Paralogue Annotation for RYR1 residue 1405

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 1405
Reference Amino Acid: P - Proline
Protein Domain:

Paralogue Variants mapped to RYR1 residue 1405

No paralogue variants have been mapped to residue 1405 for RYR1.

RYR1	EKDATTEKNKKRGFLFKAKKVAMMTQPPAT>P<TLPRLPHDVVPADNRDDPEIILNTTTYYYS	1435
RYR2	--DYAQEKP-SR--LKQRFLLRRTKPDYST>S<HSARLTEDVLADDRDDYDFLMQT-STYYYS	1429
RYR3	------------------------------>-<-SPCLDSEAFQKRKQMQEILSHTTTQCYYA	1331
cons	> <

See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.P1405T	c.4213C>A	Putative Benign		rs376567445	SIFT: tolerated Polyphen: possibly damaging