No paralogue variants have been mapped to residue 70 for KCNQ1.
| KCNQ1 | GALYAPIAPGAPGP--------APPASPAA>P<AAPPVASDL---GPRPPVSL------DPRV | 91 |
| KCNQ2 | --------A-PK---------------RGS>I<LS----------KPRAGG--AGAGK-PPKR | 70 |
| KCNQ3 | ------------DEG-----QR---R---->T<PQ----------GIGL-LAKTPLSRPVKRN | 100 |
| KCNQ4 | ------RRLGLLGSP-----L------PPG>A<PLP---------GPGSGSGSACGQR-SSAA | 76 |
| KCNQ5 | ------ATLGGGGGG-----LRESRRGKQG>A<RMS---------LLGKPL-SYTSSQ-SCRR | 104 |
| KCNA1 | NEYFFDRNRPSFDAILYYYQSGGRLRRPVN>V<PLDMFSEEIKFYELGEEAME----K--FRE | 132 |
| KCNA10 | NEYFFDRNRPSFDGILYYYQSGGKIRRPAN>V<PIDIFADEISFYELGSEAMD----Q--FRE | 181 |
| KCNA2 | NEYFFDRNRPSFDAILYYYQSGGRLRRPVN>V<PLDIFSEEIRFYELGEEAME----M--FRE | 128 |
| KCNA3 | NEYFFDRNRPSFDAILYYYQSGGRIRRPVN>V<PIDIFSEEIRFYQLGEEAME----K--FRE | 199 |
| KCNA4 | NEYFFDRNRPSFDAILYYYQSGGRLKRPVN>V<PFDIFTEEVKFYQLGEEALL----K--FRE | 271 |
| KCNA5 | NEYFFDRNRPSFDGILYYYQSGGRLRRPVN>V<SLDVFADEIRFYQLGDEAME----R--FRE | 215 |
| KCNA6 | NEYFFDRNRPSFDAILYYYQSGGRLRRPVN>V<PLDIFLEEIRFYQLGDEALA----A--FRE | 136 |
| KCNA7 | REYFFDRHRPSFDAVLYYYQSGGRLRRPAH>V<PLDVFLEEVAFYGLGAAALA----R--LRE | 108 |
| KCNB1 | NEYFFDRHPGAFTSILNFYRT-GRLHMMEE>M<CALSFSQELDYWGIDEIYLE----S--CCQ | 134 |
| KCNB2 | NEYFFDRHPGAFTSILNFYRT-GKLHMMEE>M<CALSFGQELDYWGIDEIYLE----S--CCQ | 138 |
| KCNC1 | DEFFFDRHPGVFAHILNYYRT-GKLHCPAD>V<CGPLYEEELAFWGIDETDVE----P--CCW | 106 |
| KCNC2 | REFFFDRHPGVFAYVLNYYRT-GKLHCPAD>V<CGPLFEEELAFWGIDETDVE----P--CCW | 153 |
| KCNC3 | DEFFFDRHPGVFAYVLNYYRT-GKLHCPAD>V<CGPLFEEELGFWGIDETDVE----A--CCW | 186 |
| KCNC4 | CEFFFDRHPGVFAYVLNYYRT-GKLHCPAD>V<CGPLFEEELTFWGIDETDVE----P--CCW | 145 |
| KCND1 | GEYFFDRDPDMFRHVLNFYRT-GRLHCPRQ>E<CIQAFDEELAFYGLVPELVG----D--CCL | 133 |
| KCND2 | QQYFFDRDPDIFRHILNFYRT-GKLHYPRH>E<CISAYDEELAFFGLIPEIIG----D--CCY | 134 |
| KCND3 | KEYFFDRDPEVFRCVLNFYRT-GKLHYPRY>E<CISAYDDELAFYGILPEIIG----D--CCY | 133 |
| KCNF1 | REFYFDRDPDAFKCVIEVYYF-GEVHMKKG>I<CPICFKNEMDFWKVDLKFLD----D--CCK | 128 |
| KCNG1 | NEFFFDRNPGAFGTILTFLRA-GKLRLLRE>M<CALSFQEELLYWGIAEDHLD----G--CCK | 166 |
| KCNG2 | DEFFFDRSPCAFRAIVALLRA-GKLRLLRG>P<CALAFRDELAYWGIDEARLE----R--CCL | 120 |
| KCNG3 | NEYFFDRHSEAFGFILLYVRGHGKLRFAPR>M<CELSFYNEMIYWGLEGAHLE----Y--CCQ | 113 |
| KCNG4 | QEFFFDRSPSAFGVIVSFLAA-GKLVLLQE>M<CALSFQEELAYWGIEEAHLE----R--CCL | 162 |
| KCNS1 | REFYFDRHPGFFLSLLHFYRT-GHLHVLDE>L<CVFAFGQEADYWGLGENALA----A--CCR | 153 |
| KCNS2 | REFYFDRNPELFPYVLHFYHT-GKLHVMAE>L<CVFSFSQEIEYWGINEFFID----S--CCS | 120 |
| KCNS3 | KEYYFDRNPSLFRYVLNFYYT-GKLHVMEE>L<CVFSFCQEIEYWGINELFID----S--CCS | 118 |
| KCNV1 | NEYFFDRSSQAFRYVLHYYRT-GRLHVMEQ>L<CALSFLQEIQYWGIDELSID----S--CCR | 152 |
| KCNV2 | DEYFFDRDPAVFQLVYNFYLS-GVLLVLDG>L<CPRRFLEELGYWGVRLKYTP----R--CCR | 200 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.Pro70Thr | c.208C>A | Unknown | SIFT: Polyphen: |