Paralogue Annotation for CACNA1C residue 1707

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 1707
Reference Amino Acid: V - Valine
Protein Domain: C-terminus


Paralogue Variants mapped to CACNA1C residue 1707

No paralogue variants have been mapped to residue 1707 for CACNA1C.



CACNA1C------------ASED-DIFRRAGGLFGNH>V<-SYYQSDG--------RSAFPQTFT---T-1724
CACNA1AWSPEQGPPTDMPNSQP-NSQSVEMREMGRD>G<-YSDSEHYLPMEGQGRAASMPRLPA-----2099
CACNA1BPPLERGHSTEIPVGRS-GALAVDVQMQSIT>R<RGPDGEPQPGLESQGRAASMPRLAA-----2008
CACNA1D------------EEED-DVFKRNGALLGNH>V<-NHVNSDR--------RDSLQQTNT---T-1727
CACNA1EDPADDGQFQERQSLEP-EVSELKSVQPSNH>G<-IYLPSDTQEHAGSGRASSMPRLTV-----2006
CACNA1F------------EDEK-DLETNKATMVSQP>S<-AR---RG--------SGISVSLPVGDRL-1687
CACNA1GSYMCRHGSTAEGPLGH-RGWGLPKA----->-<--------Q----SGSVLSVHSQP------2086
CACNA1HRPVTQGGSLQSPPRSP-RPASVRT------>-<-------RK----HTFGQRCVSSRP---AA2085
CACNA1IAPPSPFSPDASSPLLP-MPAEFFHPAVSAS>Q<-KGPEKGTG----TGTLPKIALQGS---WA1995
CACNA1S------------AMEE-GIFRRTGGLFGQV>D<-NFL--ER--------TNSLPPVMA---N-1624
SCN10A------------NC-V---L-PDKS----->-<------------------------------1909
SCN11A------------PH-----S-PLQT----->-<------------------------------1772
SCN1A------------NS-I-----TEKT----->-<------------------------------1973
SCN2A------------NS-T-----PEKT----->-<------------------------------1963
SCN3A------------NS-T-----PEKT----->-<------------------------------1958
SCN4A------------NSSS-----PSPE----->-<------------------------------1793
SCN5A------------NF-SRPLG-PPSS----->-<------------------------------1965
SCN7A------------------------------>-<------------------------------
SCN8A------------GT-H-----REKK----->-<------------------------------1935
SCN9A------------NS-S-----PEKT----->-<------------------------------1935
cons                              > <                              

See full Alignment of Paralogues


Known Variants in CACNA1C

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.V1707Ic.5119G>A Putative Benignrs147896322SIFT: tolerated
Polyphen: benign
p.V1707Ac.5120T>C Putative BenignSIFT: tolerated
Polyphen: probably damaging