Paralogue Annotation for KCNH2 residue 923

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 923
Reference Amino Acid: P - Proline
Protein Domain: C-terminus


Paralogue Variants mapped to KCNH2 residue 923

No paralogue variants have been mapped to residue 923 for KCNH2.



KCNH2--EQ-----PGEVSALGPGRAGAGPSSRGR>P<GG---P--WGESPSSGPSS-------PESS941
KCNH1LFQRF-----RQQKEARL-AAERGGRDLDD>L<DV---E--KGNVLTEHASA-------NHSL782
KCNH3LEEKE-----TDGEQG---P-TVSPAPADE>P<SS---P--LLSPGCTSSSSAAKLLSPRRTA774
KCNH4ITEAE-----SGAEPGGGPRPR-RPLLLPN>L<SP---A--RPR--GSLVSLLGEELPPFSAL772
KCNH5LFQKF-----KQQKELRNQGSTQGDPERNQ>L<QV---E--SRSLQNGASIT-------GTSV752
KCNH6--ELGPQFPSKGYSLLGPGSQNSMG----->-<AG---P--CAPG-HPDAAP-------PLSI788
KCNH7------------NSTNDPEDSADTIRHYQS>S<KR---H--FEEKKSRSSSF-------ISSI941
KCNH8IVEDE-----EEEEEGEEEEAVSLSPICTR>G<SS---S--RNKKVGSNKAYLGLSLKQLASG759
CNGA1ARILA-----EYESMQQKLKQRLTKVEKFL>K<P-----LIDTEFSSIEGPG---------AE683
CNGA2GRLLA-----EYTGAQQKLKQRITVLETKM>K<Q-----NNEDDYLSDGMNS---------PE657
CNGA3ARLLA-----EYNATQMKMKQRLSQLESQV>K<G-----GG-DKPLADGEVPG-------DAT687
CNGA4ARLLA-----ELESSALKIAYRIERLEWQT>R<EW---PMPEDLAEADDEGE---------PE555
CNGB1AKGGK-----LAHLRARLKELAALEAAAKQ>Q<EL---V--EQAKSSQDVKGE-------EGS1167
CNGB3---------------ARLLKLKREQAAQKK>E<NSEGGE--EEGKENEDKQKE-------NED725
HCN1DREMV-----QAIAPINYPQMTTLNSTSST>T<TP---T--SRMRTQSPPVYT-------ATS672
HCN2DREMV-----QQAELGQRVGLFPPPPPPPQ>V<TS---A--IATLQQAAAMSF-------CPQ741
HCN3DRDMA-----RGVRGRAPSTGAQLSGKPVL>W<EP---L--VHAPLQAAAVTS-------NVA621
HCN4DREMA-----HCAHRVQAAASATPTPTPVI>W<TP---L--IQAPLQAAAATT-------SVA792
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.P923Lc.2768C>T Putative BenignSIFT:
Polyphen: