Paralogue Annotation for RYR1 residue 2186

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 2186
Reference Amino Acid: M - Methionine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 2186

No paralogue variants have been mapped to residue 2186 for RYR1.



RYR1LECLGQIRSLLIVQMGPQEENLMIQSIGNI>M<NNKVFYQHPNLMRALGMHETVMEVMVNVLG2216
RYR2LASLGQIRSLLSVRMGKEEEKLMIRGLGDI>M<NNKVFYQHPNLMRALGMHETVMEVMVNVLG2180
RYR3LAALGQIRSLLSVRMGKEEELLMINGLGDI>M<NNKVFYQHPNLMRVLGMHETVMEVMVNVLG2078
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.M2186Vc.6556A>G Putative BenignSIFT:
Polyphen: benign