Paralogue Annotation for KCNH2 residue 990

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 990
Reference Amino Acid: A - Alanine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNH2 residue 990

No paralogue variants have been mapped to residue 990 for KCNH2.



KCNH2-----------------EKSSDTCNPLSG->A<FSGVSNIFS---------------------999
KCNH1----------------ECLGPKGGGGDCAK>-<---RKSWAR---------------------839
KCNH3----------------LRLPPMPWNVPPDL>S<PRVVDGIED---------------------830
KCNH4----------------LLIPPLGTFGPPDL>S<PRIVDGIED---------------------833
KCNH5----------------ADQKCLKVNSPIRM>K<NGNGKGWLR---------------------813
KCNH6----------------LEQLQAQMNRLESR>V<SSDLSRILQ---------------------849
KCNH7----------------IDKRSHSCKDITDM>R<SWERENAHP---------------------1002
KCNH8----------------LQLSTLNNAGPPDL>S<PRIVDGIED---------------------819
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<E-----------------------------563
CNGB1------------------------------>-<----A-------------------------1180
CNGB3------------------------------>-<----N-------------------------737
HCN1SPCSYTTAVCSPPVQSPLAARTFHYASPTA>S<QLSLMQ------------------------731
HCN2PPPGPAPAAASPG------------PPPPA>S<P-----------------------------780
HCN3SAWRSAGSPASPL------------VPVRA>G<PWASTS------------------------669
HCN4SPQAAQPSPAPPGARGGLGLPEHFLPPPPS>S<RSPSSSPGQLGQPPGELSLGLATGPLSTPE995
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.A990Tc.2968G>A Putative BenignSIFT:
Polyphen: