Paralogue Annotation for RYR1 residue 2385

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 2385
Reference Amino Acid: R - Arginine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 2385

No paralogue variants have been mapped to residue 2385 for RYR1.



RYR1RLLIRKPECFGPALRGEGGSGLLAAIEEAI>R<ISEDPARDGPGIRRDRRREHFGEEPPEENR2415
RYR2RLLIRRPECFGPALRGEGGNGLLAAMEEAI>K<IAEDPSRDGPSPNS-GSSKTLDTEEEEDDT2381
RYR3KLLIRRPECFGPALRGEGGNGLLAAMQGAI>K<ISENPALDLPSQGY-KREVSTGDDEEEEEI2278
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.R2385Cc.7153C>T Putative BenignSIFT:
Polyphen: possibly damaging
p.R2385Hc.7154G>A Putative BenignSIFT:
Polyphen: