Paralogue Annotation for RYR1 residue 2386

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 2386
Reference Amino Acid: I - Isoleucine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 2386

No paralogue variants have been mapped to residue 2386 for RYR1.



RYR1LLIRKPECFGPALRGEGGSGLLAAIEEAIR>I<SEDPARDGPGIRRDRRREHFGEEPPEENRV2416
RYR2LLIRRPECFGPALRGEGGNGLLAAMEEAIK>I<AEDPSRDGPSPNS-GSSKTLDTEEEEDDTI2382
RYR3LLIRRPECFGPALRGEGGNGLLAAMQGAIK>I<SENPALDLPSQGY-KREVSTGDDEEEEEIV2279
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.I2386Nc.7157T>A Putative BenignSIFT:
Polyphen: