Paralogue Annotation for RYR1 residue 3425

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 3425
Reference Amino Acid: T - Threonine
Protein Domain:

Paralogue Variants mapped to RYR1 residue 3425

No paralogue variants have been mapped to residue 3425 for RYR1.

RYR1	RDEFSVLCRDLYALYPLLIRYVDNNRAQWL>T<EPNPSAEELFRMVGEIFIYWSKSHNFKREE	3455
RYR2	LDEFTTLARDLYAFYPLLIRFVDYNRAKWL>K<EPNPEAEELFRMVAEVFIYWSKSHNFKREE	3416
RYR3	LDEFAVLCRDLYAFYPMLIRYVDNNRSNWL>K<SPDADSDQLFRMVAEVFILWCKSHNFKREE	3312
cons	> <

See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.T3425M	c.10274C>T	Putative Benign		rs150977342	SIFT: Polyphen: benign
p.T3425R	c.10274C>G	Putative Benign			SIFT: Polyphen: