Paralogue Annotation for RYR1 residue 1781

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 1781
Reference Amino Acid: C - Cysteine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 1781

No paralogue variants have been mapped to residue 1781 for RYR1.



RYR1RSTENGHPRHGLPGVGVTTSLRPPHHFSPP>C<FVAALPAAGAAEAPARLSPAIPLEALRDKA1811
RYR2-----ENKKHGLPGIGLSTSLRPRMQFSSP>S<FVSI------SNECYQYSPEFPLDILKSKT1791
RYR3-----ESKRHGLPGVGLRTCLKPGFRFSTP>C<FVVT------GEDHQKQSPEIPLESLRTKA1695
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.C1781Rc.5341T>C Putative BenignSIFT: tolerated
Polyphen: possibly damaging