No paralogue variants have been mapped to residue 778 for KCNH2.
| KCNH2 | KGCLRALAMKFKTTHAPPGDTLVHAGDLLT>A<LYFISRGSIEILRG-D--V--VVAILGKND | 803 |
| KCNH1 | DGCLRALAMEFQTVHCAPGDLIYHAGESVD>S<LCFVVSGSLEVIQD-D--E--VVAILGKGD | 642 |
| KCNH3 | RGCLRALSLALRPAFCTPGEYLIHQGDALQ>A<LYFVCSGSMEVLKG-G--T--VLAILGKGD | 643 |
| KCNH4 | RGCLRALSLHIKTSFCAPGEYLLRRGDALQ>A<HYYVCSGSLEVLRD-N--M--VLAILGKGD | 617 |
| KCNH5 | DGCLRALAVEFQTIHCAPGDLIYHAGESVD>A<LCFVVSGSLEVIQD-D--E--VVAILGKGD | 611 |
| KCNH6 | KGCLRALAVKFKTTHAPPGDTLVHLGDVLS>T<LYFISRGSIEILRD-D--V--VVAILGKND | 655 |
| KCNH7 | KGCLRALAMKFKTTHAPPGDTLVHCGDVLT>A<LYFLSRGSIEILKD-D--I--VVAILGKND | 806 |
| KCNH8 | RGCLRSLSLHIKTSFCAPGEYLLRQGDALQ>A<IYFVCSGSMEVLKD-S--M--VLAILGKGD | 612 |
| CNGA1 | AGLLVELVLKLQPQVYSPGDYICKKGDIGR>E<MYIIKEGKLAVVAD-D--GVTQFVVLSDGS | 542 |
| CNGA2 | AGLLVELVLKLRPQVFSPGDYICRKGDIGK>E<MYIIKEGKLAVVAD-D--GVTQYALLSAGS | 517 |
| CNGA3 | AGLLVELVLKLRPTVFSPGDYICKKGDIGK>E<MYIINEGKLAVVAD-D--GVTQFVVLSDGS | 545 |
| CNGA4 | ASLLEELVLKLQPQTYSPGEYVCRKGDIGQ>E<MYIIREGQLAVVAD-D--GITQYAVLGAGL | 411 |
| CNGB1 | RQMIFDMLKRLRSVVYLPNDYVCKKGEIGR>E<MYIIQAGQVQVLGGPDGKS--VLVTLKAGS | 1026 |
| CNGB3 | TQMIYDMLLRLKSVLYLPGDFVCKKGEIGK>E<MYIIKHGEVQVLGGPDGTK--VLVTLKAGS | 588 |
| HCN1 | PNFVTAMLSKLRFEVFQPGDYIIREGAVGK>K<MYFIQHGVAGVITK-S--S--KEMKLTDGS | 536 |
| HCN2 | PNFVTAMLTKLKFEVFQPGDYIIREGTIGK>K<MYFIQHGVVSVLTK-G--N--KEMKLSDGS | 605 |
| HCN3 | PSFVTAVLTKLRFEVFQPGDLVVREGSVGR>K<MYFIQHGLLSVLAR-G--A--RDTRLTDGS | 489 |
| HCN4 | PNFVTSMLTKLRFEVFQPGDYIIREGTIGK>K<MYFIQHGVVSVLTK-G--N--KETKLADGS | 656 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.A778T | c.2332G>A | Putative Benign | SIFT: Polyphen: |