Paralogue Annotation for KCNE1 residue 91

Residue details

Gene: KCNE1
Reference Sequences: LRG: LRG_290, Ensembl variant: ENST00000399289 / ENSP00000382228
Amino Acid Position: 91
Reference Amino Acid: D - Aspartate
Protein Domain: C-terminus

Paralogue Variants mapped to KCNE1 residue 91

No paralogue variants have been mapped to residue 91 for KCNE1.

KCNE1	MLSYIRSKKLEHSNDPFNVYIESDA-WQEK>D<KAYVQARVLESYRSCYVV------------	109
KCNE2	LVSTVKSKRREHSNDPYHQYIVED--WQEK>Y<KSQILNL-----------------------	103
KCNE3	ILGYTRSRKVDKRSDPYHVYIKN------->-<------------------------------	98
KCNE4	MLGYMKSKRREKKSSLLLLYKDEERLWGEA>M<KPLPVVSGLRSVQVPLMLNMLQESVAPALS	114
cons	> <

See full Alignment of Paralogues

Known Variants in KCNE1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.D91E	c.273C>A	Inherited Arrhythmia	LQTS	rs146614850	SIFT: tolerated Polyphen: benign
Reports		Inherited Arrhythmia	LQTS	Long QT syndrome in South Africa: the results of comprehensive genetic screening. Cardiovasc J Afr. 2013 24(6):231-7. doi: 10.5830/CVJA-2013-032. 24217263
p.D91N	c.271G>A	Putative Benign			SIFT: Polyphen: