No paralogue variants have been mapped to residue 77 for KCNQ1.
| KCNQ1 | APGAPGP--------APPASPAAPAAPPVA>S<DL---GPRPPVSL------DPRVSIYSTRR | 98 |
| KCNQ2 | -A-PK---------------RGSILS---->-<-----KPRAGG--AGAGK-PPKRNAFYRK- | 76 |
| KCNQ3 | -----DEG-----QR---R----TPQ---->-<-----GIGL-LAKTPLSRPVKRNNAKYRR- | 106 |
| KCNQ4 | RLGLLGSP-----L------PPGAPLP--->-<-----GPGSGSGSACGQR-SSAAHKRYRR- | 82 |
| KCNQ5 | TLGGGGGG-----LRESRRGKQGARMS--->-<-----LLGKPL-SYTSSQ-SCRRNVKYRR- | 110 |
| KCNA1 | NRPSFDAILYYYQSGGRLRRPVNVPLDMFS>E<EIKFYELGEEAME----K--FREDEGF--- | 136 |
| KCNA10 | NRPSFDGILYYYQSGGKIRRPANVPIDIFA>D<EISFYELGSEAMD----Q--FREDEGF--- | 185 |
| KCNA2 | NRPSFDAILYYYQSGGRLRRPVNVPLDIFS>E<EIRFYELGEEAME----M--FREDEGY--- | 132 |
| KCNA3 | NRPSFDAILYYYQSGGRIRRPVNVPIDIFS>E<EIRFYQLGEEAME----K--FREDEGF--- | 203 |
| KCNA4 | NRPSFDAILYYYQSGGRLKRPVNVPFDIFT>E<EVKFYQLGEEALL----K--FREDEGF--- | 275 |
| KCNA5 | NRPSFDGILYYYQSGGRLRRPVNVSLDVFA>D<EIRFYQLGDEAME----R--FREDEGF--- | 219 |
| KCNA6 | NRPSFDAILYYYQSGGRLRRPVNVPLDIFL>E<EIRFYQLGDEALA----A--FREDEGC--- | 140 |
| KCNA7 | HRPSFDAVLYYYQSGGRLRRPAHVPLDVFL>E<EVAFYGLGAAALA----R--LREDEGC--- | 112 |
| KCNB1 | HPGAFTSILNFYRT-GRLHMMEEMCALSFS>Q<ELDYWGIDEIYLE----S--CCQARYHQKK | 141 |
| KCNB2 | HPGAFTSILNFYRT-GKLHMMEEMCALSFG>Q<ELDYWGIDEIYLE----S--CCQARYHQKK | 145 |
| KCNC1 | HPGVFAHILNYYRT-GKLHCPADVCGPLYE>E<ELAFWGIDETDVE----P--CCWMTYRQHR | 113 |
| KCNC2 | HPGVFAYVLNYYRT-GKLHCPADVCGPLFE>E<ELAFWGIDETDVE----P--CCWMTYRQHR | 160 |
| KCNC3 | HPGVFAYVLNYYRT-GKLHCPADVCGPLFE>E<ELGFWGIDETDVE----A--CCWMTYRQHR | 193 |
| KCNC4 | HPGVFAYVLNYYRT-GKLHCPADVCGPLFE>E<ELTFWGIDETDVE----P--CCWMTYRQHR | 152 |
| KCND1 | DPDMFRHVLNFYRT-GRLHCPRQECIQAFD>E<ELAFYGLVPELVG----D--CCLEEYRDRK | 140 |
| KCND2 | DPDIFRHILNFYRT-GKLHYPRHECISAYD>E<ELAFFGLIPEIIG----D--CCYEEYKDRR | 141 |
| KCND3 | DPEVFRCVLNFYRT-GKLHYPRYECISAYD>D<ELAFYGILPEIIG----D--CCYEEYKDRK | 140 |
| KCNF1 | DPDAFKCVIEVYYF-GEVHMKKGICPICFK>N<EMDFWKVDLKFLD----D--CCKSHLSEKR | 135 |
| KCNG1 | NPGAFGTILTFLRA-GKLRLLREMCALSFQ>E<ELLYWGIAEDHLD----G--CCKRRYLQKI | 173 |
| KCNG2 | SPCAFRAIVALLRA-GKLRLLRGPCALAFR>D<ELAYWGIDEARLE----R--CCLRRLRRRE | 127 |
| KCNG3 | HSEAFGFILLYVRGHGKLRFAPRMCELSFY>N<EMIYWGLEGAHLE----Y--CCQRRLDDRM | 120 |
| KCNG4 | SPSAFGVIVSFLAA-GKLVLLQEMCALSFQ>E<ELAYWGIEEAHLE----R--CCLRKLLRKL | 169 |
| KCNS1 | HPGFFLSLLHFYRT-GHLHVLDELCVFAFG>Q<EADYWGLGENALA----A--CCRARYLERR | 160 |
| KCNS2 | NPELFPYVLHFYHT-GKLHVMAELCVFSFS>Q<EIEYWGINEFFID----S--CCSYSYHGRK | 127 |
| KCNS3 | NPSLFRYVLNFYYT-GKLHVMEELCVFSFC>Q<EIEYWGINELFID----S--CCSNRYQERK | 125 |
| KCNV1 | SSQAFRYVLHYYRT-GRLHVMEQLCALSFL>Q<EIQYWGIDELSID----S--CCRDRYFRRK | 159 |
| KCNV2 | DPAVFQLVYNFYLS-GVLLVLDGLCPRRFL>E<ELGYWGVRLKYTP----R--CCRICFEERR | 207 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.S77F | c.230C>T | Putative Benign | SIFT: Polyphen: |