Paralogue Annotation for RYR1 residue 1425

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 1425
Reference Amino Acid: I - Isoleucine
Protein Domain:

Paralogue Variants mapped to RYR1 residue 1425

No paralogue variants have been mapped to residue 1425 for RYR1.

RYR1	VAMMTQPPATPTLPRLPHDVVPADNRDDPE>I<ILNTTTYYYSVRVFAGQEPSCVWAGWVTPD	1455
RYR2	LRRTKPDYSTSHSARLTEDVLADDRDDYDF>L<MQT-STYYYSVRIFPGQEPANVWVGWITSD	1449
RYR3	------------SPCLDSEAFQKRKQMQEI>L<SHTTTQCYYAIRIFAGQDPSCVWVGWVTPD	1351
cons	> <

See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.I1425V	c.4273A>G	Putative Benign			SIFT: Polyphen: