Paralogue Annotation for RYR1 residue 3580

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 3580
Reference Amino Acid: P - Proline
Protein Domain:


Paralogue Variants mapped to RYR1 residue 3580

No paralogue variants have been mapped to residue 3580 for RYR1.



RYR1REFLHNNLHLQGKVEGSPSLRWQMALYRGV>P<GREEDADDPEKIVRRV-------------Q3597
RYR2RDIIRSNIHLQGKLE-DPAIRWQMALYKDL>P<NRTDDTSDPEKTVERVLDIANVLFHLEQKS3565
RYR3REHLRNNLHLQEKSD-DPAVKWQLNLYKDV>L<K-SEEPFNPEKTVERV-------------Q3452
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.P3580Lc.10739C>T Putative BenignSIFT:
Polyphen: