Paralogue Annotation for KCNE1 residue 6

Residue details

Gene: KCNE1
Reference Sequences: LRG: LRG_290, Ensembl variant: ENST00000399289 / ENSP00000382228
Amino Acid Position: 6
Reference Amino Acid: T - Threonine
Protein Domain: N-terminus


Paralogue Variants mapped to KCNE1 residue 6

No paralogue variants have been mapped to residue 6 for KCNE1.



KCNE1--MILS---N>T<TAVTPFLTKLWQE---T------VQQGGN-26
KCNE2MSTLSN---F>T<QTLEDVFRRIFITYMDNW----RQNTTAEQ34
KCNE3METTNGTETW>Y<ESLHAVLKALNATLHSNLLCRPGPGLGPD-40
KCNE4---------->-<--------MLKMEPLNST----HPGTAASS18
cons          > <                              

See full Alignment of Paralogues


Known Variants in KCNE1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.T6Nc.17C>A UnknownSIFT:
Polyphen:
ReportsUnknown Novel genotype-phenotype associations demonstrated by high-throughput sequencing in patients with hypertrophic cardiomyopathy. Heart. 2015 101(4):294-301. doi: 10.1136/heartjnl-2014-306387. 25351510