Paralogue Annotation for CACNA1C residue 1959

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 1959
Reference Amino Acid: P - Proline
Protein Domain: C-terminus

Paralogue Variants mapped to CACNA1C residue 1959

No paralogue variants have been mapped to residue 1959 for CACNA1C.

CACNA1C	-----------QRSHSPASFPRPFATPPAT>P<GSRGWPPQPVPTLRLEGVESSEKLNSSFPS	1989
CACNA1A	-----HHHHHHHHPPPPDKDRYAQ-ERPDH>G<------RARARDQRWS--------------	2247
CACNA1B	GSGSVNGSPLLSTSGASTPGRGGRRQLPQT>P<------LTPRPSITYKTANS----S--PIH	2213
CACNA1D	-----------AQKYSPSHSTRSWATPPAT>P<PYRDWTPCYTPLIQVEQSEALDQVNGSLPS	2038
CACNA1E	GTGSLSESSIPSVSDTSTP-RRSRRQLPPV>P<------PKPRPLLSYSSLIR----H--AGS	2181
CACNA1F	-----------GRNSGPNRAQGSWATPPQR>G<-----RLLYAPLLLVEEGAAGEGYLGRS--	1868
CACNA1G	----------------------SWISGDLL>P<PGGQEEPPSPRDLKKCYSVEAQSCQRRPTS	2260
CACNA1H	------------------------------>-<----------RDLRRLYSVDAQGFLDKPGR	2149
CACNA1I	------------------------------>-<----------PAARRRLSLRGRGLFSLRG-	2079
CACNA1S	-----------QAPPAPCQCP--------->-<-------------RVESSMPEDRKSSTPGS	1761
SCN10A	------------------------------>-<-------S---S--SIQNED-------E--	1945
SCN11A	------------------------------>-<-----------G--KVHC------------	1790
SCN1A	------------------------------>-<-------Q---E--GKDEKA----------	2006
SCN2A	------------------------------>-<-------K---D--KSEKED----------	1995
SCN3A	------------------------------>-<-------K---D--KPEKES----------	1990
SCN4A	------------------------------>-<-------P---A--PPPGQT----------	1826
SCN5A	------------------------------>-<-------S---D--YSHSED-------L--	2001
SCN7A	------------------------------>-<-----------S--P---------------	1677
SCN8A	------------------------------>-<-------E---G--RRERAK----------	1970
SCN9A	------------------------------>-<-------Q---D--RTEKED----------	1967
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See full Alignment of Paralogues

Known Variants in CACNA1C

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.P1959A	c.5875C>G	Putative Benign			SIFT: Polyphen:
p.P1959S	c.5875C>T	Putative Benign			SIFT: Polyphen:
p.P1959L	c.5876C>T	Putative Benign			SIFT: Polyphen: