Paralogue Annotation for RYR1 residue 1231

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 1231
Reference Amino Acid: R - Arginine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 1231

No paralogue variants have been mapped to residue 1231 for RYR1.



RYR1LNLGQDVSSLRFFAICGLQEGFEPFAINMQ>R<PVTTWFSKGLPQFEPVPLEHPHYEVSRVDG1261
RYR2MNFGKDVSTLKYFTICGLQEGYEPFAVNTN>R<DITMWLSKRLPQFLQVPSNHEHIEVTRIDG1275
RYR3MNLGTDASTFKFYTMCGLQEGFEPFAVNMN>R<DVAMWFSKRLPTFVNVPKDHPHIEVMRIDG1261
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.R1231Hc.3692G>A Putative BenignSIFT: deleterious
Polyphen: probably damaging
p.R1231Cc.3691C>T Putative BenignSIFT:
Polyphen: