Paralogue Annotation for KCNH2 residue 1069

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 1069
Reference Amino Acid: R - Arginine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNH2 residue 1069

No paralogue variants have been mapped to residue 1069 for KCNH2.



KCNH2ETRLSADMATVLQ--------------LLQ>R<QMTLVPPAYSAVTTP---------------1084
KCNH1DSCDSGITKSDLR--------------LDN>V<GEARSPQDRSPILAEVKHSF----------914
KCNH3RQAVTELSEQVLQ--------------MRE>G<LQSLRQAVQLVLAPHREGP-----------917
KCNH4NQEISRLNQEVSQ--------------LSR>E<LRHIMGLLQARLGPP---------------915
KCNH5DSCDSGITKSDLR--------------LDK>A<GEARSPLEHSPIQADAKHPF----------898
KCNH6QTPSYGDLDDCSP--------------KHR>N<SSPRMP--HLAVATD---------------926
KCNH7ESQMTTDIQTILQ--------------LLQ>K<QTTVVPPAYSMVTAGSEYQR----------1082
KCNH8NSEVTTLTQEVSQ--------------LGK>D<MRNVIQLLENVLSPQQPSRFCSLHSTSVCP917
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<------------------------------
CNGB1------------------------------>-<------------------------------
CNGB3------------------------------>-<------------------------------
HCN1VRPLSASQPSLPHEVSTLISRPHPTVG--->-<ESLASIPQPVTAVPGTGLQ-----------828
HCN2SRPLSASQPSLPHGAPGPAASTRPAS---->-<------------------------------842
HCN3GRPLSASQPSLPQRATGDGSPGRKGS---->-<------------------------------734
HCN4LKLISASQPALPQDGAQTLRRASPHSSGES>M<AAFPLFPRAGGGSGGSGS------------1131
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.R1069Sc.3207G>T Putative BenignSIFT:
Polyphen: