Paralogue Annotation for KCNE1 residue 105

Residue details

Gene: KCNE1
Reference Sequences: LRG: LRG_290, Ensembl variant: ENST00000399289 / ENSP00000382228
Amino Acid Position: 105
Reference Amino Acid: S - Serine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNE1 residue 105

No paralogue variants have been mapped to residue 105 for KCNE1.



KCNE1DPFNVYIESDA-WQEKDKAYVQARVLESYR>S<CYVV-------------------------E110
KCNE2DPYHQYIVED--WQEKYKSQILNL------>-<-----------------------------E104
KCNE3DPYHVYIKN--------------------->-<------------------------------98
KCNE4SLLLLYKDEERLWGEAMKPLPVVSGLRSVQ>V<PLMLNMLQESVAPALSCTLCSMEGDSVSSE128
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNE1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.S105Lc.314C>T Putative BenignSIFT:
Polyphen:
ReportsUnknown Novel genotype-phenotype associations demonstrated by high-throughput sequencing in patients with hypertrophic cardiomyopathy. Heart. 2015 101(4):294-301. doi: 10.1136/heartjnl-2014-306387. 25351510