Paralogue Annotation for KCNH2 residue 326

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 326
Reference Amino Acid: R - Arginine
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 326

No paralogue variants have been mapped to residue 326 for KCNH2.



KCNH2LPPPPRHASTGAMHPLRSGLLNSTSDSDLV>R<YR---TISKIPQITLNFVDLKGDPFLASP-352
KCNH1------------------------------>K<FA------------------RLTRALTSS-161
KCNH3------------------------------>-<S------------------KGFNANRRRS-170
KCNH4------------------------------>-<A-----------------TWKFRSARRRS-172
KCNH5------------------------------>K<FA------------------RLTRALTNS-159
KCNH6--------------------------TGRG>K<YR---TISQIPQFTLNFVEFNLEKHRSSS-200
KCNH7ASEDNGRNVKGPFNHIKSSLLGSTSDSNLN>K<YS---TINKIPQLTLNFSEVKTEKKNSSPP352
KCNH8------------------------------>-<A-----------------GTHFDSARRRS-167
CNGA1------------------------------>-<----------------KKK-KKKEKKSKS-116
CNGA2------------------------------>-<----------------FLE-RFRGPELQT-105
CNGA3------------------------------>-<----------------FPD-RFRGAELKE-109
CNGA4------------------------------>-<-------------------------KVKT-9
CNGB1PKDTDGQDRAASTASTNSAIINDRLQELVK>L<FKERTEKV-KEKLIDPDVTSDEE-SPKPSP602
CNGB3PQNK------PPAAPVINEYADAQLHNLVK>R<MRQRTALY-KKKLVEGDLSS-----PEASP162
HCN1------------------------------>-<--------------------EDAEGPR-R-89
HCN2------------------------------>-<--------------------PAGEPRG-S-158
HCN3------------------------------>-<--------------------PE------P-44
HCN4------------------------------>-<--------------------PEAEVRL-G-209
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.R326Cc.976C>T Putative BenignSIFT:
Polyphen: