No paralogue variants have been mapped to residue 1870 for CACNA1C.
| CACNA1C | LSTE------MLSYQDDENRQL-------->T<LPEEDKRDIRQSPKRGFLRSA-SL-GR-R- | 1896 |
| CACNA1A | RSHRASERSLGRYTDV---DTGL------->-<-------GTDLSMTTQSGDLP------SK- | 2194 |
| CACNA1B | RKQRSLEKGPSLSADM---DGAP------->-<-------SSAVGPGLPPGEGPTGC-RRER- | 2103 |
| CACNA1D | QNYGYYSRYPGRNIDSERPRGYHHPQGFLE>D<DDSPVCYDSRRSPRRRLLPPT-PASHR-R- | 1940 |
| CACNA1E | RSYHSSLRLSAHRLNS---DSGH------->-<-------KSDT----------------HR- | 2077 |
| CACNA1F | CSVL----------------LP-------->P<HRAQRYMDGHLVPRRRLLPPT-PA-GR-K- | 1800 |
| CACNA1G | -------------------AQQ-------->H<SR------SHSKISKHMTPPA-PCPGP-E- | 2201 |
| CACNA1H | ------------------------------>-<--------------------G-PEASP-V- | 2125 |
| CACNA1I | ------------------------------>-<-------------RRALGPPA-PAPGP-R- | 2056 |
| CACNA1S | FSSVHYEREFPEETET-------------->-<---------PATRGRALGQPCRVL-GP-H- | 1714 |
| SCN10A | ------------------------------>-<----------------------RG-LSDR- | 1931 |
| SCN11A | ------------------------------>-<----------------------SF-GVAK- | 1785 |
| SCN1A | ------------------------------>-<----------------------KP-IVEK- | 1996 |
| SCN2A | ------------------------------>-<----------------------KP-EKEK- | 1985 |
| SCN3A | ------------------------------>-<----------------------KP-DKEK- | 1980 |
| SCN4A | ------------------------------>-<----------------------IS-PSDTA | 1816 |
| SCN5A | ------------------------------>-<----------------------RA-TSDN- | 1987 |
| SCN7A | ------------------------------>-<----------------------------K- | 1675 |
| SCN8A | ------------------------------>-<----------------------KP-EKEK- | 1957 |
| SCN9A | ------------------------------>-<----------------------KP-DKEK- | 1957 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.T1870M | c.5609C>T | Benign | rs201777030 | SIFT: tolerated Polyphen: possibly damaging |