Paralogue Annotation for RYR1 residue 1685

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 1685
Reference Amino Acid: C - Cysteine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 1685

No paralogue variants have been mapped to residue 1685 for RYR1.



RYR1RLDLQRFHSHTLRLYRAVCALGNNRVAHAL>C<SHVDQAQLLHALEDAHLPGPLRAGYYDLLI1715
RYR2QEELLKFHYHTLRLYSAVCALGNHRVAHAL>C<SHVDEPQLLYAIENKYMPGLLRAGYYDLLI1707
RYR3QEDLMRFHYHTLRLYSAVCALGNSRVAYAL>C<SHVDLSQLFYAIDNKYLPGLLRSGFYDLLI1611
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.C1685Yc.5054G>A Putative BenignSIFT: deleterious
Polyphen: probably damaging
p.C1685Gc.5053T>G Putative BenignSIFT:
Polyphen: