Paralogue Annotation for KCNH2 residue 505

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 505
Reference Amino Acid: A - Alanine
Protein Domain: Transmembrane/Linker/Pore


Paralogue Variants mapped to KCNH2 residue 505

No paralogue variants have been mapped to residue 505 for KCNH2.



KCNH2N-ANEEVVSHPGRIAVHYFKGW-FLIDMVA>A<IPFDLLIFGSGSEE----------------519
KCNH1G-PAGEVISDPKLIRMNYLKTW-FVIDLLS>C<LPYDVINAFENVDEVSAFMGDPGKIGFADQ333
KCNH3S-KSGQVVFAPKSICLHYVTTW-FLLDVIA>A<LPFDLLHAF-KVN----------------V327
KCNH4S-QSGQVISAPRSIGLHYLATW-FFIDLIA>A<LPFDLLYIF-NIT----------------V329
KCNH5G-PGGEVISDPKLIRMNYLKTW-FVIDLLS>C<LPYDIINAFENVDEG---------------315
KCNH6N-TNDEVVSHPRRIAVHYFKGW-FLIDMVA>A<IPFDLLIFRTGSDE---------------T368
KCNH7N-QNEEVVSDPAKIAIHYFKGW-FLIDMVA>A<IPFDLLIFGSGSDE---------------T519
KCNH8S-KSGQVIFEARSICIHYVTTW-FIIDLIA>A<LPFDLLYAF-NVT----------------V323
CNGA1E--QGLLVKEELKLINKYKSNLQFKLDVLS>L<IPTDLLYFKLGWNY----------------267
CNGA2E--QGLLVKDTKKLRDNYIHTLQFKLDVAS>I<IPTDLIYFAVDIHS----------------242
CNGA3E--QGLMVSDTNRLWQHYKTTTQFKLDVLS>L<VPTDLAYLKVGTNY----------------270
CNGA4E--QGILVVDKGRISSRYVRTWSFFLDLAS>L<MPTDVVYVRLGPHT----------------136
CNGB1R--GGDIITDKKDMRNNYLKSRRFKMDLLS>L<LPLDFLYLKVGVN-----------------758
CNGB3R--GGDIIVDSNELRKHYRTSTKFQLDVAS>I<IPFDICYLFFGFN-----------------320
HCN1NEDSSEIILDPKVIKMNYLKSW-FVVDFIS>S<IPVDYIFLIVEK--GMDSEVYKTARALR-I256
HCN2IEDNTEIILDPEKIKKKYLRTW-FVVDFVS>S<IPVDYIFLIVEK--GIDSEVYKTARALR-I325
HCN3VEEGAEILLAPRAIRTRYLRTW-FLVDLIS>S<IPVDYIFLVVELEPRLDAEVYKTARALR-I209
HCN4VEDNTEIILDPQRIKMKYLKSW-FMVDFIS>S<IPVDYIFLIVET--RIDSEVYKTARALR-I376
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.A505Vc.1514C>T Putative BenignSIFT:
Polyphen: