Paralogue Annotation for KCNH2 residue 754

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 754
Reference Amino Acid: L - Leucine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNH2 residue 754

No paralogue variants have been mapped to residue 754 for KCNH2.



KCNH2LQADICLHLNRSLLQHCKPFRGATKGCLRA>L<AMKFKTTHAPPGDTLVHAGDLLTALYFISR784
KCNH1MRADICVHLNRKVFKEHPAFRLASDGCLRA>L<AMEFQTVHCAPGDLIYHAGESVDSLCFVVS623
KCNH3LRADIAMHLHKEVL-QLPLFEAASRGCLRA>L<SLALRPAFCTPGEYLIHQGDALQALYFVCS624
KCNH4LRADIAMHLNREIL-QLPLFGAASRGCLRA>L<SLHIKTSFCAPGEYLLRRGDALQAHYYVCS598
KCNH5MRADICVHLNRKVFNEHPAFRLASDGCLRA>L<AVEFQTIHCAPGDLIYHAGESVDALCFVVS592
KCNH6LQADICLHLHRALLQHCPAFSGAGKGCLRA>L<AVKFKTTHAPPGDTLVHLGDVLSTLYFISR636
KCNH7LQADICLHLNQTLLQNCKAFRGASKGCLRA>L<AMKFKTTHAPPGDTLVHCGDVLTALYFLSR787
KCNH8LRSDITMHLNKEIL-QLSLFECASRGCLRS>L<SLHIKTSFCAPGEYLLRQGDALQAIYFVCS593
CNGA1LRAEIAINVHLDTLKKVRIFADCEAGLLVE>L<VLKLQPQVYSPGDYICKKGDIGREMYIIKE521
CNGA2LRAEIAINVHLSTLKKVRIFHDCEAGLLVE>L<VLKLRPQVFSPGDYICRKGDIGKEMYIIKE496
CNGA3LKAEIAINVHLDTLKKVRIFQDCEAGLLVE>L<VLKLRPTVFSPGDYICKKGDIGKEMYIINE524
CNGA4LRAEVAVSVHLSTLSRVQIFQNCEASLLEE>L<VLKLQPQTYSPGEYVCRKGDIGQEMYIIRE390
CNGB1MRLDLAIDVNYNIVSKVALFQGCDRQMIFD>M<LKRLRSVVYLPNDYVCKKGEIGREMYIIQA1004
CNGB3VQLALAIDVNFSIISKVDLFKGCDTQMIYD>M<LLRLKSVLYLPGDFVCKKGEIGKEMYIIKH566
HCN1LREEIVNFNCRKLVATMPLFANADPNFVTA>M<LSKLRFEVFQPGDYIIREGAVGKKMYFIQH517
HCN2LREEIVNFNCRKLVASMPLFANADPNFVTA>M<LTKLKFEVFQPGDYIIREGTIGKKMYFIQH586
HCN3LREEIINFTCRGLVAHMPLFAHADPSFVTA>V<LTKLRFEVFQPGDLVVREGSVGRKMYFIQH470
HCN4LREEIINFNCRKLVASMPLFANADPNFVTS>M<LTKLRFEVFQPGDYIIREGTIGKKMYFIQH637
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Leu754Argc.2261T>G UnknownSIFT:
Polyphen: