Paralogue Annotation for KCNH2 residue 309

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 309
Reference Amino Acid: H - Histidine
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 309

No paralogue variants have been mapped to residue 309 for KCNH2.



KCNH2DIEAM--------RAGVLPPPPRHASTGAM>H<PLRSGLLNSTSDSDLVRYR---TISKIPQI336
KCNH1------------------------------>-<----------------KFA-----------152
KCNH3------------------------------>-<-----------------S------------160
KCNH4------------------------------>-<-----------------A------------161
KCNH5------------------------------>-<----------------KFA-----------150
KCNH6------------------------------>-<------------TGRGKYR---TISQIPQF184
KCNH7DIEGFGVHPKNIFRDRHASEDNGRNVKGPF>N<HIKSSLLGSTSDSNLNKYS---TINKIPQL335
KCNH8------------------------------>-<-----------------A------------156
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<------------------------------
CNGB1ALSPAESPVVAWSDPTTPKDTDGQDRAAST>A<STNSAIINDRLQELVKLFKERTEKV-KEKL586
CNGB3EMDPGKE------GPNSPQNK------PPA>A<PVINEYADAQLHNLVKRMRQRTALY-KKKL150
HCN1------------------------------>-<------------------------------
HCN2------------------------------>-<------------------------------
HCN3------------------------------>-<------------------------------
HCN4------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.H309Qc.927C>A Putative BenignSIFT:
Polyphen: