Paralogue Annotation for RYR1 residue 437

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 437
Reference Amino Acid: I - Isoleucine
Protein Domain:

Paralogue Variants mapped to RYR1 residue 437

No paralogue variants have been mapped to residue 437 for RYR1.

RYR1	NGLYNQFIKSLDSFSGKPRGSGPPAGTALP>I<EGVILSLQDLIIYFEPPSEDLQHEEKQSKL	467
RYR2	VFLFNRFIRGLDALSKKAKA----STVDLP>I<ESVSLSLQDLIGYFHPPDEHLEHEDKQNRL	479
RYR3	TALFSQFVSGN-----NRTA----APITLP>I<EEVLQTLQDLIAYFQPPEEEMRHEDKQNKL	466
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See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.I437M	c.1311C>G	Putative Benign			SIFT: Polyphen: