Paralogue Annotation for KCNQ1 residue 488

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 488
Reference Amino Acid: D - Aspartate
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 488

No paralogue variants have been mapped to residue 488 for KCNQ1.



KCNQ1---PHFMRTN----------------SFAE>D<LDL---------------------------491
KCNQ2-AASRQNSEE----------------ASLP>G<EDI---------------------------517
KCNQ3--YAFWQSSE----------------DAGT>G<DPM---------------------------496
KCNQ4----PRTSAE----------------DA-P>S<EEV---------------------------511
KCNQ5-QPKPVIDAD----------------TALG>T<DDV---------------------------499
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1TEGVIDMRSMSSIDSFISCATDFPEATRFS>H<SP---LTSLP------------SKTGGSTA621
KCNB2TEVIVDMKSTSSIDSFTSCATDFTETERSP>L<PPPSASHLQMKFPTDLPGTEEHQRARGPPF651
KCNC1---------------------------CPH>I<DQA---------------------------525
KCNC2---------------------------STG>S<EPP---------------------------551
KCNC3---------------------------CPA>I<DQP---------------------------683
KCNC4---------------------------GAG>L<TQP---------------------------561
KCND1-TFSEALGAV----------------SPGG>R<T-S---------------------------513
KCND2-VFEESCMEV----------------ATVN>R<PSS---------------------------514
KCND3-MFEQNCMES----------------SMQN>Y<PST---------------------------531
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.D488Ec.1464C>A Putative BenignSIFT:
Polyphen: