Paralogue Annotation for KCNE2 residue 94

Residue details

Gene: KCNE2
Reference Sequences: LRG: LRG_291, Ensembl variant: ENST00000290310 / ENSP00000290310
Amino Acid Position: 94
Reference Amino Acid: E - Glutamate
Protein Domain: C-terminus

Paralogue Variants mapped to KCNE2 residue 94

No paralogue variants have been mapped to residue 94 for KCNE2.

KCNE2	AILVSTVKSKRREHSNDPYHQYIVED--WQ>E<KYKSQILNL---------------------	103
KCNE1	GIMLSYIRSKKLEHSNDPFNVYIESDA-WQ>E<KDKAYVQARVLESYRSCYVV----------	109
KCNE3	SLILGYTRSRKVDKRSDPYHVYIKN----->-<------------------------------	98
KCNE4	GIMLGYMKSKRREKKSSLLLLYKDEERLWG>E<AMKPLPVVSGLRSVQVPLMLNMLQESVAPA	112
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See full Alignment of Paralogues

Known Variants in KCNE2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.E94G	c.281A>G	Inherited Arrhythmia	LQTS	rs74424227	SIFT: tolerated Polyphen: benign
Reports		Inherited Arrhythmia	LQTS	Spectrum and prevalence of mutations from the first 2,500 consecutive unrelated patients referred for the FAMILION long QT syndrome genetic test. Heart Rhythm. 2009 6(9):1297-303. 19716085