Paralogue Annotation for KCNH2 residue 679

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 679
Reference Amino Acid: R - Arginine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNH2 residue 679

No paralogue variants have been mapped to residue 679 for KCNH2.



KCNH2SLMYASIFGNVSAIIQRLYSGTARYHTQML>R<VREFIRFHQIPNPLRQRLEEYFQHAWSYTN709
KCNH1SLLYATIFGNVTTIFQQMYANTNRYHEMLN>S<VRDFLKLYQVPKGLSERVMDYIVSTWSMSR548
KCNH3ALMHAVVFGNVTAIIQRMYARRFLYHSRTR>D<LRDYIRIHRIPKPLKQRMLEYFQATWAVNN550
KCNH4ALMHAVVFGNVTAIIQRMYSRRSLYHSRMK>D<LKDFIRVHRLPRPLKQRMLEYFQTTWAVNS524
KCNH5SLLYATIFGNVTTIFQQMYANTNRYHEMLN>N<VRDFLKLYQVPKGLSERVMDYIVSTWSMSK517
KCNH6SLMYASIFGNVSAIIQRLYSGTARYHTQML>R<VKEFIRFHQIPNPLRQRLEEYFQHAWSYTN561
KCNH7SLMYASIFGNVSAIIQRLYSGTARYHMQML>R<VKEFIRFHQIPNPLRQRLEEYFQHAWTYTN712
KCNH8ALMHALVFGNVTAIIQRMYSRWSLYHTRTK>D<LKDFIRVHHLPQQLKQRMLEYFQTTWSVNN519
CNGA1VLIFATIVGNIGSMISNMNAARAEFQARID>A<IKQYMHFRNVSKDMEKRVIKWFDYLWTNKK446
CNGA2VLIFATIVGNVGSMISNMNATRAEFQAKID>A<VKHYMQFRKVSKGMEAKVIRWFDYLWTNKK421
CNGA3VLIFATIVGNVGSMISNMNASRAEFQAKID>S<IKQYMQFRKVTKDLETRVIRWFDYLWANKK449
CNGA4VMGFATIMGSMSSVIYNMNTADAAFYPDHA>L<VKKYMKLQHVNRKLERRVIDWYQHLQINKK315
CNGB1VFAFSVMIGQMRDVVGAATAGQTYYRSCMD>S<TVKYMNFYKIPKSVQNRVKTWYEYTWHSQG929
CNGB3VFVFSSLIGQMRDVIGAATANQNYFRACMD>D<TIAYMNNYSIPKLVQKRVRTWYEYTWDSQR491
HCN1ATCYAMFVGHATALIQSLDSSRRQYQEKYK>Q<VEQYMSFHKLPADMRQKIHDYYEHRYQG-K442
HCN2ATCYAMFIGHATALIQSLDSSRRQYQEKYK>Q<VEQYMSFHKLPADFRQKIHDYYEHRYQG-K511
HCN3ATCYAMFIGHATALIQSLDSSRRQYQEKYK>Q<VEQYMSFHKLPADTRQRIHEYYEHRYQG-K395
HCN4ATCYAMFIGHATALIQSLDSSRRQYQEKYK>Q<VEQYMSFHKLPPDTRQRIHDYYEHRYQG-K562
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.R679Wc.2035C>T Putative BenignSIFT: deleterious
Polyphen: probably damaging
p.R679Qc.2036G>A Putative BenignSIFT: deleterious
Polyphen: probably damaging