Paralogue Annotation for CACNA1C residue 2071

Residue details

Gene: CACNA1C
Reference Sequences: LRG: LRG_334, Ensembl variant: ENST00000399655 / ENSP00000382563
Amino Acid Position: 2071
Reference Amino Acid: I - Isoleucine
Protein Domain: C-terminus

Paralogue Variants mapped to CACNA1C residue 2071

No paralogue variants have been mapped to residue 2071 for CACNA1C.

CACNA1C	-----------PKFIEVTT-QELADACDMT>I<EEMESAADNILSGGAPQSPNGALLPFVNCR	2101
CACNA1A	------------------------------>-<------------------------------
CACNA1B	-----------SDPYLGQR-LDSEASVHAL>P<EDTLTFEEAVATNSGRSSRTSYVSSLTSQS	2305
CACNA1D	-----------PKFVSATK-HEIADACDLT>I<DEMESAASTLLNGNVRPRANGDVGPLSHRQ	2146
CACNA1E	-----------SEPYLALH-EDSHAS-DCG>E<EETLTFEAAVATSLGRSNTIGSAPPLRHSW	2276
CACNA1F	-----------PRFVALAK-QEIADACRLT>L<DEMDNAASDLLAQGTSS-------------	1950
CACNA1G	-----------PPSPGICLRRRAPSSDSKD>P<LASGPPDSMAASPSPKKDVLSLSGLSSDPA	2373
CACNA1H	DPAAKGERWGQASCRAEHLTVPSFAFEPLD>L<GVPSGDPFLDGSHSVTPESRASSSGAIVPL	2303
CACNA1I	-----------PPAPGLTPARKFSSTSSLA>A<PGRPHAAALAHGLARSPSWAADRSKDPPGR	2191
CACNA1S	-----------ANFIMATG-QALADACQME>P<EEVEIMATELLKGREAPEGMASSLGCLNL-	1851
SCN10A	------------------------------>-<------------------------------
SCN11A	------------------------------>-<------------------------------
SCN1A	------------------------------>-<------------------------------
SCN2A	------------------------------>-<------------------------------
SCN3A	------------------------------>-<------------------------------
SCN4A	------------------------------>-<------------------------------
SCN5A	------------------------------>-<------------------------------
SCN7A	------------------------------>-<------------------------------
SCN8A	------------------------------>-<------------------------------
SCN9A	------------------------------>-<------------------------------
cons	> <

See full Alignment of Paralogues

Known Variants in CACNA1C

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.I2071T	c.6212T>C	Putative Benign			SIFT: Polyphen: