Paralogue Annotation for KCNQ1 residue 468

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 468
Reference Amino Acid: S - Serine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 468

No paralogue variants have been mapped to residue 468 for KCNQ1.



KCNQ1DPPEERRL--------DHFSVDGYDSSVRK>S<PTLLEV---SM-------------------476
KCNQ2SPSADQSLED-SPSKVPKSW--SFGDRSRA>R<QAF------RIKG-----------------500
KCNQ3TPLNVDAIEE-SPSKEPKPV--GLNNKERF>R<TAF------RMKA-----------------480
KCNQ4SPSSEQVGEATSPTKVQKSW--SFNDRTRF>R<ASL------RLK------------------498
KCNQ5SPSTDITAEG-SPTKVQKSW--SFNDRTRF>R<PSL------RLKS------------S----482
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1----ARSSSSPQH-----L----------->-<---NVQQLEDMYNKMAKTQ--SQPILNTKE549
KCNB2EQLNNTSSSSPQH-----L----------->-<---SAQKLEMLYNEITKTQPHSHPNPDCQE562
KCNC1------------------------------>-<------------------------------
KCNC2------------------------------>-<------------------------------
KCNC3------------------------------>-<------------------------------
KCNC4------------------------------>-<------------------------------
KCND1-----F------------T----------->-<---DEL------------------------497
KCND2-----F------------V----------->-<---DEQ------------------------497
KCND3-----F------------I----------->-<---DEQ------------------------514
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.S468Gc.1402A>G Putative BenignSIFT:
Polyphen: