No paralogue variants have been mapped to residue 210 for KCNQ1.
| KCNQ1 | CRSKYVGLWGRLRFARKPISIIDLIVVVAS>M<VVLCVG----------------SKGQVFAT | 224 |
| KCNQ2 | CCCRYRGWRGRLKFARKPFCVIDIMVLIAS>I<AVLAAG----------------SQGNVFAT | 194 |
| KCNQ3 | CCCRYKGWRGRLKFARKPLCMLDIFVLIAS>V<PVVAVG----------------NQGNVLA- | 223 |
| KCNQ4 | CCCRYRGWQGRFRFARKPFCVIDFIVFVAS>V<AVIAAG----------------TQGNIFAT | 200 |
| KCNQ5 | CCCRYRGWQGRLRFARKPFCVIDTIVLIAS>I<AVVSAK----------------TQGNIFAT | 228 |
| KCNA1 | ----FFACPSKTDFFKNIMNFIDIVAIIPY>F<ITLGTEIAEQEG-------N-QKGEQATSL | 288 |
| KCNA10 | ----FVVCPSKTDFFRNIMNIIDIISIIPY>F<ATLITELVQETEP---------SAQQNMSL | 337 |
| KCNA2 | ----FFACPSKAGFFTNIMNIIDIVAIIPY>F<ITLGTELAEKPE-------DAQQGQQAMSL | 290 |
| KCNA3 | ----FFACPSKATFSRNIMNLIDIVAIIPY>F<ITLGTELAERQ----------GNGQQAMSL | 360 |
| KCNA4 | ----CFACPSQALFFKNIMNIIDIVSILPY>F<ITLGTDLAQQQGG------GNGQQQQAMSF | 440 |
| KCNA5 | ----FFACPSKAGFSRNIMNIIDVVAIFPY>F<ITLGTELAEQQ---PGGGGGGQNGQQAMSL | 396 |
| KCNA6 | ----FSACPSKPAFFRNIMNIIDLVAIFPY>F<ITLGTELVQQQEQQPASGGGGQNGQQAMSL | 338 |
| KCNA7 | ----LLVCPSKAIFFKNVMNLIDFVAILPY>F<VALGTELARQR----------GVGQQAMSL | 274 |
| KCNB1 | ----FLSSPKKWKFFKGPLNAIDLLAILPY>Y<VTIFLTES---N--------KSVLQFQNVR | 293 |
| KCNB2 | ----FLSSPNKWKFFKGPLNVIDLLAILPY>Y<VTIFLTES---N--------KSVLQFQNVR | 297 |
| KCNC1 | ----VIFCPNKVEFIKNSLNIIDFVAILPF>Y<LEVGLSG-------------LSSKAAKDVL | 307 |
| KCNC2 | ----IVFSPNKLEFIKNLLNIIDFVAILPF>Y<LEVGLSG-------------LSSKAAKDVL | 344 |
| KCNC3 | ----ITFCPDKVEFLKSSLNIIDCVAILPF>Y<LEVGLSG-------------LSSKAAKDVL | 410 |
| KCNC4 | ----IVCCPDTLDFVKNLLNIIDFVAILPF>Y<LEVGLSG-------------LSSKAARDVL | 343 |
| KCND1 | ----LFAAPSRCRFLRSVMSLIDVVAILPY>Y<IGLLVP------------------KNDDVS | 288 |
| KCND2 | ----LAAAPSRYRFVRSVMSIIDVVAILPY>Y<IGLVMT------------------DNEDVS | 286 |
| KCND3 | ----LFAAPSRYRFIRSVMSIIDVVAIMPY>Y<IGLVMT------------------NNEDVS | 283 |
| KCNF1 | ----LFSSPNKLHFALSFMNIVDVLAILPF>Y<VSLTLTHL-----------GARMMELTNVQ | 286 |
| KCNG1 | ----LIQAPSKFAFLRSPLTLIDLVAILPY>Y<ITLLVDGAAAGRR----KPGAGNSYLDKVG | 339 |
| KCNG2 | ----SLQAESKCAFLRAPLNIIDILALLPF>Y<VSLLLGL-----A----AGPGGTKLLERAG | 284 |
| KCNG3 | ----FIVSKNKCEFVKRPLNIIDLLAITPY>Y<ISVLMTV-----------FTGENSQLQRAG | 285 |
| KCNG4 | ----FVQAQDKCQFFQGPLNIIDILAISPY>Y<VSLAVSEEPPEDG----ERPSGSSYLEKVG | 333 |
| KCNS1 | ----LLLAPSTRNFFCHPLNLIDIVSVLPF>Y<LTLLAGVALG-D--------QGGKEFGHLG | 338 |
| KCNS2 | ----FAVAPDFLKFFKNALNLIDLMSIVPF>Y<ITLVVNLV---V--------ESTPTLANLG | 291 |
| KCNS3 | ----LAAAPCQKKFWKNPLNIIDFVSIIPF>Y<ATLAVDTK---E--------EESEDIENMG | 286 |
| KCNV1 | ----FLCVRDRCRFLRKVPNIIDLLAILPF>Y<ITLLVESLSG-S--------QTTQELENVG | 308 |
| KCNV2 | ----LASTPDLRRFARSALNLVDLVAILPL>Y<LQLLLECFTGEGH----QRGQTVGSVGKVG | 373 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.M210I | c.630G>A | Putative Benign | SIFT: Polyphen: | ||
| p.Met210Thr | c.629T>C | Unknown | SIFT: Polyphen: |