Paralogue Annotation for KCNQ1 residue 550

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 550
Reference Amino Acid: L - Leucine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 550

No paralogue variants have been mapped to residue 550 for KCNQ1.



KCNQ1--YFVAKKKFQQARKPYDVRDVIEQYSQGH>L<NLMVRIKELQRRLDQSIGKPSLFIS-----575
KCNQ2--FLVSKRKFKESLRPYDVMDVIEQYSAGH>L<DMLSRIKSLQSRVDQIVGRGPAITD--KDR604
KCNQ3--FRLYKKKFKETLRPYDVKDVIEQYSAGH>L<DMLSRIKYLQTRIDMIFTPGPPSTP--KHK583
KCNQ4--FLVAKRKFKETLRPYDVKDVIEQYSAGH>L<DMLGRIKSLQTRVDQIVGRGPGDRKAREKG600
KCNQ5--FHVAKRKFKETLRPYDVKDVIEQYSAGH>L<DMLCRIKSLQTRVDQILGKGQITSD-KKSR587
KCNA1--TD-------------------------->-<------------------------------494
KCNA10--SR-------------------------->-<------------------------------510
KCNA2--TD-------------------------->-<------------------------------498
KCNA3--TD-------------------------->-<------------------------------574
KCNA4--TD-------------------------->-<------------------------------652
KCNA5RETD-------------------------->-<------------------------------612
KCNA6--TE-------------------------->-<------------------------------528
KCNA7--TE-------------------------->-<------------------------------455
KCNB1--EG-------DPSPLLPVLGMYHDPLRNR>G<SAAAAVAGLECA------------------711
KCNB2--ENRGSAPQTPPSTARPLPVTTADFSLTT>P<QHISTILLEETP------------------761
KCNC1--LSTGEYACPPGGGMRK----------DL>C<KESP---VIAKY------------------576
KCNC2--LTTGDYTCASDGGIRKG----YEKSRSL>N<NIAGLAGNALRL------------------614
KCNC3--LT--DYAPSPDGSIRKATGAPPLPPQDW>R<KPGPPS-FLPDL------------------747
KCNC4--LSTGDYACA-DGSVRKG----TFVLRDL>P<LQHSP---EAAC------------------624
KCND1--LDMLA--GLRRSHAPQSRSSLNAKPHDS>L<DLNCDSRDFVAA------------------597
KCND2--LSTIQIRCVERTPLSNSRSSLNAKMEEC>V<KLNCEQPYVTTA------------------596
KCND3--LSTIHIQGSEQPSLTTSRSSLNLKADDG>L<RPNCKTSQITTA------------------613
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.L550Ic.1648C>A Putative BenignSIFT:
Polyphen: