Paralogue Annotation for RYR1 residue 2422

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 2422
Reference Amino Acid: I - Isoleucine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 2422

No paralogue variants have been mapped to residue 2422 for RYR1.



RYR1RDGPGIRRDRRREHFGEEPPEENRVHLGHA>I<MSFYAALIDLLGRCAPEMHLIQAGKGEALR2452
RYR2RDGPSPNS-GSSKTLDTEEEEDDTIHMGNA>I<MTFYSALIDLLGRCAPEMHLIHAGKGEAIR2418
RYR3LDLPSQGY-KREVSTGDDEEEEEIVHMGNA>I<MSFYSALIDLLGRCAPEMHLIQTGKGEAIR2315
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.I2422Vc.7264A>G Putative BenignSIFT:
Polyphen: