No paralogue variants have been mapped to residue 1905 for CACNA1C.
| CACNA1C | IRQSPKRGFLRSA-SL-GR-R-ASFHLECL>K<RQKDRGGDIS-----Q-------------- | 1916 |
| CACNA1A | TDLSMTTQSGDLP------SK-ERDQERGR>P<KDR--------------------------- | 2206 |
| CACNA1B | SAVGPGLPPGEGPTGC-RRER-ERRQERGR>S<QERRQPSSSSS----EKQRFYSCDRFGGRE | 2138 |
| CACNA1D | SRRSPRRRLLPPT-PASHR-R-SSFNFECL>R<RQSSQEEVPSSPIFPH-------------- | 1965 |
| CACNA1E | SDT----------------HR-SGGRERGR>S<KERKHLLSPDV----SRCN--SEER-GTQA | 2109 |
| CACNA1F | GHLVPRRRLLPPT-PA-GR-K-PSFTIQCL>Q<RQGSCEDLPIPGTY---------------- | 1823 |
| CACNA1G | SHSKISKHMTPPA-PCPGP-E-PNWGKGPP>E<TRSSLELDTE-------------------- | 2220 |
| CACNA1H | ------------G-PEASP-V-AGGE---->-<------------------------------ | 2129 |
| CACNA1I | -----RRALGPPA-PAPGP-R-AGLS---->-<------------------------------ | 2060 |
| CACNA1S | -PATRGRALGQPCRVL-GP-H-SKPCVEML>K<G----------------------------- | 1724 |
| SCN10A | --------------RG-LSDR-VNMRT--->-<------------------------------ | 1936 |
| SCN11A | --------------SF-GVAK--------->-<------------------------------ | 1785 |
| SCN1A | --------------KP-IVEK-HE------>-<------------------------------ | 1998 |
| SCN2A | --------------KP-EKEK-FE------>-<------------------------------ | 1987 |
| SCN3A | --------------KP-DKEK-FE------>-<------------------------------ | 1982 |
| SCN4A | --------------IS-PSDTAWP------>-<------------------------------ | 1818 |
| SCN5A | --------------RA-TSDN-LQVRG--->-<------------------------------ | 1992 |
| SCN7A | --------------------K--------->-<------------------------------ | 1675 |
| SCN8A | --------------KP-EKEK-QQRAE--->-<------------------------------ | 1962 |
| SCN9A | --------------KP-DKEK-YE------>-<------------------------------ | 1959 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.K1905R | c.5714A>G | Putative Benign | rs375147582 | SIFT: tolerated Polyphen: benign |