C missense 0.69402762●●●●●●
2011. 228505674 c.13931A>G p.E4644G missense 0.00000828●●●●●●
2012. 228505700 c.13957G>A p.E4653K missense 0.00006626●●●●●●
2013. 228505715 c.13972A>G p.K4658E missense 0.00000828●●●●●●
2014. 228505721 c.13978A>G p.M4660V missense 0.00001657●●●●●●
2015. 228505722 c.13979T>A p.M4660K missense 0.00001657●●●●●●
2016. 228505725 c.13982A>C p.E4661A missense 0.00111827●●●●●●
2017. 228505727 c.13984C>T p.R4662C missense 0.04875381●●●●●●
2018. 228505728 c.13985G>A p.R4662H missense 0.00003314●●●●●●
2019. 228505728 c.13985G>C p.R4662P missense 0.00000828●●●●●●
2020. 228505739 c.13996G>A p.G4666S missense 0.18431694●●●●●●
2021. 228505739 c.13996G>T p.G4666C missense 0.00048890●●●●●●
2022. 228505745 c.14002C>T p.R4668W missense 0.00003314●●●●●●
2023. 228505746 c.14003G>A p.R4668Q missense 0.00003314●●●●●●
2024. 228505751 c.14008G>A p.E4670K missense 0.00001657●●●●●●
2025. 228505760 c.14017T>A p.S4673T missense 0.00001657●●●●●●
2026. 228505767 c.14024G>T p.G4675V missense 0.00000829●●●●●●
2027. 228505769 c.14026C>T p.R4676W missense 0.00007458●●●●●●
2028. 228505770 c.14027G>A p.R4676Q missense 0.00000829●●●●●●
2029. 228505776 c.14033A>C p.Q4678P missense 0.00000829●●●●●●
2030. 228505777 c.14034G>T p.Q4678H missense 0.00001658●●●●●●
2031. 228505781 c.14038C>G p.L4680V missense 0.00000829●●●●●●
2032. 228505788 c.14045T>C p.I4682T missense 0.00000829●●●●●●
2033. 228505851 c.14108G>A p.C4703Y missense 0.00000843●●●●●●
2034. 228505854 c.14111C>T p.P4704L missense 0.00012705●●●●●●
2035. 228505857 c.14114C>T p.A4705V missense 0.00002549●●●●●●
2036. 228505873 c.14130G>C p.Q4710H missense 0.00001758●●●●●●
2037. 228506609 c.14156A>G p.D4719G missense 0.00008297●●●●●●
2038. 228506633 c.14180C>T p.P4727L missense 0.00007055●●●●●●
2039. 228506635 c.14182C>T p.P4728S missense 0.00014023●●●●●●
2040. 228506686 c.14233C>T p.R4745W missense 0.00003370●●●●●●
2041. 228506687 c.14234G>A p.R4745Q missense 0.00097739●●●●●●
2042. 228506695 c.14242C>T p.R4748C missense 0.00014713●●●●●●
2043. 228506696 c.14243G>A p.R4748H missense 0.00023162●●●●●●
2044. 228506700 c.14247G>A p.M4749I missense 0.00002738●●●●●●
2045. 228506701 c.14248A>G p.S4750G missense 0.00002701●●●●●●
2046. 228506704 c.14251C>T p.R4751C missense 0.00005250●●●●●●
2047. 228506704 c.14251C>A p.R4751S missense 0.00002625●●●●●●
2048. 228506705 c.14252G>T p.R4751L missense 0.00002585●●●●●●
2049. 228506714 c.14261C>T p.T4754M missense 0.00002336●●●●●●
2050. 228506725 c.14272A>G p.I4758V missense 0.00002080●●●●●●
2051. 228506729 c.14276G>A p.S4759N missense 0.00002025●●●●●●
2052. 228506749 c.14296G>A p.G4766S missense 0.00004907●●●●●●
2053. 228506749 c.14296G>T p.G4766C missense 0.00001636●●●●●●
2054. 228506752 c.14299C>T p.R4767C missense 0.00006303●●●●●●
2055. 228506752 c.14299C>G p.R4767G missense 0.00001576●●●●●●
2056. 228506753 c.14300G>A p.R4767H missense 0.00001545●●●●●●
2057. 228506756 c.14303C>T p.S4768L missense 0.00475165●●●●●●
2058. 228506761 c.14308C>T p.R4770C missense 0.00159416●●●●●●
2059. 228506762 c.14309G>A p.R4770H missense 0.00002650●●●●●●
2060. 228506762 c.14309G>T p.R4770L missense 0.00001325●●●●●●
2061. 228506768 c.14315C>T p.P4772L missense 0.00024668●●●●●●
2062. 228506784 c.14331G>T p.E4777D missense 0.00002103●●●●●●
2063. 228506786 c.14333T>G p.V4778G missense 0.00001047●●●●●●
2064. 228506789 c.14336C>A p.A4779E missense 0.00001026●●●●●●
2065. 228506816 c.14363C>T p.T4788M missense 0.00004681●●●●●●
2066. 228506833 c.14380C>T p.R4794C missense 0.00008412●●●●●●
2067. 228506834 c.14381G>T p.R4794L missense 0.00001871●●●●●●
2068. 228506834 c.14381G>A p.R4794H missense 0.00002806●●●●●●
2069. 228506836 c.14383A>G p.T4795A missense 0.00003741●●●●●●
2070. 228506845 c.14392G>A p.A4798T missense 0.00000942●●●●●●
2071. 228506854 c.14401T>C p.S4801P missense 0.00004780●●●●●●
2072. 228506855 c.14402C>T p.S4801L missense 0.00000961●●●●●●
2073. 228506857 c.14404C>G p.H4802D missense 0.00000966●●●●●●
2074. 228506881 c.14428C>T p.R4810W missense 0.00027430●●●●●●
2075. 228506882 c.14429G>A p.R4810Q missense 0.00002294●●●●●●
2076. 228506884 c.14431G>A p.A4811T missense 0.00009316●●●●●●
2077. 228506888 c.14435G>T p.G4812V missense 0.00001227●●●●●●
2078. 228506890 c.14437A>G p.T4813A missense 0.00002521●●●●●●
2079. 228506902 c.14449G>A p.V4817I missense 0.00001516●●●●●●
2080. 228506906 c.14453C>T p.T4818I missense 0.00001636●●●●●●
2081. 228506912 c.14459T>C p.L4820P missense 0.00917219●●●●●●
2082. 228506920 c.14467G>A p.A4823T missense 0.00002339●●●●●●
2083. 228509051 c.14509G>T p.A4837S missense 0.00000887●●●●●●
2084. 228509060 c.14518G>A p.A4840T missense 0.00000890●●●●●●
2085. 228509075 c.14533C>A p.P4845T missense 0.00000904●●●●●●
2086. 228509076 c.14534C>T p.P4845L missense 0.00000906●●●●●●
2087. 228509093 c.14551C>A p.P4851T missense 0.00018444●●●●●●
2088. 228509097 c.14555T>C p.L4852P missense 0.00002773●●●●●●
2089. 228509100 c.14558C>T p.A4853V missense 0.00000922●●●●●●
2090. 228509105 c.14563G>A p.V4855M missense 0.00004616●●●●●●
2091. 228509108 c.14566C>T p.R4856C missense 0.00003714●●●●●●
2092. 228509109 c.14567G>A p.R4856H missense 0.00113043●●●●●●
2093. 228509117 c.14575C>A p.L4859M missense 0.00001847●●●●●●
2094. 228509132 c.14590A>G p.T4864A missense 0.00000922●●●●●●
2095. 228509138 c.14596G>C p.D4866H missense 0.00001848●●●●●●
2096. 228509145 c.14603G>C p.G4868A missense 0.00000924●●●●●●
2097. 228509145 c.14603G>A p.G4868D missense 0.00000924●●●●●●
2098. 228509145 c.14603G>T p.G4868V missense 0.00000924●●●●●●
2099. 228509147 c.14605G>C p.D4869H missense 0.00000925●●●●●●
2100. 228509168 c.14626G>A p.A4876T missense 0.00003700●●●●●●
2101. 228509178 c.14636T>C p.I4879T missense 0.00000924●●●●●●
2102. 228509186 c.14644G>A p.A4882T missense 0.00002769●●●●●●
2103. 228509189 c.14647T>C p.F4883L missense 0.00000921●●●●●●
2104. 228509193 c.14651A>C p.K4884T missense 0.00001840●●●●●●
2105. 228509195 c.14653G>T p.G4885C missense 0.00000918●●●●●●
2106. 228509207 c.14665C>T p.R4889W missense 0.00002741●●●●●●
2107. 228509208 c.14666G>A p.R4889Q missense 0.00005467●●●●●●
2108. 228509217 c.14675T>A p.M4892K missense 0.00000900●●●●●●
2109. 228509217 c.14675T>G p.M4892R missense 0.00000900●●●●●●
2110. 228509226 c.14684A>T p.Q4895L missense 0.00000891●●●●●●
2111. 228509264 c.14722G>A p.E4908K missense 0.00004286●●●●●●
2112. 228509273 c.14731G>A p.V4911M missense 0.00000852●●●●●●
2113. 228509277 c.14735G>A p.G4912E missense 0.00002552●●●●●●
2114. 228509279 c.14737G>T p.D4913Y missense 0.00065457●●●●●●
2115. 228509288 c.14746C>G p.R4916G missense 0.00017023●●●●●●
2116. 228509288 c.14746C>T p.R4916W missense 0.00002553●●●●●●
2117. 228509289 c.14747G>A p.R4916Q missense 0.00005100●●●●●●
2118. 228509298 c.14756G>A p.C4919Y missense 0.00000848●●●●●●
2119. 228509303 c.14761G>A p.V4921M missense 0.00002541●●●●●●
2120. 228509310 c.14768G>A p.S4923N missense 0.00003379●●●●●●
2121. 228509321 c.14779G>A p.V4927M missense 0.00037864●●●●●●
2122. 228509325 c.14783G>A p.R4928Q missense 0.00018492●●●●●●
2123. 228509325 c.14783G>T p.R4928L missense 0.00000841●●●●●●
2124. 228509327 c.14785G>A p.A4929T missense 0.00000839●●●●●●
2125. 228509328 c.14786C>T p.A4929V missense 0.00000839●●●●●●
2126. 228509330 c.14788C>A p.R4930S missense 0.00000839●●●●●●
2127. 228509331 c.14789G>A p.R4930H missense 0.00010899●●●●●●
2128. 228509337 c.14795T>C p.L4932P missense 0.00000836●●●●●●
2129. 228509343 c.14801A>C p.D4934A missense 0.00002504●●●●●●
2130. 228509343 c.14801A>G p.D4934G missense 0.00000835●●●●●●
2131. 228509345 c.14803G>A p.G4935S missense 0.00004171●●●●●●
2132. 228509351 c.14809G>A p.E4937K missense 0.00000833●●●●●●
2133. 228509355 c.14813T>C p.L4938P missense 0.00000833●●●●●●
2134. 228509360 c.14818G>A p.D4940N missense 0.00019978●●●●●●
2135. 228509366 c.14824C>T p.R4942W missense 0.00000832●●●●●●
2136. 228509367 c.14825G>A p.R4942Q missense 0.00019963●●●●●●
2137. 228509373 c.14831A>G p.H4944R missense 0.00000831●●●●●●
2138. 228509383 c.14841C>A p.D4947E missense 0.00000831●●●●●●
2139. 228509390 c.14848G>T p.G4950W missense 0.00000831●●●●●●
2140. 228509424 c.14882T>C p.L4961P missense 0.00000831●●●●●●
2141. 228509427 c.14885A>G p.D4962G missense 0.68624604●●●●●●
2142. 228509429 c.14887C>T p.R4963C missense 0.00003329●●●●●●
2143. 228509429 c.14887C>A p.R4963S missense 0.00001665●●●●●●
2144. 228509430 c.14888G>A p.R4963H missense 0.00079904●●●●●●
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2146. 228509444 c.14902T>G p.C4968G missense 0.00000833●●●●●●
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2372. 228525765 c.16921C>T p.L5641F missense 0.00000894●●●●●●
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2380. 228525812 c.16968G>C p.W5656C missense 0.00000900●●●●●●
2381. 228525823 c.16979C>T p.A5660V missense 0.00047072●●●●●●
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2383. 228525832 c.16988A>G p.D5663G missense 0.00000909●●●●●●
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2391. 228526054 c.17065G>A p.E5689K missense 0.00004334●●●●●●
2392. 228526067 c.17078G>T p.R5693M missense 0.00051017●●●●●●
2393. 228526567 c.17098G>C p.E5700Q missense 0.00005478●●●●●●
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2402. 228526672 c.17203G>A p.G5735S missense 0.00006575●●●●●●
2403. 228526693 c.17224C>T p.R5742C missense 0.00015601●●●●●●
2404. 228526694 c.17225G>A p.R5742H missense 0.00007888●●●●●●
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2406. 228526711 c.17242G>A p.G5748S missense 0.00012107●●●●●●
2407. 228526715 c.17246G>T p.R5749L missense 0.00028498●●●●●●
2408. 228526724 c.17255G>T p.S5752I missense 0.00017355●●●●●●
2409. 228527654 c.17267A>T p.Q5756L missense 0.00000830●●●●●●
2410. 228527655 c.17268G>C p.Q5756H missense 0.00000830●●●●●●
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2413. 228527675 c.17288C>T p.T5763M missense 0.00003320●●●●●●
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2415. 228527679 c.17292C>A p.D5764E missense 0.00000830●●●●●●
2416. 228527680 c.17293G>A p.D5765N missense 0.00002490●●●●●●
2417. 228527686 c.17299G>A p.V5767M missense 0.00003320●●●●●●
2418. 228527689 c.17302G>A p.A5768T missense 0.00001660●●●●●●
2419. 228527692 c.17305A>C p.M5769L missense 0.00000830●●●●●●
2420. 228527693 c.17306T>C p.M5769T missense 0.00000830●●●●●●
2421. 228527705 c.17318A>G p.K5773R missense 0.00000830●●●●●●
2422. 228527710 c.17323C>G p.Q5775E missense 0.00000830●●●●●●
2423. 228527714 c.17327C>A p.A5776E missense 0.00000830●●●●●●
2424. 228527716 c.17329G>A p.A5777T missense 0.00000830●●●●●●
2425. 228527720 c.17333T>A p.F5778Y missense 0.00009137●●●●●●
2426. 228527722 c.17335G>A p.E5779K missense 0.00000831●●●●●●
2427. 228527731 c.17344C>G p.L5782V missense 0.00001663●●●●●●
2428. 228527737 c.17350T>G p.F5784V missense 0.00001663●●●●●●
2429. 228527743 c.17356G>A p.V5786M missense 0.00000833●●●●●●
2430. 228527749 c.17362C>T p.R5788C missense 0.00305112●●●●●●
2431. 228527750 c.17363G>A p.R5788H missense 0.00005836●●●●●●
2432. 228527752 c.17365G>T p.V5789L missense 0.00000834●●●●●●
2433. 228527752 c.17365G>A p.V5789M missense 0.00000834●●●●●●
2434. 228527758 c.17371G>C p.A5791P missense 0.00044378●●●●●●
2435. 228527762 c.17375A>T p.E5792V missense 0.00000840●●●●●●
2436. 228527763 c.17376G>C p.E5792D missense 0.00009289●●●●●●
2437. 228527765 c.17378C>T p.S5793L missense 0.00010136●●●●●●
2438. 228527770 c.17383G>C p.V5795L missense 0.00000851●●●●●●
2439. 228527771 c.17384T>C p.V5795A missense 0.00005129●●●●●●
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2441. 228527773 c.17386G>A p.V5796I missense 0.00001720●●●●●●
2442. 228527777 c.17390G>A p.S5797N missense 0.00012157●●●●●●
2443. 228527779 c.17392A>C p.T5798P missense 0.00009645●●●●●●
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2445. 228527780 c.17393C>T p.T5798M missense 0.00000877●●●●●●
2446. 228527788 c.17401C>A p.Q5801K missense 0.00000905●●●●●●
2447. 228528213 c.17422G>A p.A5808T missense 0.00017354●●●●●●
2448. 228528214 c.17423C>T p.A5808V missense 0.00034420●●●●●●
2449. 228528244 c.17453C>T p.S5818F missense 0.00003192●●●●●●
2450. 228528253 c.17462C>T p.P5821L missense 0.00008667●●●●●●
2451. 228528268 c.17477A>C p.Q5826P missense 0.00012246●●●●●●
2452. 228528294 c.17503C>T p.R5835W missense 0.00009274●●●●●●
2453. 228528295 c.17504G>A p.R5835Q missense 0.00009200●●●●●●
2454. 228528297 c.17506G>A p.V5836M missense 0.00011408●●●●●●
2455. 228528298 c.17507T>C p.V5836A missense 0.00425318●●●●●●
2456. 228528303 c.17512C>T p.R5838C missense 0.00004551●●●●●●
2457. 228528434 c.17542C>T p.R5848C missense 0.00015029●●●●●●
2458. 228528443 c.17551G>A p.A5851T missense 0.00000954●●●●●●
2459. 228528446 c.17554C>T p.R5852W missense 0.00001924●●●●●●
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2462. 228528464 c.17572G>A p.A5858T missense 0.00002077●●●●●●
2463. 228528465 c.17573C>A p.A5858E missense 0.00003134●●●●●●
2464. 228528465 c.17573C>T p.A5858V missense 0.00002089●●●●●●
2465. 228528488 c.17596G>A p.V5866M missense 0.00005788●●●●●●
2466. 228528495 c.17603C>A p.S5868Y missense 0.00002375●●●●●●
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2468. 228528512 c.17620G>A p.A5874T missense 0.00004914●●●●●●
2469. 228528530 c.17638G>A p.V5880M missense 0.00041618●●●●●●
2470. 228528549 c.17657A>G p.Y5886C missense 0.00118275●●●●●●
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2472. 228528563 c.17671C>G p.Q5891E missense 0.54681826●●●●●●
2473. 228528567 c.17675C>T p.A5892V missense 0.00001720●●●●●●
2474. 228528575 c.17683G>A p.E5895K missense 0.00015004●●●●●●
2475. 228528584 c.17692C>T p.R5898C missense 0.00006078●●●●●●
2476. 228528799 c.17701C>T p.H5901Y missense 0.00002086●●●●●●
2477. 228528808 c.17710G>A p.V5904M missense 0.00001964●●●●●●
2478. 228528813 c.17715G>T p.W5905C missense 0.00000957●●●●●●
2479. 228528824 c.17726C>T p.P5909L missense 0.00004605●●●●●●
2480. 228528830 c.17732C>T p.A5911V missense 0.00005411●●●●●●
2481. 228528833 c.17735G>A p.R5912H missense 0.00007178●●●●●●
2482. 228528836 c.17738T>A p.M5913K missense 0.00000888●●●●●●
2483. 228528850 c.17752C>G p.H5918D missense 0.00002620●●●●●●
2484. 228528859 c.17761C>A p.H5921N missense 0.00000865●●●●●●
2485. 228528862 c.17764G>T p.V5922L missense 0.00000862●●●●●●
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2487. 228528866 c.17768T>C p.F5923S missense 0.00000860●●●●●●
2488. 228528868 c.17770C>T p.L5924F missense 0.00001717●●●●●●
2489. 228528871 c.17773T>C p.F5925L missense 0.00000857●●●●●●
2490. 228528872 c.17774T>C p.F5925S missense 0.00000857●●●●●●
2491. 228528874 c.17776C>T p.R5926C missense 0.00004283●●●●●●
2492. 228528875 c.17777G>A p.R5926H missense 0.00005138●●●●●●
2493. 228528875 c.17777G>T p.R5926L missense 0.00003425●●●●●●
2494. 228528877 c.17779A>C p.N5927H missense 0.00000854●●●●●●
2495. 228528883 c.17785C>G p.L5929V missense 0.00002556●●●●●●
2496. 228528901 c.17803C>T p.R5935W missense 0.00003394●●●●●●
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2499. 228528905 c.17807G>A p.R5936Q missense 0.00003390●●●●●●
2500. 228528909 c.17811C>G p.D5937E missense 0.00001694●●●●●●
2501. 228528910 c.17812T>G p.S5938A missense 0.00000847●●●●●●
2502. 228528913 c.17815C>T p.R5939C missense 0.00002540●●●●●●
2503. 228528914 c.17816G>T p.R5939L missense 0.00000847●●●●●●
2504. 228528925 c.17827G>A p.V5943I missense 0.00005924●●●●●●
2505. 228528932 c.17834A>T p.Y5945F missense 0.00000847●●●●●●
2506. 228528934 c.17836G>A p.V5946M missense 0.00009316●●●●●●
2507. 228528939 c.17841C>G p.F5947L missense 0.00000847●●●●●●
2508. 228528941 c.17843G>A p.R5948Q missense 0.00002544●●●●●●
2509. 228528950 c.17852T>C p.M5951T missense 0.00000849●●●●●●
2510. 228529147 c.17866A>G p.I5956V missense 0.00000894●●●●●●
2511. 228529147 c.17866A>T p.I5956F missense 0.00000894●●●●●●
2512. 228529154 c.17873T>C p.L5958P missense 0.00001765●●●●●●
2513. 228529157 c.17876A>T p.N5959I missense 0.00001757●●●●●●
2514. 228529159 c.17878G>A p.D5960N missense 0.00004381●●●●●●
2515. 228529172 c.17891G>A p.G5964E missense 0.00001729●●●●●●
2516. 228529181 c.17900G>T p.R5967L missense 0.00000860●●●●●●
2517. 228529181 c.17900G>A p.R5967H missense 0.00002581●●●●●●
2518. 228529183 c.17902G>A p.A5968T missense 0.00006869●●●●●●
2519. 228529189 c.17908G>A p.E5970K missense 0.00001711●●●●●●
2520. 228529199 c.17918A>G p.Q5973R missense 0.00000861●●●●●●
2521. 228529210 c.17929G>A p.D5977N missense 0.00000861●●●●●●
2522. 228529211 c.17930A>T p.D5977V missense 0.00000861●●●●●●
2523. 228529214 c.17933C>T p.S5978L missense 0.00006024●●●●●●
2524. 228529219 c.17938C>T p.R5980C missense 0.00003433●●●●●●
2525. 228529220 c.17939G>T p.R5980L missense 0.00003433●●●●●●
2526. 228529220 c.17939G>A p.R5980H missense 0.00004291●●●●●●
2527. 228529224 c.17943G>C p.K5981N missense 0.00000859●●●●●●
2528. 228529240 c.17959C>T p.R5987W missense 0.00001703●●●●●●
2529. 228529241 c.17960G>A p.R5987Q missense 0.00005108●●●●●●
2530. 228529247 c.17966C>A p.A5989D missense 0.00010188●●●●●●
2531. 228529266 c.17985G>C p.W5995C missense 0.00000850●●●●●●
2532. 228529292 c.18011A>T p.Q6004L missense 0.00000860●●●●●●
2533. 228529294 c.18013C>T p.R6005C missense 0.00002584●●●●●●
2534. 228529295 c.18014G>C p.R6005P missense 0.00000863●●●●●●
2535. 228529295 c.18014G>A p.R6005H missense 0.00006902●●●●●●
2536. 228529309 c.18028G>A p.V6010M missense 0.00000874●●●●●●
2537. 228529312 c.18031T>C p.W6011R missense 0.00000878●●●●●●
2538. 228529315 c.18034C>T p.R6012W missense 0.00001763●●●●●●
2539. 228529820 c.18035G>A p.R6012Q missense 0.00002653●●●●●●
2540. 228529822 c.18037C>A p.P6013T missense 0.00005126●●●●●●
2541. 228529842 c.18057G>T p.E6019D missense 0.00001910●●●●●●
2542. 228529849 c.18064G>A p.D6022N missense 0.00001800●●●●●●
2543. 228529861 c.18076G>A p.E6026K missense 0.00005117●●●●●●
2544. 228529863 c.18078G>T p.E6026D missense 0.00001682●●●●●●
2545. 228529868 c.18083G>A p.G6028D missense 0.00001632●●●●●●
2546. 228529870 c.18085G>A p.E6029K missense 0.00001631●●●●●●
2547. 228529880 c.18095A>C p.K6032T missense 0.00001655●●●●●●
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2549. 228529891 c.18106C>T p.R6036C missense 0.00003515●●●●●●
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2551. 228529894 c.18109G>A p.V6037M missense 0.00005344●●●●●●
2552. 228529898 c.18113C>T p.T6038M missense 0.00005515●●●●●●
2553. 228529901 c.18116G>A p.G6039D missense 0.00001896●●●●●●
2554. 228529912 c.18127C>T p.P6043S missense 0.00007711●●●●●●
2555. 228537608 c.18166G>A p.V6056M missense 0.00004582●●●●●●
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2560. 228537638 c.18196C>T p.P6066S missense 0.00004346●●●●●●
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2562. 228537645 c.18203G>A p.G6068D missense 0.00004357●●●●●●
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2574. 228538550 c.18325C>T p.R6109W missense 0.00010019●●●●●●
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2580. 228538568 c.18343C>T p.R6115W missense 0.00004185●●●●●●
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2582. 228538577 c.18352C>T p.P6118S missense 0.00000840●●●●●●
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2589. 228538635 c.18410C>T p.P6137L missense 0.00068050●●●●●●
2590. 228538637 c.18412C>A p.Q6138K missense 0.00000898●●●●●●
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2594. 228539084 c.18482G>T p.R6161L missense 0.00003935●●●●●●
2595. 228539110 c.18508C>T p.R6170W missense 0.00003824●●●●●●
2596. 228539111 c.18509G>A p.R6170Q missense 0.00007644●●●●●●
2597. 228540656 c.18554T>C p.V6185A missense 0.00007066●●●●●●
2598. 228540661 c.18559C>T p.R6187W missense 0.00021468●●●●●●
2599. 228540673 c.18571G>A p.A6191T missense 0.00006238●●●●●●
2600. 228540674 c.18572C>T p.A6191V missense 0.00006154●●●●●●
2601. 228540677 c.18575G>A p.R6192Q missense 0.00011811●●●●●●
2602. 228540684 c.18582T>A p.S6194R missense 0.00005506●●●●●●
2603. 228540686 c.18584C>A p.A6195E missense 0.00005453●●●●●●
2604. 228540686 c.18584C>T p.A6195V missense 0.00005453●●●●●●
2605. 228540694 c.18592C>T p.R6198C missense 0.00010172●●●●●●
2606. 228540697 c.18595A>C p.I6199L missense 0.00004932●●●●●●
2607. 228540713 c.18611T>C p.L6204P missense 0.00004562●●●●●●
2608. 228540742 c.18640C>A p.Q6214K missense 0.00004494●●●●●●
2609. 228540757 c.18655G>A p.V6219M missense 0.00004898●●●●●●
2610. 228543869 c.18679A>G p.K6227E missense 0.00000828●●●●●●
2611. 228543870 c.18680A>C p.K6227T missense 0.00000828●●●●●●
2612. 228543885 c.18695C>G p.T6232S missense 0.00000828●●●●●●
2613. 228543887 c.18697G>A p.V6233I missense 0.00006624●●●●●●
2614. 228547302 c.18709G>C p.E6237Q missense 0.00002761●●●●●●
2615. 228547305 c.18712A>G p.T6238A missense 0.00002653●●●●●●
2616. 228547324 c.18731A>G p.K6244R missense 0.00002211●●●●●●
2617. 228547332 c.18739C>T p.R6247C missense 0.00004245●●●●●●
2618. 228547339 c.18746A>G p.Q6249R missense 0.00002020●●●●●●
2619. 228547345 c.18752G>T p.R6251L missense 0.00009912●●●●●●
2620. 228547345 c.18752G>C p.R6251P missense 0.00001982●●●●●●
2621. 228547369 c.18776G>A p.R6259H missense 0.00004012●●●●●●
2622. 228547369 c.18776G>T p.R6259L missense 0.00002006●●●●●●
2623. 228547380 c.18787C>T p.R6263C missense 0.00006100●●●●●●
2624. 228547381 c.18788G>A p.R6263H missense 0.00002035●●●●●●
2625. 228547396 c.18803C>T p.P6268L missense 0.00006195●●●●●●
2626. 228547407 c.18814G>A p.G6272S missense 0.00002102●●●●●●
2627. 228547417 c.18824C>A p.A6275D missense 0.00004250●●●●●●
2628. 228547419 c.18826C>T p.P6276S missense 0.00002111●●●●●●
2629. 228547450 c.18857A>G p.Q6286R missense 0.00001820●●●●●●
2630. 228547455 c.18862C>T p.R6288C missense 0.00010671●●●●●●
2631. 228547456 c.18863G>A p.R6288H missense 0.00008865●●●●●●
2632. 228547476 c.18883G>A p.G6295S missense 0.00003153●●●●●●
2633. 228547477 c.18884G>A p.G6295D missense 0.00001576●●●●●●
2634. 228547488 c.18895G>A p.V6299M missense 0.00009245●●●●●●
2635. 228547494 c.18901C>G p.P6301A missense 0.00068875●●●●●●
2636. 228547497 c.18904A>T p.T6302S missense 0.00001524●●●●●●
2637. 228547510 c.18917C>T p.T6306M missense 0.00001554●●●●●●
2638. 228547512 c.18919G>C p.E6307Q missense 0.00010900●●●●●●
2639. 228547518 c.18925G>A p.E6309K missense 0.00004685●●●●●●
2640. 228547530 c.18937C>G p.P6313A missense 0.00001587●●●●●●
2641. 228547530 c.18937C>T p.P6313S missense 0.00001587●●●●●●
2642. 228547531 c.18938C>G p.P6313R missense 0.00001584●●●●●●
2643. 228547542 c.18949G>A p.G6317R missense 0.00008017●●●●●●
2644. 228547549 c.18956C>T p.S6319L missense 0.00017474●●●●●●
2645. 228547555 c.18962C>T p.P6321L missense 0.00001583●●●●●●
2646. 228547564 c.18971A>C p.K6324T missense 0.00009485●●●●●●
2647. 228547575 c.18982G>A p.V6328M missense 0.00003168●●●●●●
2648. 228547588 c.18995T>C p.I6332T missense 0.00027860●●●●●●
2649. 228547596 c.19003C>T p.R6335W missense 0.00003406●●●●●●
2650. 228547597 c.19004G>A p.R6335Q missense 0.00022394●●●●●●
2651. 228547612 c.19019G>A p.G6340D missense 0.00001893●●●●●●
2652. 228547623 c.19030G>A p.V6344M missense 0.00004144●●●●●●
2653. 228547640 c.19047G>C p.E6349D missense 0.00002376●●●●●●
2654. 228547657 c.19064C>T p.S6355L missense 0.00011353●●●●●●
2655. 228547665 c.19072C>A p.L6358I missense 0.00002943●●●●●●
2656. 228547680 c.19087G>C p.G6363R missense 0.00012749●●●●●●
2657. 228547680 c.19087G>A p.G6363S missense 0.00015936●●●●●●
2658. 228547684 c.19091C>T p.A6364V missense 0.00003296●●●●●●
2659. 228547689 c.19096C>A p.P6366T missense 0.00013223●●●●●●
2660. 228547692 c.19099G>A p.G6367R missense 0.00003340●●●●●●
2661. 228547707 c.19114T>C p.S6372P missense 0.00003292●●●●●●
2662. 228547761 c.19168G>A p.A6390T missense 0.00002475●●●●●●
2663. 228547770 c.19177G>A p.G6393S missense 0.00013524●●●●●●
2664. 228547773 c.19180G>A p.V6394I missense 0.00012988●●●●●●
2665. 228547794 c.19201C>T p.R6401C missense 0.00007048●●●●●●
2666. 228547797 c.19204G>A p.V6402M missense 0.00006529●●●●●●
2667. 228547803 c.19210G>A p.A6404T missense 0.00001503●●●●●●
2668. 228547804 c.19211C>T p.A6404V missense 0.00001490●●●●●●
2669. 228547816 c.19223T>C p.V6408A missense 0.00007822●●●●●●
2670. 228547827 c.19234G>C p.A6412P missense 0.01063683●●●●●●
2671. 228547831 c.19238C>G p.S6413C missense 0.00001117●●●●●●
2672. 228547851 c.19258G>C p.E6420Q missense 0.00000967●●●●●●
2673. 228547857 c.19264G>C p.G6422R missense 0.00002816●●●●●●
2674. 228547864 c.19271T>G p.M6424R missense 0.00001825●●●●●●
2675. 228547865 c.19272G>A p.M6424I missense 0.00000911●●●●●●
2676. 228547873 c.19280C>T p.A6427V missense 0.00010674●●●●●●
2677. 228547882 c.19289A>G p.E6430G missense 0.00000865●●●●●●
2678. 228547884 c.19291G>A p.E6431K missense 0.00000862●●●●●●
2679. 228547886 c.19293G>C p.E6431D missense 0.00006013●●●●●●
2680. 228547888 c.19295G>T p.G6432V missense 0.00000857●●●●●●
2681. 228547888 c.19295G>A p.G6432E missense 0.00002571●●●●●●
2682. 228547893 c.19300G>A p.D6434N missense 0.00000851●●●●●●
2683. 228547896 c.19303G>A p.G6435R missense 0.00001697●●●●●●
2684. 228547902 c.19309G>A p.A6437T missense 0.00002516●●●●●●
2685. 228547902 c.19309G>C p.A6437P missense 0.00000839●●●●●●
2686. 228547912 c.19319C>T p.T6440M missense 0.00012565●●●●●●
2687. 228547937 c.19344C>A p.S6448R missense 0.00000837●●●●●●
2688. 228547948 c.19355G>A p.R6452H missense 0.00000837●●●●●●
2689. 228547948 c.19355G>T p.R6452L missense 0.00001674●●●●●●
2690. 228547953 c.19360C>T p.P6454S missense 0.00004184●●●●●●
2691. 228547961 c.19368C>G p.I6456M missense 0.00003348●●●●●●
2692. 228547966 c.19373C>T p.T6458M missense 0.00002512●●●●●●
2693. 228547968 c.19375C>T p.H6459Y missense 0.00001674●●●●●●
2694. 228547977 c.19384C>T p.R6462C missense 0.00002513●●●●●●
2695. 228547978 c.19385G>T p.R6462L missense 0.00000838●●●●●●
2696. 228547978 c.19385G>A p.R6462H missense 0.00004189●●●●●●
2697. 228547987 c.19394C>T p.T6465I missense 0.00000838●●●●●●
2698. 228548001 c.19408G>A p.E6470K missense 0.00003358●●●●●●
2699. 228548025 c.19432G>A p.E6478K missense 0.00006741●●●●●●
2700. 228548029 c.19436C>A p.T6479N missense 0.00000843●●●●●●
2701. 228548038 c.19445G>A p.C6482Y missense 0.00001689●●●●●●
2702. 228548044 c.19451G>A p.G6484D missense 0.00001691●●●●●●
2703. 228548046 c.19453C>T p.P6485S missense 0.00000846●●●●●●
2704. 228548058 c.19465G>A p.A6489T missense 0.00009326●●●●●●
2705. 228548064 c.19471G>A p.D6491N missense 0.00000849●●●●●●
2706. 228548065 c.19472A>G p.D6491G missense 0.00000849●●●●●●
2707. 228548066 c.19473T>A p.D6491E missense 0.00001699●●●●●●
2708. 228548074 c.19481C>G p.P6494R missense 0.00001700●●●●●●
2709. 228548079 c.19486G>A p.E6496K missense 0.00003404●●●●●●
2710. 228548086 c.19493C>T p.S6498L missense 0.00001704●●●●●●
2711. 228548088 c.19495G>C p.V6499L missense 0.00000852●●●●●●
2712. 228548098 c.19505G>T p.R6502I missense 0.00000855●●●●●●
2713. 228548101 c.19508A>C p.E6503A missense 0.00000856●●●●●●
2714. 228548106 c.19513G>A p.G6505R missense 0.00015436●●●●●●
2715. 228548106 c.19513G>C p.G6505R missense 0.00000858●●●●●●
2716. 228548107 c.19514G>A p.G6505E missense 0.00001719●●●●●●
2717. 228548112 c.19519C>T p.P6507S missense 0.00242877●●●●●●
2718. 228548116 c.19523C>A p.T6508K missense 0.01091899●●●●●●
2719. 228548116 c.19523C>T p.T6508M missense 0.00006052●●●●●●
2720. 228548137 c.19544T>C p.L6515P missense 0.00001769●●●●●●
2721. 228548139 c.19546A>C p.S6516R missense 0.00000888●●●●●●
2722. 228548142 c.19549G>A p.V6517M missense 0.00004457●●●●●●
2723. 228548142 c.19549G>C p.V6517L missense 0.00000891●●●●●●
2724. 228548143 c.19550T>G p.V6517G missense 0.00000892●●●●●●
2725. 228548146 c.19553G>A p.G6518E missense 0.00000900●●●●●●
2726. 228548148 c.19555C>T p.H6519Y missense 0.00000900●●●●●●
2727. 228548150 c.19557T>A p.H6519Q missense 0.00001807●●●●●●
2728. 228548164 c.19571G>A p.R6524Q missense 0.00000939●●●●●●
2729. 228548175 c.19582G>A p.G6528S missense 0.00002897●●●●●●
2730. 228548175 c.19582G>T p.G6528C missense 0.00000966●●●●●●
2731. 228548193 c.19600C>T p.P6534S missense 0.00001954●●●●●●
2732. 228548194 c.19601C>T p.P6534L missense 0.00001948●●●●●●
2733. 228548197 c.19604G>A p.R6535H missense 0.13112623●●●●●●
2734. 228548202 c.19609G>T p.A6537S missense 0.00000982●●●●●●
2735. 228548209 c.19616C>T p.P6539L missense 0.00000987●●●●●●
2736. 228548212 c.19619C>T p.P6540L missense 0.00006941●●●●●●
2737. 228548217 c.19624C>T p.P6542S missense 0.00000987●●●●●●
2738. 228548218 c.19625C>T p.P6542L missense 0.00000988●●●●●●
2739. 228548220 c.19627C>A p.Q6543K missense 0.00000988●●●●●●
2740. 228548223 c.19630G>T p.V6544F missense 0.00003941●●●●●●
2741. 228548226 c.19633C>T p.R6545C missense 0.00005923●●●●●●
2742. 228548239 c.19646G>A p.G6549D missense 0.00001951●●●●●●
2743. 228548242 c.19649C>T p.T6550I missense 0.00000972●●●●●●
2744. 228548255 c.19662G>C p.L6554F missense 0.00072709●●●●●●
2745. 228548256 c.19663C>T p.R6555W missense 0.00033665●●●●●●
2746. 228548257 c.19664G>C p.R6555P missense 0.00001912●●●●●●
2747. 228548257 c.19664G>A p.R6555Q missense 0.00002868●●●●●●
2748. 228548259 c.19666G>A p.E6556K missense 0.00000950●●●●●●
2749. 228548266 c.19673C>T p.P6558L missense 0.00016132●●●●●●
2750. 228548271 c.19678C>T p.R6560W missense 0.00002819●●●●●●
2751. 228548271 c.19678C>G p.R6560G missense 0.00000940●●●●●●
2752. 228548272 c.19679G>A p.R6560Q missense 0.00005645●●●●●●
2753. 228548290 c.19697C>T p.P6566L missense 0.00388083●●●●●●
2754. 228548292 c.19699T>C p.W6567R missense 0.00002764●●●●●●
2755. 228548296 c.19703C>T p.T6568M missense 0.00018459●●●●●●
2756. 228548301 c.19708T>G p.S6570A missense 0.00000919●●●●●●
2757. 228548302 c.19709C>T p.S6570F missense 0.00001842●●●●●●
2758. 228548308 c.19715G>A p.C6572Y missense 0.00000922●●●●●●
2759. 228548313 c.19720C>T p.R6574C missense 0.00000925●●●●●●
2760. 228548314 c.19721G>A p.R6574H missense 0.00001850●●●●●●
2761. 228548319 c.19726C>T p.R6576W missense 0.00002777●●●●●●
2762. 228548320 c.19727G>A p.R6576Q missense 0.00001849●●●●●●
2763. 228548322 c.19729C>T p.R6577C missense 0.00000924●●●●●●
2764. 228548323 c.19730G>A p.R6577H missense 0.00000923●●●●●●
2765. 228548329 c.19736C>T p.A6579V missense 0.00007399●●●●●●
2766. 228548337 c.19744G>A p.G6582S missense 0.00000925●●●●●●
2767. 228548347 c.19754G>C p.S6585T missense 0.00003713●●●●●●
2768. 228548355 c.19762A>G p.T6588A missense 0.00018599●●●●●●
2769. 228548376 c.19783G>A p.V6595I missense 0.00003751●●●●●●
2770. 228548381 c.19788C>G p.N6596K missense 0.00000939●●●●●●
2771. 228548382 c.19789T>A p.F6597I missense 0.00006579●●●●●●
2772. 228548384 c.19791C>G p.F6597L missense 0.00001881●●●●●●
2773. 228548385 c.19792G>A p.G6598R missense 0.00000944●●●●●●
2774. 228548392 c.19799T>G p.V6600G missense 0.00001890●●●●●●
2775. 228548394 c.19801G>T p.G6601W missense 0.00000946●●●●●●
2776. 228548394 c.19801G>A p.G6601R missense 0.00000946●●●●●●
2777. 228548401 c.19808C>T p.T6603M missense 0.00001900●●●●●●
2778. 228548421 c.19828C>T p.P6610S missense 0.00000963●●●●●●
2779. 228548432 c.19839T>G p.D6613E missense 0.00001952●●●●●●
2780. 228548433 c.19840G>T p.G6614W missense 0.00005870●●●●●●
2781. 228548443 c.19850C>T p.A6617V missense 0.00004012●●●●●●
2782. 228548449 c.19856A>G p.Q6619R missense 0.00001020●●●●●●

* This highlights the relative frequency of the variant in the ExAC populations - Non-Finnish European, African, East Asian, South Asian, American and Finnish. Higher frequencies are denoted by darker shades of green, variants absent in a population are coloured light gray.

✝ Genomic coordinates refer to the GRCh37 release of the human genome.