Paralogue Annotation for RYR1 residue 4189

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 4189
Reference Amino Acid: I - Isoleucine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 4189

No paralogue variants have been mapped to residue 4189 for RYR1.



RYR1LHNFLELAESILEYFRPYLGRIEIMGASRR>I<ERIYFEISETNRAQWEMPQVKESKRQFIFD4219
RYR2LQTFLELAESVLNYFQPFLGRIEIMGSAKR>I<ERVYFEISESSRTQWEKPQVKESKRQFIFD4175
RYR3LKCLLDPAESVLNYFEPYLGRIEIMGGAKK>I<ERVYFEISESSRTQWEKPQVKESKRQFIFD4071
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.I4189Vc.12565A>G Putative BenignSIFT:
Polyphen: