No paralogue variants have been mapped to residue 850 for CACNA1C.
| CACNA1C | EDK----SPYPNP---ET-----TGEEDEE>E<P----------------------------- | 851 |
| CACNA1A | ------------------------------>-<------RHGAPATYEGDARREDKERRHRRR | 1030 |
| CACNA1B | ------------------------------>-<------RARHKAQPAHEAVEKETT------ | 998 |
| CACNA1D | EDK----DPYPPC---DVPVGEEEEEEEED>E<P----------------------------- | 857 |
| CACNA1E | ------------EADTPL-----VLPHPEL>E<VGKHVVLTEQEPEGSSEQALLGNVQLD--- | 1041 |
| CACNA1F | E-G----ARREGA---DMEEEEEEEEEEEE>E<E----------------------------- | 822 |
| CACNA1G | LARALRPDD---P---PL-----DGDDADD>E<G----------------------------- | 1228 |
| CACNA1H | SDFFLRIDS---H---RE-----DAAELDD>D<S----------------------------- | 1246 |
| CACNA1I | KDVFTKMGD-------RG-----DRGEDEE>E<I----------------------------- | 1122 |
| CACNA1S | EVK----DPYPSA---DF-----PGDDEED>E<P----------------------------- | 750 |
| SCN10A | ----------------E-----TWKDESVP>Q<V-------------PA---E---------- | 1076 |
| SCN11A | ----------------------NAQRITQP>E<P-------------EQQAYEL--------- | 949 |
| SCN1A | ----------------------DFSSESDL>E<E-------------SK---E---------- | 1143 |
| SCN2A | ----------------------EFSSESDM>E<E-------------SK---E---------- | 1133 |
| SCN3A | ----------------------EFSSESEL>E<E-------------SK---E---------- | 1131 |
| SCN4A | ----------------------ETDTFSEP>E<D-------------SKKPPQ---------- | 955 |
| SCN5A | ----------------------EENSLGTE>E<E-------------SSKQQESQPVS----- | 1083 |
| SCN7A | ----------------------EIQSKSGD>G<G-------------SK---E---------- | 864 |
| SCN8A | ----------------------DVSSESDP>E<G-------------SK---D---------- | 1124 |
| SCN9A | ----------------------ELSSDSDS>E<Y-------------SK---V---------- | 1106 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.E850D | c.2550G>C | Putative Benign | SIFT: Polyphen: |