Paralogue Annotation for KCNH2 residue 73

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 73
Reference Amino Acid: R - Arginine
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 73

No paralogue variants have been mapped to residue 73 for KCNH2.



KCNH2YCNDGFCELCGYSRAEVMQRPCTCDFLHGP>R<TQRRAAAQ-IAQ------------------84
KCNH1YSNDGFCKLSGYHRAEVMQKSSTCSFMYGE>L<TDKDTIEK-VRQ------------------85
KCNH3YCSDGFCDLTGFSRAEVMQRGCACSFLYGP>D<TSELVRQQ-IRK------------------85
KCNH4YCSDGFCELTGYGRTEVMQKTCSCRFLYGP>E<TSEPALQR-LHK------------------85
KCNH5YSNDGFCKLSGYHRADVMQKSSTCSFMYGE>L<TDKKTIEK-VRQ------------------83
KCNH6YCNDGFCELFGYSRVEVMQQPCTCDFLTGP>N<TPSSAVSR-LAQ------------------84
KCNH7YCNDGFCEMTGFSRPDVMQKPCTCDFLHGP>E<TKRHDIAQ-IAQ------------------84
KCNH8YCSDGFCELAGFARTEVMQKSCSCKFLFGV>E<TNEQLMLQ-IEK------------------85
CNGA1RMEN-------------------------->-<-------G-ACS------------------40
CNGA2-NHNHHA------PPA-----------IKA>N<GK-DDHRT-SSR------------------37
CNGA3KTSD-----------------------RDL>N<RA-EN--G-LSR------------------34
CNGA4------------------------------>-<------------------------------
CNGB1SITE----------------DPAQILGHGS>T<GDTGCTDE-PNE------------------145
CNGB3------------------------------>-<------------------------------
HCN1------------------------------>-<------------------------------
HCN2------------------------------>-<------------------------------
HCN3------------------------------>-<------------------------------
HCN4--EDAEEEG-AGGRQDPSRRSIRLRPLPSP>S<PSAAAGGTESRSSALGAADSEGPARGAGKS87
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.R73Cc.217C>T Putative BenignSIFT:
Polyphen: