Paralogue Annotation for RYR1 residue 140

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 140
Reference Amino Acid: A - Alanine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 140

No paralogue variants have been mapped to residue 140 for RYR1.



RYR1HAHSRMYLSCLTTSRSMTDKLAFDVGLQED>A<TGEACWWTMHPASKQRSEGEKVRVGDDIIL170
RYR2HSYSGMYLCCLSTSRSSTDKLAFDVGLQED>T<TGEACWWTIHPASKQRSEGEKVRVGDDLIL183
RYR3HSFSGMYLTCLTTSRSQTDKLAFDVGLREH>A<TGEACWWTIHPASKQRSEGEKVRIGDDLIL173
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.A140Tc.418G>A Putative BenignSIFT:
Polyphen: possibly damaging
p.A140Sc.418G>T Putative BenignSIFT:
Polyphen: