No paralogue variants have been mapped to residue 81 for CACNA1C.
| CACNA1C | WQAAIDAARQAKLMGSAGNATISTVSST-Q>R<KRQQYG-KPKKQGSTTATRPPRALLCLTLK | 110 |
| CACNA1A | ------PGA-----------QRMYKQSMAQ>R<ARTMAL-YNPIPVRQNCLTVNRSLFLFSED | 84 |
| CACNA1B | ------PGQ-----------RVLYKQSIAQ>R<ARTMAL-YNPIPVKQNCFTVNRSLFVFSED | 81 |
| CACNA1D | WQAAIDAARQAKAAQTMSTSAPPPVGSLSQ>R<KRQQYA-KSKKQGNSSNSRPARALFCLSLN | 112 |
| CACNA1E | ------SGQ-----------AAAYKQTKAQ>R<ARTMAL-YNPIPVRQNCFTVNRSLFIFGED | 75 |
| CACNA1F | -------AV--------EGESSGASGLGTP>K<RRNQHS-KHKTVAVASAQRSPRALFCLTLA | 78 |
| CACNA1G | -------G-----------PGSA------->E<KDPG-SADSEAEGLPYPALAPVVFFYLSQD | 67 |
| CACNA1H | -------S-----------P-AA------->E<RGAELG-ADEEQRVPYPALAATVFFCLGQT | 86 |
| CACNA1I | ------PS-----------SPPG------->L<EEPL-D-G-ADPHVPHPDLAPIAFFCLRQT | 65 |
| CACNA1S | --------------------------SSPQ>D<EGLRKK-QPKKPVPEILPRPPRALFCLTLE | 37 |
| SCN10A | KACNQLPKFYGELPAELIGEPLEDLDPFYS>T<HR-TFM-VLNKGRTISRFSATRALWLFSPF | 116 |
| SCN11A | KASRKLPKLYGDIPRELIGKPLEDLDPFYR>N<HK-TFM-VLNRKRTIYRFSAKHALFIFGPF | 115 |
| SCN1A | EAGKNLPFIYGDIPPEMVSEPLEDLDPYYI>N<KK-TFI-VLNKGKAIFRFSATSALYILTPF | 114 |
| SCN2A | EAGKSLPFIYGDIPPEMVSVPLEDLDPYYI>N<KK-TFI-VLNKGKAISRFSATPALYILTPF | 115 |
| SCN3A | EAGKNLPFIYGDIPPEMVSEPLEDLDPYYI>N<KK-TFI-VMNKGKAIFRFSATSALYILTPL | 114 |
| SCN4A | EAGKNLPMIYGDPPPEVIGIPLEDLDPYYS>N<KK-TFI-VLNKGKAIFRFSATPALYLLSPF | 117 |
| SCN5A | QASKKLPDLYGNPPQELIGEPLEDLDPFYS>T<QK-TFI-VLNKGKTIFRFSATNALYVLSPF | 117 |
| SCN7A | EVGKKLPFIYGNLSQGMVSEPLEDVDPYYY>K<KKNTFI-VLNKNRTIFRFNAASILCTLSPF | 104 |
| SCN8A | EAGKSLPFIYGDIPQGLVAVPLEDFDPYYL>T<QK-TFV-VLNRGKTLFRFSATPALYILSPF | 118 |
| SCN9A | EAGKQLPFIYGDIPPGMVSEPLEDLDPYYA>D<KK-TFI-VLNKGKTIFRFNATPALYMLSPF | 112 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.R81W | c.241C>T | Putative Benign | SIFT: Polyphen: | ||
| p.Arg81Gln | c.242G>A | Unknown | SIFT: Polyphen: |