TRIM55 missense variants in ExAC

TRIM55 gene summary
TRIM55 variants in

The table below lists the TRIM55 missense variants found in the ExAC population database. Click on each variant for more details, including presence in the 1000 Genomes and Exome Sequencing Project databases, a breakdown by ethnic class and the variant's role in inherited cardiac disease. Use the form below to customise the variant selection. The table can be sorted by variant location, variant type or ExAC frequency.




No. Genomic coord.✝ Variant (CDS)▼ Variant (Protein) Variant Type▼ ExAC frequency▼Populations*
1. 67064654 c.1028A>G p.K343R missense 0.14103252●●●●●●
2. 67066396 c.1351C>T p.R451W missense 0.00191994●●●●●●
3. 67047301 c.418G>A p.E140K missense 0.00180381●●●●●●
4. 67047241 c.358G>T p.D120Y missense 0.00065108●●●●●●
5. 67066435 c.1390G>A p.E464K missense 0.00050261●●●●●●
6. 67066394 c.1349C>T p.T450I missense 0.00046968●●●●●●
7. 67061980 c.704G>A p.R235Q missense 0.00040366●●●●●●
8. 67086762 c.1581T>G p.S527R missense 0.00026585●●●●●●
9. 67066511 c.1466C>T p.A489V missense 0.00026424●●●●●●
10. 67061983 c.707C>T p.T236I missense 0.00025538●●●●●●
11. 67047352 c.469C>A p.Q157K missense 0.00024710●●●●●●
12. 67066367 c.1322T>G p.F441C missense 0.00019783●●●●●●
13. 67064719 c.1093G>A p.E365K missense 0.00019018●●●●●●
14. 67040600 c.230G>A p.R77H missense 0.00016485●●●●●●
15. 67040549 c.179C>T p.P60L missense 0.00014272●●●●●●
16. 67062681 c.965G>A p.R322H missense 0.00014008●●●●●●
17. 67047274 c.391C>T p.R131C missense 0.00014003●●●●●●
18. 67064800 c.1174C>A p.P392T missense 0.00013234●●●●●●
19. 67066544 c.1499C>T p.T500I missense 0.00011568●●●●●●
20. 67062012 c.736G>T p.A246S missense 0.00010709●●●●●●
21. 67061923 c.647A>G p.D216G missense 0.00009915●●●●●●
22. 67064788 c.1162C>G p.P388A missense 0.00007439●●●●●●
23. 67086718 c.1537G>T p.A513S missense 0.00007415●●●●●●
24. 67062015 c.739C>G p.L247V missense 0.00007414●●●●●●
25. 67047354 c.471G>C p.Q157H missense 0.00007413●●●●●●
26. 67064632 c.1006G>C p.E336Q missense 0.00006922●●●●●●
27. 67064686 c.1060G>A p.V354I missense 0.00005927●●●●●●
28. 67066516 c.1471G>A p.E491K missense 0.00005778●●●●●●
29. 67040626 c.256G>A p.V86I missense 0.00005767●●●●●●
30. 67062624 c.908G>C p.G303A missense 0.00005767●●●●●●
31. 67086721 c.1540C>T p.P514S missense 0.00005767●●●●●●
32. 67047376 c.493T>C p.F165L missense 0.00005766●●●●●●
33. 67064641 c.1015G>A p.G339R missense 0.00005607●●●●●●
34. 67062082 c.806T>G p.M269R missense 0.00004945●●●●●●
35. 67086731 c.1550A>G p.Q517R missense 0.00004944●●●●●●
36. 67062635 c.919A>G p.M307V missense 0.00004943●●●●●●
37. 67062692 c.976T>G p.F326V missense 0.00004121●●●●●●
38. 67062593 c.877A>G p.K293E missense 0.00004120●●●●●●
39. 67086719 c.1538C>T p.A513V missense 0.00004120●●●●●●
40. 67064644 c.1018G>A p.E340K missense 0.00003837●●●●●●
41. 67066355 c.1310C>T p.A437V missense 0.00003298●●●●●●
42. 67086793 c.1612T>G p.F538V missense 0.00003298●●●●●●
43. 67062637 c.921G>A p.M307I missense 0.00003296●●●●●●
44. 67062624 c.908G>A p.G303D missense 0.00003295●●●●●●
45. 67047290 c.407G>C p.C136S missense 0.00003295●●●●●●
46. 67039576 c.73A>G p.I25V missense 0.00003295●●●●●●
47. 67064678 c.1052G>T p.G351V missense 0.00002611●●●●●●
48. 67064825 c.1199C>T p.P400L missense 0.00002486●●●●●●
49. 67049376 c.554G>A p.R185Q missense 0.00002479●●●●●●
50. 67064752 c.1126G>T p.A376S missense 0.00002479●●●●●●
51. 67066518 c.1473G>T p.E491D missense 0.00002476●●●●●●
52. 67062582 c.866C>T p.S289L missense 0.00002474●●●●●●
53. 67062087 c.811G>A p.E271K missense 0.00002473●●●●●●
54. 67086752 c.1571C>T p.A524V missense 0.00002472●●●●●●
55. 67062636 c.920T>G p.M307R missense 0.00002472●●●●●●
56. 67086717 c.1536G>C p.E512D missense 0.00002472●●●●●●
57. 67066401 c.1356A>T p.K452N missense 0.00002472●●●●●●
58. 67062596 c.880G>A p.A294T missense 0.00002472●●●●●●
59. 67047371 c.488A>G p.H163R missense 0.00002471●●●●●●
60. 67039604 c.101C>T p.T34M missense 0.00002471●●●●●●
61. 67062009 c.733C>T p.R245C missense 0.00002471●●●●●●
62. 67064666 c.1040G>A p.G347E missense 0.00001861●●●●●●
63. 67064851 c.1225C>T p.P409S missense 0.00001668●●●●●●
64. 67066561 c.1516A>G p.T506A missense 0.00001660●●●●●●
65. 67061906 c.630G>C p.E210D missense 0.00001660●●●●●●
66. 67049346 c.524G>C p.G175A missense 0.00001657●●●●●●
67. 67066306 c.1261G>A p.E421K missense 0.00001654●●●●●●
68. 67066307 c.1262A>G p.E421G missense 0.00001654●●●●●●
69. 67064798 c.1172T>A p.L391H missense 0.00001654●●●●●●
70. 67049360 c.538G>A p.V180M missense 0.00001653●●●●●●
71. 67066507 c.1462G>A p.A488T missense 0.00001652●●●●●●
72. 67040582 c.212C>G p.A71G missense 0.00001652●●●●●●
73. 67049363 c.541G>T p.G181C missense 0.00001652●●●●●●
74. 67049371 c.549C>A p.N183K missense 0.00001652●●●●●●
75. 67066508 c.1463C>T p.A488V missense 0.00001651●●●●●●
76. 67066331 c.1286C>T p.P429L missense 0.00001651●●●●●●
77. 67040594 c.224G>A p.R75Q missense 0.00001649●●●●●●
78. 67086790 c.1609A>G p.I537V missense 0.00001649●●●●●●
79. 67061950 c.674G>A p.R225K missense 0.00001649●●●●●●
80. 67066471 c.1426G>A p.D476N missense 0.00001648●●●●●●
81. 67062603 c.887A>T p.Q296L missense 0.00001648●●●●●●
82. 67086739 c.1558G>T p.A520S missense 0.00001648●●●●●●
83. 67040608 c.238T>C p.S80P missense 0.00001648●●●●●●
84. 67062689 c.973G>A p.D325N missense 0.00001648●●●●●●
85. 67086749 c.1568C>T p.P523L missense 0.00001648●●●●●●
86. 67047251 c.368T>C p.M123T missense 0.00001648●●●●●●
87. 67047343 c.460A>G p.K154E missense 0.00001647●●●●●●
88. 67062006 c.730G>A p.V244I missense 0.00001647●●●●●●
89. 67064639 c.1013G>A p.G338D missense 0.00001506●●●●●●
90. 67061880 c.604G>C p.E202Q missense 0.00000853●●●●●●
91. 67066495 c.1450G>C p.V484L missense 0.00000852●●●●●●
92. 67040539 c.169G>A p.A57T missense 0.00000851●●●●●●
93. 67049417 c.595A>T p.T199S missense 0.00000839●●●●●●
94. 67049411 c.589T>A p.C197S missense 0.00000835●●●●●●
95. 67066282 c.1237G>A p.G413R missense 0.00000834●●●●●●
96. 67040557 c.187C>A p.P63T missense 0.00000833●●●●●●
97. 67061899 c.623A>G p.K208R missense 0.00000833●●●●●●
98. 67049334 c.512A>G p.E171G missense 0.00000833●●●●●●
99. 67064843 c.1217C>T p.A406V missense 0.00000832●●●●●●
100. 67061901 c.625C>A p.Q209K missense 0.00000832●●●●●●
101. 67049402 c.580G>A p.E194K missense 0.00000831●●●●●●
102. 67040561 c.191C>T p.T64I missense 0.00000831●●●●●●
103. 67064840 c.1214C>T p.A405V missense 0.00000831●●●●●●
104. 67064831 c.1205T>A p.L402Q missense 0.00000830●●●●●●
105. 67049400 c.578T>A p.L193Q missense 0.00000830●●●●●●
106. 67064836 c.1210C>T p.P404S missense 0.00000830●●●●●●
107. 67066561 c.1516A>T p.T506S missense 0.00000830●●●●●●
108. 67062462 c.848C>G p.T283S missense 0.00000830●●●●●●
109. 67040563 c.193A>G p.R65G missense 0.00000830●●●●●●
110. 67061910 c.634T>C p.C212R missense 0.00000829●●●●●●
111. 67062474 c.860A>T p.K287I missense 0.00000829●●●●●●
112. 67064822 c.1196C>T p.P399L missense 0.00000829●●●●●●
113. 67064810 c.1184C>T p.S395F missense 0.00000828●●●●●●
114. 67064710 c.1084G>A p.V362I missense 0.00000828●●●●●●
115. 67049351 c.529G>A p.A177T missense 0.00000828●●●●●●
116. 67066300 c.1255G>C p.G419R missense 0.00000828●●●●●●
117. 67064819 c.1193C>A p.P398Q missense 0.00000828●●●●●●
118. 67064809 c.1183T>C p.S395P missense 0.00000828●●●●●●
119. 67040575 c.205A>G p.T69A missense 0.00000827●●●●●●
120. 67064722 c.1096T>C p.F366L missense 0.00000827●●●●●●
121. 67049355 c.533T>C p.I178T missense 0.00000827●●●●●●
122. 67064801 c.1175C>T p.P392L missense 0.00000827●●●●●●
123. 67066548 c.1503T>G p.S501R missense 0.00000827●●●●●●
124. 67049354 c.532A>G p.I178V missense 0.00000827●●●●●●
125. 67064764 c.1138T>C p.S380P missense 0.00000826●●●●●●
126. 67066535 c.1490G>A p.G497D missense 0.00000826●●●●●●
127. 67064782 c.1156G>C p.A386P missense 0.00000826●●●●●●
128. 67066523 c.1478C>A p.A493E missense 0.00000826●●●●●●
129. 67064735 c.1109A>G p.D370G missense 0.00000826●●●●●●
130. 67066507 c.1462G>T p.A488S missense 0.00000826●●●●●●
131. 67066327 c.1282A>G p.T428A missense 0.00000826●●●●●●
132. 67066534 c.1489G>T p.G497C missense 0.00000826●●●●●●
133. 67064743 c.1117C>A p.P373T missense 0.00000826●●●●●●
134. 67066511 c.1466C>G p.A489G missense 0.00000826●●●●●●
135. 67061929 c.653T>C p.L218P missense 0.00000826●●●●●●
136. 67039670 c.167A>G p.Q56R missense 0.00000825●●●●●●
137. 67066337 c.1292C>T p.P431L missense 0.00000825●●●●●●
138. 67061932 c.656A>G p.Y219C missense 0.00000825●●●●●●
139. 67062577 c.861A>C p.K287N missense 0.00000825●●●●●●
140. 67086811 c.1630A>C p.N544H missense 0.00000825●●●●●●
141. 67062578 c.862A>G p.I288V missense 0.00000825●●●●●●
142. 67061988 c.712G>C p.E238Q missense 0.00000824●●●●●●
143. 67066483 c.1438C>T p.R480W missense 0.00000824●●●●●●
144. 67062597 c.881C>T p.A294V missense 0.00000824●●●●●●
145. 67066417 c.1372C>G p.P458A missense 0.00000824●●●●●●
146. 67066369 c.1324T>C p.Y442H missense 0.00000824●●●●●●
147. 67062070 c.794G>A p.G265E missense 0.00000824●●●●●●
148. 67040658 c.288G>T p.Q96H missense 0.00000824●●●●●●
149. 67062022 c.746A>G p.K249R missense 0.00000824●●●●●●
150. 67061980 c.704G>T p.R235L missense 0.00000824●●●●●●
151. 67039646 c.143G>A p.R48K missense 0.00000824●●●●●●
152. 67040605 c.235C>G p.P79A missense 0.00000824●●●●●●
153. 67062692 c.976T>C p.F326L missense 0.00000824●●●●●●
154. 67086734 c.1553G>A p.G518E missense 0.00000824●●●●●●
155. 67039563 c.60A>C p.L20F missense 0.00000824●●●●●●
156. 67062678 c.962T>C p.I321T missense 0.00000824●●●●●●
157. 67047356 c.473T>C p.V158A missense 0.00000824●●●●●●
158. 67047342 c.459C>G p.H153Q missense 0.00000824●●●●●●
159. 67047254 c.371G>A p.C124Y missense 0.00000824●●●●●●
160. 67047241 c.358G>A p.D120N missense 0.00000824●●●●●●
161. 67066402 c.1357G>T p.A453S missense 0.00000824●●●●●●
162. 67062012 c.736G>A p.A246T missense 0.00000824●●●●●●
163. 67062033 c.757G>A p.D253N missense 0.00000824●●●●●●
164. 67040623 c.253G>C p.V85L missense 0.00000824●●●●●●
165. 67086785 c.1604G>A p.R535H missense 0.00000824●●●●●●
166. 67086734 c.1553G>C p.G518A missense 0.00000824●●●●●●
167. 67062680 c.964C>T p.R322C missense 0.00000824●●●●●●
168. 67047296 c.413A>G p.N138S missense 0.00000824●●●●●●
169. 67066427 c.1382C>T p.P461L missense 0.00000824●●●●●●
170. 67066376 c.1331G>A p.S444N missense 0.00000824●●●●●●
171. 67040664 c.294C>A p.N98K missense 0.00000824●●●●●●
172. 67061989 c.713A>C p.E238A missense 0.00000824●●●●●●
173. 67039573 c.70C>T p.L24F missense 0.00000824●●●●●●
174. 67039552 c.49A>G p.M17V missense 0.00000824●●●●●●
175. 67086757 c.1576G>A p.G526S missense 0.00000824●●●●●●
176. 67066484 c.1439G>A p.R480Q missense 0.00000824●●●●●●
177. 67066475 c.1430C>T p.S477L missense 0.00000824●●●●●●
178. 67062587 c.871G>A p.A291T missense 0.00000824●●●●●●
179. 67047256 c.373G>A p.E125K missense 0.00000824●●●●●●
180. 67047242 c.359A>T p.D120V missense 0.00000824●●●●●●
181. 67066417 c.1372C>A p.P458T missense 0.00000824●●●●●●
182. 67062051 c.775T>A p.S259T missense 0.00000824●●●●●●
183. 67039609 c.106C>T p.P36S missense 0.00000824●●●●●●
184. 67061943 c.667G>A p.E223K missense 0.00000824●●●●●●
185. 67039655 c.152C>T p.A51V missense 0.00000824●●●●●●
186. 67062641 c.925C>T p.H309Y missense 0.00000824●●●●●●
187. 67047331 c.448T>A p.F150I missense 0.00000824●●●●●●
188. 67062010 c.734G>A p.R245H missense 0.00000824●●●●●●
189. 67040690 c.320T>A p.I107N missense 0.00000824●●●●●●
190. 67066432 c.1387A>G p.S463G missense 0.00000824●●●●●●
191. 67062082 c.806T>C p.M269T missense 0.00000824●●●●●●
192. 67062003 c.727C>T p.H243Y missense 0.00000824●●●●●●
193. 67039576 c.73A>C p.I25L missense 0.00000824●●●●●●
194. 67066486 c.1441A>C p.K481Q missense 0.00000824●●●●●●
195. 67066475 c.1430C>G p.S477W missense 0.00000824●●●●●●
196. 67062596 c.880G>T p.A294S missense 0.00000824●●●●●●
197. 67047287 c.404A>G p.Y135C missense 0.00000824●●●●●●
198. 67066364 c.1319T>G p.L440W missense 0.00000824●●●●●●
199. 67062054 c.778A>G p.K260E missense 0.00000824●●●●●●
200. 67040638 c.268C>A p.H90N missense 0.00000824●●●●●●
201. 67066388 c.1343G>T p.G448V missense 0.00000824●●●●●●
202. 67039645 c.142A>G p.R48G missense 0.00000824●●●●●●
203. 67039661 c.158A>G p.D53G missense 0.00000824●●●●●●
204. 67086724 c.1543C>T p.P515S missense 0.00000824●●●●●●
205. 67039556 c.53A>G p.D18G missense 0.00000824●●●●●●
206. 67062643 c.927C>A p.H309Q missense 0.00000824●●●●●●
207. 67047341 c.458A>G p.H153R missense 0.00000824●●●●●●
208. 67040707 c.337A>G p.T113A missense 0.00000824●●●●●●
209. 67062665 c.949G>A p.E317K missense 0.00000824●●●●●●
210. 67047348 c.465C>G p.D155E missense 0.00000824●●●●●●
211. 67066438 c.1393G>A p.G465S missense 0.00000824●●●●●●
212. 67062028 c.752A>G p.Y251C missense 0.00000824●●●●●●
213. 67086781 c.1600G>C p.A534P missense 0.00000824●●●●●●
214. 67039597 c.94A>T p.M32L missense 0.00000824●●●●●●
215. 67086712 c.1531T>C p.F511L missense 0.00000824●●●●●●

* This highlights the relative frequency of the variant in the ExAC populations - Non-Finnish European, African, East Asian, South Asian, American and Finnish. Higher frequencies are denoted by darker shades of green, variants absent in a population are coloured light gray.

✝ Genomic coordinates refer to the GRCh37 release of the human genome.