Paralogue Annotation for KCNQ1 residue 476

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 476
Reference Amino Acid: M - Methionine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 476

No paralogue variants have been mapped to residue 476 for KCNQ1.



KCNQ1-----DHFSVDGYDSSVRKSPTLLEV---S>M<------------------------------476
KCNQ2SPSKVPKSW--SFGDRSRARQAF------R>I<KG----------------------------500
KCNQ3SPSKEPKPV--GLNNKERFRTAF------R>M<KA----------------------------480
KCNQ4SPTKVQKSW--SFNDRTRFRASL------R>L<K-----------------------------498
KCNQ5SPTKVQKSW--SFNDRTRFRPSL------R>L<KS------------S---------------482
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1QH-----L---------------NVQQLED>M<YNKMAKTQ--SQPILNTKESAAQ-SKPKEE559
KCNB2QH-----L---------------SAQKLEM>L<YNEITKTQPHSHPNPDCQEKPERPSAYEEE573
KCNC1------------------------------>-<------------------------------
KCNC2------------------------------>-<------------------------------
KCNC3------------------------------>-<------------------------------
KCNC4------------------------------>-<------------------------------
KCND1-------T---------------DEL---->-<------------------------------497
KCND2-------V---------------DEQ---->-<------------------------------497
KCND3-------I---------------DEQ---->-<------------------------------514
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Met476Valc.1426A>G UnknownSIFT:
Polyphen: