No paralogue variants have been mapped to residue 580 for KCNH2.
| KCNH2 | LFLLMCTFALIAHWLACIWYAIGNMEQPHM>D<SR----IGWLHNLGDQIGKPYNSS------ | 600 |
| KCNH1 | LVLLVCVFGLAAHWMACIWYSIGDYEIFDE>D<TKTIRNNSWLYQLAMDIGTPYQFN------ | 433 |
| KCNH3 | LTLLMAVFALLAHWVACVWFYIGQREIESS>E<SELPE-IGWLQELARRLETPYYLVGRRPAG | 419 |
| KCNH4 | LTLLMSVFALLAHWMACIWYVIGRREMEAN>D<PLLWD-IGWLHELGKRLEVPYVNG------ | 415 |
| KCNH5 | LVLLVCVFGLVAHWLACIWYSIGDYEVIDE>V<TNTIQIDSWLYQLALSIGTPYRYN------ | 403 |
| KCNH6 | LFLLMCTFALIAHWLACIWYAIGNVERPYL>E<HK----IGWLDSLGVQLGKRYNGS------ | 451 |
| KCNH7 | LMLLMCIFALIAHWLACIWYAIGNVERPYL>T<DK----IGWLDSLGQQIGKRYNDS------ | 602 |
| KCNH8 | LTLLMSMFALLAHWMACIWYVIGKMEREDN>S<LLKWE-VGWLHELGKRLESPYYGNN----- | 410 |
| CNGA1 | ISNLVMYIVIIIHWNACVFYSISKAIGFGN>D<-------TWVYPD---INDP---------- | 340 |
| CNGA2 | ISNLVLYILVIIHWNACIYYAISKSIGFGV>D<-------TWVYPN---ITDP---------- | 315 |
| CNGA3 | IGNLVLYILIIIHWNACIYFAISKFIGFGT>D<-------SWVYPN---ISIP---------- | 343 |
| CNGA4 | IAKLMLYIFVVIHWNSCLYFALSRYLGFGR>D<-------AWVYPD---PAQP---------- | 209 |
| CNGB1 | VIRTTAYLLYSLHLNSCLYYWASAYQGLGS>T<-------HWVYD------------------ | 826 |
| CNGB3 | VIRTTGYLLFILHINACVYYWASNYEGIGT>T<-------RWVYD------------------ | 388 |
| HCN1 | IFNLIGMMLLLCHWDGCLQFLVPLLQDFPP>D<-------CWVS-----LNEM---------- | 336 |
| HCN2 | ICNLISMMLLLCHWDGCLQFLVPMLQDFPR>N<-------CWVS-----INGM---------- | 405 |
| HCN3 | IFNLIGMMLLLCHWDGCLQFLVPMLQDFPP>D<-------CWVS-----INHM---------- | 289 |
| HCN4 | IVNLIGMMLLLCHWDGCLQFLVPMLQDFPD>D<-------CWVS-----INNM---------- | 456 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.Asp580His | c.1738G>C | Unknown | SIFT: Polyphen: |