Paralogue Annotation for RYR1 residue 1887

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 1887
Reference Amino Acid: E - Glutamate
Protein Domain:


Paralogue Variants mapped to RYR1 residue 1887

No paralogue variants have been mapped to residue 1887 for RYR1.



RYR1EDVKQILKMIEPEVFTEEEEEEDEEEEGEE>E<DEEEKEEDEEETAQEKEDEEKEEEEAAEGE1917
RYR2EDLKHILQLIEPSVFKEAATPEEESDTL-->E<-K---ELS----VDDAK-LQGAGEE--EAK1884
RYR3DDVRQILLLIDPSVFGEHSAGTEEGAEK-->E<-E---VTQ----VEEKA-VEAG-----EKA1785
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.E1887Qc.5659G>C Putative BenignSIFT: tolerated
Polyphen: benign
p.E1887Kc.5659G>A Putative BenignSIFT:
Polyphen: