Paralogue Annotation for KCNH2 residue 311

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 311
Reference Amino Acid: L - Leucine
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 311

No paralogue variants have been mapped to residue 311 for KCNH2.



KCNH2EAM--------RAGVLPPPPRHASTGAMHP>L<RSGLLNSTSDSDLVRYR---TISKIPQITL338
KCNH1------------------------------>-<--------------KFA-------------152
KCNH3------------------------------>-<---------------S--------------160
KCNH4------------------------------>-<---------------A--------------161
KCNH5------------------------------>-<--------------KFA-------------150
KCNH6------------------------------>-<----------TGRGKYR---TISQIPQFTL186
KCNH7EGFGVHPKNIFRDRHASEDNGRNVKGPFNH>I<KSSLLGSTSDSNLNKYS---TINKIPQLTL337
KCNH8------------------------------>-<---------------A--------------156
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<------------------------------
CNGB1SPAESPVVAWSDPTTPKDTDGQDRAASTAS>T<NSAIINDRLQELVKLFKERTEKV-KEKLID588
CNGB3DPGKE------GPNSPQNK------PPAAP>V<INEYADAQLHNLVKRMRQRTALY-KKKLVE152
HCN1------------------------------>-<------------------------------
HCN2------------------------------>-<------------------------------
HCN3------------------------------>-<------------------------------
HCN4------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.L311Rc.932T>G Putative BenignSIFT:
Polyphen: