TRIM63 missense variants in ExAC

TRIM63 gene summary
TRIM63 variants in

The table below lists the TRIM63 missense variants found in the ExAC population database. Click on each variant for more details, including presence in the 1000 Genomes and Exome Sequencing Project databases, a breakdown by ethnic class and the variant's role in inherited cardiac disease. Use the form below to customise the variant selection. The table can be sorted by variant location, variant type or ExAC frequency.




No. Genomic coord.✝ Variant (CDS)▼ Variant (Protein) Variant Type▼ ExAC frequency▼Populations*
1. 26385003 c.709A>G p.K237E missense 0.19212326●●●●●●
2. 26384907 c.805G>A p.E269K missense 0.00337053●●●●●●
3. 26393843 c.143C>T p.A48V missense 0.00125778●●●●●●
4. 26385068 c.644C>T p.T215M missense 0.00033044●●●●●●
5. 26380423 c.1012G>T p.D338Y missense 0.00028924●●●●●●
6. 26392916 c.175T>C p.W59R missense 0.00022137●●●●●●
7. 26385059 c.653C>T p.A218V missense 0.00020635●●●●●●
8. 26383717 c.956T>C p.L319P missense 0.00014831●●●●●●
9. 26387820 c.338C>T p.P113L missense 0.00014138●●●●●●
10. 26387780 c.378A>T p.E126D missense 0.00014015●●●●●●
11. 26392867 c.224G>A p.C75Y missense 0.00013513●●●●●●
12. 26392777 c.314A>G p.Y105C missense 0.00011545●●●●●●
13. 26392870 c.221G>A p.R74H missense 0.00010183●●●●●●
14. 26392828 c.263G>C p.G88A missense 0.00009084●●●●●●
15. 26386818 c.536C>T p.A179V missense 0.00007418●●●●●●
16. 26392921 c.170C>T p.P57L missense 0.00006930●●●●●●
17. 26392856 c.235C>T p.R79C missense 0.00006691●●●●●●
18. 26385080 c.632A>G p.Q211R missense 0.00006618●●●●●●
19. 26387768 c.390C>G p.I130M missense 0.00006594●●●●●●
20. 26385024 c.688C>T p.R230W missense 0.00005767●●●●●●
21. 26383741 c.932A>G p.D311G missense 0.00005766●●●●●●
22. 26392871 c.220C>T p.R74C missense 0.00005091●●●●●●
23. 26387695 c.463G>A p.E155K missense 0.00004950●●●●●●
24. 26392876 c.215G>A p.R72H missense 0.00004267●●●●●●
25. 26392873 c.218T>C p.F73S missense 0.00004250●●●●●●
26. 26387824 c.334C>T p.R112W missense 0.00004176●●●●●●
27. 26386831 c.523T>C p.S175P missense 0.00004122●●●●●●
28. 26386806 c.548G>A p.R183H missense 0.00004121●●●●●●
29. 26383715 c.958A>G p.R320G missense 0.00004120●●●●●●
30. 26384981 c.731C>T p.A244V missense 0.00004118●●●●●●
31. 26387724 c.434G>A p.C145Y missense 0.00003296●●●●●●
32. 26383789 c.884T>C p.L295P missense 0.00003296●●●●●●
33. 26387733 c.425G>A p.C142Y missense 0.00003296●●●●●●
34. 26393918 c.68G>A p.C23Y missense 0.00003296●●●●●●
35. 26384986 c.726C>G p.I242M missense 0.00003295●●●●●●
36. 26392907 c.184C>T p.R62W missense 0.00002784●●●●●●
37. 26392855 c.236G>A p.R79H missense 0.00002500●●●●●●
38. 26386770 c.584G>A p.R195H missense 0.00002474●●●●●●
39. 26386767 c.587G>A p.R196Q missense 0.00002474●●●●●●
40. 26387788 c.370G>C p.E124Q missense 0.00002474●●●●●●
41. 26393945 c.41T>C p.M14T missense 0.00002473●●●●●●
42. 26384124 c.849C>G p.I283M missense 0.00001750●●●●●●
43. 26392883 c.208G>A p.G70R missense 0.00001725●●●●●●
44. 26387823 c.335G>A p.R112Q missense 0.00001667●●●●●●
45. 26385068 c.644C>A p.T215K missense 0.00001652●●●●●●
46. 26383816 c.857T>C p.I286T missense 0.00001652●●●●●●
47. 26393972 c.14C>T p.S5L missense 0.00001652●●●●●●
48. 26392835 c.256C>T p.R86C missense 0.00001652●●●●●●
49. 26387801 c.357C>A p.H119Q missense 0.00001651●●●●●●
50. 26392811 c.280A>G p.R94G missense 0.00001650●●●●●●
51. 26392766 c.325T>A p.C109S missense 0.00001650●●●●●●
52. 26393879 c.107T>C p.I36T missense 0.00001649●●●●●●
53. 26385039 c.673A>G p.S225G missense 0.00001649●●●●●●
54. 26386782 c.572T>C p.L191P missense 0.00001649●●●●●●
55. 26386828 c.526A>T p.M176L missense 0.00001649●●●●●●
56. 26386771 c.583C>T p.R195C missense 0.00001649●●●●●●
57. 26383708 c.965T>C p.I322T missense 0.00001648●●●●●●
58. 26384907 c.805G>C p.E269Q missense 0.00001648●●●●●●
59. 26383780 c.893C>T p.T298I missense 0.00001648●●●●●●
60. 26387742 c.416T>A p.V139E missense 0.00001648●●●●●●
61. 26384975 c.737T>A p.I246N missense 0.00001647●●●●●●
62. 26385012 c.700G>A p.E234K missense 0.00001647●●●●●●
63. 26385017 c.695C>T p.T232M missense 0.00001647●●●●●●
64. 26384985 c.727G>A p.E243K missense 0.00001647●●●●●●
65. 26392927 c.164C>T p.A55V missense 0.00001035●●●●●●
66. 26392913 c.178A>C p.T60P missense 0.00000951●●●●●●
67. 26392904 c.187G>A p.G63S missense 0.00000920●●●●●●
68. 26384129 c.844C>A p.L282I missense 0.00000876●●●●●●
69. 26384129 c.844C>T p.L282F missense 0.00000876●●●●●●
70. 26392877 c.214C>T p.R72C missense 0.00000854●●●●●●
71. 26387658 c.500A>G p.K167R missense 0.00000834●●●●●●
72. 26387821 c.337C>G p.P113A missense 0.00000833●●●●●●
73. 26392848 c.243G>T p.E81D missense 0.00000831●●●●●●
74. 26387665 c.493G>A p.G165R missense 0.00000831●●●●●●
75. 26385103 c.609C>A p.H203Q missense 0.00000830●●●●●●
76. 26393980 c.6T>A p.D2E missense 0.00000828●●●●●●
77. 26392843 c.248T>A p.I83N missense 0.00000828●●●●●●
78. 26393978 c.8A>T p.Y3F missense 0.00000827●●●●●●
79. 26387808 c.350G>T p.G117V missense 0.00000827●●●●●●
80. 26392830 c.261C>G p.H87Q missense 0.00000826●●●●●●
81. 26380416 c.1019A>G p.E340G missense 0.00000826●●●●●●
82. 26393853 c.133C>T p.R45W missense 0.00000826●●●●●●
83. 26392829 c.262G>C p.G88R missense 0.00000826●●●●●●
84. 26385062 c.650A>G p.Y217C missense 0.00000826●●●●●●
85. 26393874 c.112C>T p.P38S missense 0.00000825●●●●●●
86. 26387793 c.365G>T p.C122F missense 0.00000825●●●●●●
87. 26387701 c.457G>T p.A153S missense 0.00000825●●●●●●
88. 26393959 c.27G>C p.Q9H missense 0.00000825●●●●●●
89. 26392792 c.299A>G p.N100S missense 0.00000825●●●●●●
90. 26386770 c.584G>T p.R195L missense 0.00000825●●●●●●
91. 26392822 c.269A>T p.Y90F missense 0.00000825●●●●●●
92. 26392798 c.293T>A p.V98E missense 0.00000825●●●●●●
93. 26384891 c.821C>T p.T274I missense 0.00000825●●●●●●
94. 26385050 c.662A>T p.D221V missense 0.00000825●●●●●●
95. 26383694 c.979G>T p.D327Y missense 0.00000825●●●●●●
96. 26392810 c.281G>A p.R94K missense 0.00000825●●●●●●
97. 26387697 c.461G>A p.C154Y missense 0.00000825●●●●●●
98. 26392786 c.305T>A p.I102N missense 0.00000825●●●●●●
99. 26384898 c.814G>A p.G272R missense 0.00000825●●●●●●
100. 26385038 c.674G>A p.S225N missense 0.00000824●●●●●●
101. 26385000 c.712A>G p.K238E missense 0.00000824●●●●●●
102. 26384962 c.750G>C p.Q250H missense 0.00000824●●●●●●
103. 26383729 c.944T>C p.I315T missense 0.00000824●●●●●●
104. 26387765 c.393C>A p.N131K missense 0.00000824●●●●●●
105. 26386815 c.539G>A p.G180E missense 0.00000824●●●●●●
106. 26393944 c.42G>T p.M14I missense 0.00000824●●●●●●
107. 26384915 c.797C>T p.S266F missense 0.00000824●●●●●●
108. 26387782 c.376G>A p.E126K missense 0.00000824●●●●●●
109. 26383730 c.943A>G p.I315V missense 0.00000824●●●●●●
110. 26387707 c.451C>T p.H151Y missense 0.00000824●●●●●●
111. 26386827 c.527T>C p.M176T missense 0.00000824●●●●●●
112. 26384987 c.725T>C p.I242T missense 0.00000824●●●●●●
113. 26387777 c.381T>A p.D127E missense 0.00000824●●●●●●
114. 26383721 c.952G>T p.A318S missense 0.00000824●●●●●●
115. 26383700 c.973G>C p.G325R missense 0.00000824●●●●●●
116. 26393946 c.40A>G p.M14V missense 0.00000824●●●●●●
117. 26383798 c.875G>A p.G292D missense 0.00000824●●●●●●
118. 26386807 c.547C>T p.R183C missense 0.00000824●●●●●●
119. 26387719 c.439G>A p.V147M missense 0.00000824●●●●●●
120. 26385031 c.681G>C p.L227F missense 0.00000824●●●●●●
121. 26384998 c.714G>C p.K238N missense 0.00000824●●●●●●
122. 26387763 c.395T>C p.I132T missense 0.00000824●●●●●●
123. 26384922 c.790A>G p.I264V missense 0.00000824●●●●●●
124. 26384901 c.811G>C p.G271R missense 0.00000824●●●●●●
125. 26383727 c.946G>C p.A316P missense 0.00000824●●●●●●
126. 26393954 c.32G>A p.G11E missense 0.00000824●●●●●●
127. 26393936 c.50T>C p.L17S missense 0.00000824●●●●●●
128. 26387764 c.394A>G p.I132V missense 0.00000824●●●●●●
129. 26380384 c.1051G>A p.G351R missense 0.00000824●●●●●●
130. 26386812 c.542A>T p.N181I missense 0.00000824●●●●●●

* This highlights the relative frequency of the variant in the ExAC populations - Non-Finnish European, African, East Asian, South Asian, American and Finnish. Higher frequencies are denoted by darker shades of green, variants absent in a population are coloured light gray.

✝ Genomic coordinates refer to the GRCh37 release of the human genome.