No paralogue variants have been mapped to residue 745 for CACNA1C.
| CACNA1C | GIMAYGGPSFPGMLVCIYFIILFICGNYIL>L<NVFLAIAVDNLADAESLTSAQKEEEEE-KE | 774 |
| CACNA1A | GIKSQGGV-QGGMVFSIYFIVLTLFGNYTL>L<NVFLAIAVDNLANAQELTKDEQEEEEA-AN | 735 |
| CACNA1B | GIESQGGV-SKGMFSSFYFIVLTLFGNYTL>L<NVFLAIAVDNLANAQELTKDEEEMEEA-AN | 731 |
| CACNA1D | GIMAYGGPSSSGMIVCIYFIILFICGNYIL>L<NVFLAIAVDNLADAESLNTAQKEEAEE-KE | 793 |
| CACNA1E | GIRSQGGV-SSGMWSAIYFIVLTLFGNYTL>L<NVFLAIAVDNLANAQELTKDEQEEEEA-FN | 724 |
| CACNA1F | GIMAYGGPFFPGMLVCIYFIILFICGNYIL>L<NVFLAIAVDNLASGDA-GTAKDKGGEK-SN | 778 |
| CACNA1G | GMAS-T-S----SWAALYFIALMTFGNYVL>F<NLLVAILVEGFQ-AEEISKREDASGQL-SC | 984 |
| CACNA1H | GMAS-T-S----SWAALYFVALMTFGNYVL>F<NLLVAILVEGFQ-AEGDANRSDTDEDKTSV | 1036 |
| CACNA1I | GMAS-T-S----PWASLYFVALMTFGNYVL>F<NLLVAILVEGFQAEGDAN-RSYSDEDQSSS | 883 |
| CACNA1S | GIMAYGGPSYPGMLVCIYFIILFVCGNYIL>L<NVFLAIAVDNLAEAESLTSAQKAKAEE-KK | 682 |
| SCN10A | CMEV-----GQKSICLILFLTVMVLGNLVV>L<NLFIALLLNSFS-ADNLTAP-EDDGEV-NN | 909 |
| SCN11A | CMQEAN---ASSSLCVIVFILITVIGKLVV>L<NLFIALLLNSFS-NEERNGNLEGEARK-TK | 831 |
| SCN1A | CMEV-----AGQAMCLTVFMMVMVIGNLVV>L<NLFLALLLSSFS-ADNLAAT-DDDNEM-NN | 1011 |
| SCN2A | CMEV-----AGQTMCLTVFMMVMVIGNLVV>L<NLFLALLLSSFS-SDNLAAT-DDDNEM-NN | 1002 |
| SCN3A | CMEV-----AGQTMCLIVFMLVMVIGNLVV>L<NLFLALLLSSFS-SDNLAAT-DDDNEM-NN | 1003 |
| SCN4A | CMEV-----AGQAMCLTVFLMVMVIGNLVV>L<NLFLALLLSSFS-ADSLAAS-DEDGEM-NN | 821 |
| SCN5A | CMEV-----SGQSLCLLVFLLVMVIGNLVV>L<NLFLALLLSSFS-ADNLTAP-DEDREM-NN | 958 |
| SCN7A | CMEV-----AGQSWCIPFYLMVILIGNLLV>L<YLFLA-LVSSFS-SCKDVTA-EENNEA-KN | 747 |
| SCN8A | CMEV-----AGQAMCLIVFMMVMVIGNLVV>L<NLFLALLLSSFS-ADNLAAT-DDDGEM-NN | 996 |
| SCN9A | CMEV-----AGQAMCLIVYMMVMVIGNLVV>L<NLFLALLLSSFS-SDNLTAI-EEDPDA-NN | 976 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.Leu745Pro | c.2234T>C | Unknown | SIFT: Polyphen: |