Paralogue Annotation for KCNH2 residue 989

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 989
Reference Amino Acid: G - Glycine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNH2 residue 989

No paralogue variants have been mapped to residue 989 for KCNH2.



KCNH2-------------------EKSSDTCNPLS>G<-AFSGVSNIFS-------------------999
KCNH1------------------ECLGPKGGGGDC>A<K----RKSWAR-------------------839
KCNH3------------------LRLPPMPWNVPP>D<LSPRVVDGIED-------------------830
KCNH4------------------LLIPPLGTFGPP>D<LSPRIVDGIED-------------------833
KCNH5------------------ADQKCLKVNSPI>R<MKNGNGKGWLR-------------------813
KCNH6------------------LEQLQAQMNRLE>S<RVSSDLSRILQ-------------------849
KCNH7------------------IDKRSHSCKDIT>D<MRSWERENAHP-------------------1002
KCNH8------------------LQLSTLNNAGPP>D<LSPRIVDGIED-------------------819
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<--E---------------------------563
CNGB1------------------------------>-<------A-----------------------1180
CNGB3------------------------------>-<------N-----------------------737
HCN1--SPCSYTTAVCSPPVQSPLAARTFHYASP>T<ASQLSLMQ----------------------731
HCN2-RPPPGPAPAAASPG------------PPP>P<ASP---------------------------780
HCN3-RSAWRSAGSPASPL------------VPV>R<AGPWASTS----------------------669
HCN4ARSPQAAQPSPAPPGARGGLGLPEHFLPPP>P<SSRSPSSSPGQLGQPPGELSLGLATGPLST993
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.G989Sc.2965G>A Putative BenignSIFT:
Polyphen: